Senior Director, Global Forecasting, Obesity Job at Amgen (Thousand Oaks)

Job Description

Let’s do this. Let’s change the world. Amgen is committed to transforming the lives of patients by advancing science, delivering innovative medicines, and creating sustainable value for healthcare systems worldwide. Obesity represents one of the most pressing global health challenges of our time, with rapidly evolving science, treatment paradigms, competitive dynamics, access considerations, and patient needs shaping the future of care. To support this important therapeutic area, we are seeking a Senior Director, Global Forecasting, Obesity to lead forecasting strategy and execution for Amgen’s global obesity portfolio. This leader will be responsible for developing robust, evidence-based forecasts that inform portfolio strategy, investment decisions, launch planning, lifecycle management, resource allocation, and long-range business planning. The Senior Director will partner closely with Global Commercial, U.S. Commercial, Regional Commercial, Finance, Medical, Market Access, R&D, Business Development, Market Research, Analytics, and Competitive Intelligence teams to ensure forecasts reflect aligned assumptions, rigorous methodology, and a forward-looking view of market evolution. The role requires a strategic forecasting leader who can operate in ambiguity, influence senior stakeholders, build organizational confidence in forecast outputs, and translate complex market dynamics into clear business implications.

Job Responsibility

Lead global forecasting for Amgen’s obesity portfolio, including pipeline assets, launch brands, lifecycle opportunities, and long-range therapeutic area planning
Develop and maintain short-term, mid-term, and long-range forecasts that support strategic planning, investment decisions, portfolio prioritization, and performance expectations
Establish clear forecasting frameworks, methodologies, governance, and assumptions across global, regional, and U.S. stakeholders
Translate forecast outputs into actionable strategic recommendations for senior leadership
Serve as a trusted forecasting advisor to Global Commercial, Finance, R&D, Medical, Market Access, and regional leadership teams
Ensure forecasts are credible, transparent, and grounded in robust data, business logic, and cross-functional alignment
Build forecasts that reflect the complexity of the global obesity market, including treatment adoption, patient flow, diagnosis and treatment rates, payer dynamics, adherence, persistence, capacity constraints, competitor entry, and evolving standards of care
Incorporate global and local market dynamics, including epidemiology, pricing and reimbursement, access restrictions, regional launch sequencing, promotional investment, and healthcare system differences
Evaluate key forecast drivers such as patient segmentation, demand generation, product profile, differentiation, market expansion, switching, discontinuation, and competitive response
Develop scenarios to assess upside and downside risks across major markets and regions
Partner with cross-functional teams to assess commercial implications of clinical data, label scenarios, indication expansion, device or formulation changes, and lifecycle opportunities
Support business development, licensing, and external innovation assessments as needed through objective commercial forecasting
Ensure forecasts directly inform global brand strategy, launch planning, annual operating plans, long-range planning, portfolio reviews, and investment trade-off decisions
Partner with Finance to align forecast outputs with financial planning cycles, revenue expectations, and business performance management
Collaborate with Market Access and Pricing teams to reflect reimbursement scenarios, access timing, net price assumptions, payer restrictions, and affordability considerations
Partner with Market Research, Analytics, and Competitive Intelligence to ensure forecasts are informed by the best available evidence and updated as new insights emerge
Develop clear narratives that explain forecast movement, key assumptions, risks, sensitivities, and strategic implications
Prepare executive-ready materials for senior leadership discussions, governance forums, portfolio reviews, and business planning meetings
Lead cross-functional forecast alignment processes across global, regional, and U.S. teams
Ensure seamless forecast transitions from global strategy to regional and U.S. execution, with consistent assumptions, transparent methodology, and clear ownership
Drive forecast quality through disciplined model design, assumption documentation, sensitivity analysis, version control, and governance
Establish best practices for obesity forecasting, including launch curve development, analog selection, patient-based modeling, scenario planning, and competitive event modeling
Identify opportunities to enhance forecasting capabilities through advanced analytics, automation, real-world evidence, and improved data integration
Maintain a clear view of forecast risks and opportunities, proactively advising leadership on changes in market outlook
Partner with Global General Managers, regional commercial leaders, U.S. leadership, Finance, R&D, Medical, Market Access, Supply, Manufacturing, and Strategy teams to align around forecast assumptions and business implications
Influence senior stakeholders in a highly matrixed global organization
Facilitate productive debate around key assumptions while driving alignment and decision-making
Ensure global forecasts reflect local market realities while maintaining enterprise-level consistency
Build strong relationships across functions to ensure forecasting is embedded into strategic decision-making, not treated as a standalone exercise
Lead, develop, and mentor forecasting talent supporting the obesity portfolio
Foster a culture of analytical rigor, transparency, accountability, curiosity, and business partnership
Champion diversity, equity, and inclusion within the team and across forecasting processes
Build forecasting capability across the organization by coaching teams on methodology, assumptions, scenario planning, and interpretation of forecast outputs
Encourage innovation while maintaining disciplined forecasting standards

Requirements

Doctorate degree and 5 years of experience in forecasting, analytics, market insights, finance, strategy, or commercial planning
Master’s degree and 9 years of experience in forecasting, analytics, market insights, finance, strategy, or commercial planning
Bachelor’s degree and 11 years of experience in forecasting, analytics, market insights, finance, strategy, or commercial planning
at least 5 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources
Deep biopharmaceutical forecasting expertise, ideally with experience in obesity, metabolic disease, diabetes, cardiovascular disease, or other large primary care or specialty markets
Strong understanding of global pharmaceutical markets, including launch dynamics, pricing and reimbursement, market access, regional variation, and competitive strategy
Experience developing patient-based forecasts, epidemiology-driven models, analog-based launch forecasts, scenario analyses, and long-range portfolio forecasts
Ability to integrate inputs from market research, secondary analytics, competitive intelligence, clinical development, medical, access, and finance into cohesive forecast recommendations
Strong executive communication skills, with the ability to distill complex models and assumptions into clear strategic narratives
Proven ability to challenge assumptions constructively, manage ambiguity, and make sound recommendations with incomplete information
Experience supporting major investment decisions, launch planning, lifecycle planning, business development assessments, or portfolio prioritization
Strong business acumen and ability to connect forecast implications to strategy, resource allocation, and enterprise value
High adaptability and comfort operating in a fast-moving therapeutic area with rapidly evolving competitive dynamics

Nice to have

Deep biopharmaceutical forecasting expertise, ideally with experience in obesity, metabolic disease, diabetes, cardiovascular disease, or other large primary care or specialty markets
Strong understanding of global pharmaceutical markets, including launch dynamics, pricing and reimbursement, market access, regional variation, and competitive strategy
Experience developing patient-based forecasts, epidemiology-driven models, analog-based launch forecasts, scenario analyses, and long-range portfolio forecasts
Ability to integrate inputs from market research, secondary analytics, competitive intelligence, clinical development, medical, access, and finance into cohesive forecast recommendations
Strong executive communication skills, with the ability to distill complex models and assumptions into clear strategic narratives
Proven ability to challenge assumptions constructively, manage ambiguity, and make sound recommendations with incomplete information
Experience supporting major investment decisions, launch planning, lifecycle planning, business development assessments, or portfolio prioritization
Strong business acumen and ability to connect forecast implications to strategy, resource allocation, and enterprise value
High adaptability and comfort operating in a fast-moving therapeutic area with rapidly evolving competitive dynamics

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible

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