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Moderna Logo Moderna · IT - Administration

Senior Director, Global Medical Affairs, Oncology

United States, Cambridge 210900.00 - 379200.00 USD / Year · Job Posted May 03, 2026
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Job Description

Moderna is seeking a Global Medical Director to lead medical affairs strategy across our Oncology portfolio, spanning early development through commercialization. This role offers a unique opportunity to influence the direction of mRNA oncology programs from a scientific and strategic perspective, with a strong emphasis on external engagement, data generation, and cross-functional alignment. As a key member of the global Medical Affairs team, you will be responsible for integrated evidence planning, medical governance leadership, and driving scientific thought leadership worldwide. The role will interface extensively with regulatory, clinical, commercial, and external stakeholders to ensure the success of Moderna’s oncology assets. This is a high-impact position suited for a strategic thinker, scientific storyteller, and matrix leader with a passion for innovation in oncology. The successful candidate will report to the VP, Head of Medical Affairs Oncology.

Job Responsibility

  • Owning and leading the global medical strategy across Moderna’s oncology portfolio, ensuring seamless integration from early development to lifecycle management
  • Serving as final medical accountability for assigned oncology programs, including delivery of the integrated medical plan
  • Driving medical leadership in governance bodies and cross-functional decision-making forums, ensuring alignment between development, regulatory, and commercial functions
  • Leading the Development Integrated Evidence Team to build comprehensive data packages for regulators, payers, and other stakeholders
  • Acting as global medical lead in interactions with health authorities and payers, providing strategic input and medical representation
  • Directing a cross-functional global medical matrix team (Scientific Communications, Field Medical, Patient Advocacy), ensuring timely execution of deliverables
  • Leading global launch readiness for oncology assets, including medical training, evidence generation, scientific engagement, and narrative development
  • Building partnerships with global, regional, and national thought leaders to shape best practices and influence health policy
  • Developing and executing publication strategies, medical education initiatives, and real-world evidence programs to strengthen knowledge exchange
  • Managing medical affairs budget and resource planning for assigned programs, aligning with broader franchise objectives
  • Partnering with the VP, Oncology and cross-functional stakeholders to shape the long-term medical direction and investment strategy for the franchise

Requirements

  • MD or non-US equivalent, PharmD, or PhD with extensive oncology medical affairs leadership experience
  • Minimum of 15 years of experience in Medical Affairs, with a strong track record in global roles
  • Demonstrated leadership of global launch planning and execution in oncology or immuno-oncology settings
  • Deep expertise in oncology therapeutic area required
  • Strong strategic thinking and leadership skills in a global medical affairs role
  • Experience in regulatory, scientific communication, and external stakeholder engagement
  • Launch experience global and/or locally

Nice to have

  • melanoma and immunotherapy experience preferred
  • Strong track record of KOL engagement, scientific communication, and external representation
  • Experience navigating strategic external collaborations and cross-company governance
  • Expertise in cross-functional team leadership, including pharmacovigilance, biostatistics, clinical operations, and regulatory affairs
  • Strategic and operational mindset with excellent project leadership capabilities
  • Comfort managing cross-functional deliverables and owning timelines and outputs at a program level
  • Exceptional communication skills with the ability to translate complex science into clear, impactful messaging
  • Ability to thrive in a fast-paced environment, balancing strategic leadership with hands-on execution
  • A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative

What we offer

  • Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
  • Family planning benefits, including fertility, adoption, and surrogacy support
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
  • Savings and investment opportunities to help you plan for the future
  • Location-specific perks and extras
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