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Senior Director, Global Medicinal Chemistry

Japan, Fujisawa · Job Posted July 03, 2026
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Job Description

We are seeking a seasoned and visionary Senior Director of Medicinal Chemistry to join our leadership team. This individual will play a pivotal role in shaping the future direction of our company by providing strategic guidance and oversight to our medicinal chemistry efforts. The ideal candidate will be instrumental in driving our drug discovery initiatives forward, ensuring their successful progression and alignment with our company's overall goals and objectives. By leveraging their expertise, they will significantly influence our strategic decisions and contribute to the advancement of our scientific and commercial endeavors. Additionally, this person will oversee external programs at CROs, managing the design, execution, and progression of medicinal chemistry projects conducted exclusively at these organizations

Job Responsibility

  • Create business development opportunities that meet the strategic scientific, therapeutic, and commercial needs of the organization or specific Therapeutic Area (TA)
  • Provide strategic leadership and oversight to the medicinal chemistry department, aligning with the company's overall goals and objectives
  • Oversee the design, execution, and management of medicinal chemistry projects conducted exclusively at CROs, ensuring timely progress and high-quality outcomes
  • Mentor and develop a team of internal chemists, fostering a collaborative and innovative work environment
  • Work closely with cross-functional teams, including biology, pharmacology, and clinical development, to advance drug candidates from discovery through development
  • Drive innovation in medicinal chemistry through the integration of new technologies, methodologies, and best practices
  • Ensure all activities comply with relevant regulatory requirements and industry standards
  • Build and maintain relationships with external partners, including academic institutions, industry collaborators, and contract research organizations

Requirements

  • PhD degree in Chemistry, Medicinal Chemistry or related discipline with 15+ years experience in small molecule projects
  • Proven track record of leading successful drug discovery programs, preferably in large pharma
  • Strong leadership and managerial skills with experience leading and developing high-performing teams
  • Deep understanding of medicinal chemistry principles, drug design, and optimization processes
  • Excellent verbal and written communication skills, with the ability to effectively communicate complex scientific concepts to a broad audience
  • Strong analytical and problem-solving skills, with a proactive and innovative approach to challenges
  • Proven ability to work collaboratively in a cross-functional team environment
  • Ability to adapt to changing priorities and work effectively in a fast-paced and dynamic environment

Nice to have

  • Experience in a leadership role within a large pharmaceutical or biotechnology company is highly desirable
  • A proven track record of leading projects that are completely outsourced
  • A strong publication record in medicinal chemistry or related fields
  • Experience with patent filings and intellectual property management
  • Established network within the scientific and pharmaceutical community

What we offer

  • Commutation
  • Housing
  • Overtime Work
  • Salary Increase Annually
  • Bonus Payment Twice a year
  • Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)
  • Paid Leaves: Annual Paid Leave, Special Paid Leave, Sick Leave, Family Support Leave, Maternity Leave, Childcare Leave, Family Nursing Leave
  • Flexible Work Styles: Flextime, Telework
  • Social Insurance
  • Retirement and Corporate Pension
  • Employee Stock Ownership Program

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