CrawlJobs Logo

Senior Director, Gene Therapy Operations (Apheresis)

260000.00 - 320000.00 USD / Year · Job Posted January 21, 2026
Apply Position
Job Link Share

Job Description

Beam is seeking a highly talented and motivated Senior Directory, Gene Therapy Operations (Apheresis) leader to join our growing Commercial Patient Operations team. The Senior Director, Gene Therapy Operations will be responsible for leading Gene Therapy Operations, Apheresis team- the team responsible for 1) treatment center onboarding, training and qualification. 2) Patient Scheduling and Coordination for Apheresis and Drug Product Delivery. 3) Cell collection optimization support. 4) Drug Product storage, thawing, and administration support. The leader will be responsible for defining the strategy and scope and building their team, leading treatment center activation and patient coordination. This leader and their team must have a patient-centric and customer-focused approach to drive commercial launch readiness and execution for Beam’s lead asset, ristocel, an ex vivo autologous hematopoietic stem cell-based gene therapy for the treatment of severe sickle cell disease (SCD). This is a high impact role for Beam’s potential first product commercialization. The successful candidate plays a critical role in building and establishing commercial operations readiness for the company.

Job Responsibility

  • Develop and mentor a high performing Gene Therapy Operations, Apheresis team that is focused on delivering an excellent patient and stakeholder experience for commercial gene therapy from scheduling through infusion process
  • Develop and execute the strategic initiative and process for Treatment Center Qualification, training and ongoing support for patient coordination, scheduling, communication, cell collection support, and drug product infusion support
  • Drive Workflow & Training development: Design training to qualify apheresis and treatment centers, leading treatment center activation and certification processes and providing ongoing operational oversight post-activation
  • Quality & Compliance oversight: Ensuring compliance with regulatory standards (FACT, AABB), managing quality records (deviations, CAPAs, change controls) and overseeing the end-to-end process for patient apheresis and product delivery. Ensure COC/COI and assist in the implementation of ISBT-128 ST-018, as needed
  • Partner with Quality and Patient Operations team to build a robust treatment center network including center selection, qualification, training and ongoing support. Lead field team providing onsite support
  • Provide Apheresis expertise to support various internal activities and external facing training development
  • Create and conduct Apheresis and Cell therapy lab on-boarding, assessments, training, and collection support and other areas as needed
  • Build metrics program that will drive data collection and analysis in support of optimizing collection procedures, efficiency, and quality
  • Actively engage in the identification, sharing, and adaptation of best practices cross-functionally and between centers and identify and champion industry working group initiatives that will improve overall cell and gene therapy industry and treatment experience of our patients
  • Work closely across functions to ensure Chain of Identify and Chain of Custody are maintained throughout the patient journey

Requirements

  • Bachelor's degree or the combination of education and business experience required
  • Advanced degree preferred (e.g., MBA, RN, MPH, etc.)
  • Minimum 10+ years (18+ years) of healthcare or related experience, including significant experience within the biotech industry (especially with cell and gene therapy products)
  • Strong direct apheresis experience within the last 5 years
  • Strong preference for experience within Sickle Cell Disease and autologous cell & gene therapy
  • Qualification in Apheresis (QIA) certification preferred
  • Ability to work independently with very limited supervision
  • Ability to navigate and be successful in a fast-paced, highly matrixed work environment
  • Detail-oriented, able to assess and assimilate data and communicate objectively
  • Experience in commercial gene or cell therapy is greatly preferred
  • Good knowledge of GCPs, GMPs, AABB, FACT/JACIE, FDA, EMEA, MHRA, regulations
  • Effective teaching, training, planning, and problem-solving abilities
  • Willingness to travel domestically (30-50% of time)
  • Strong team player that has patient focused approach and is solution oriented
  • Excellent listening, communication and interpersonal skills foster team spirit
  • Excellent people management skills and a strong track record of developing people/talent and organizational capability
  • A passion for addressing the critical unmet medical needs of patients

Nice to have

  • Advanced degree preferred (e.g., MBA, RN, MPH, etc.)
  • Strong preference for experience within Sickle Cell Disease and autologous cell & gene therapy
  • Qualification in Apheresis (QIA) certification preferred
  • Experience in commercial gene or cell therapy is greatly preferred

Looking for more opportunities?

Search for other job offers that match your skills and interests.

Similar Jobs for

Senior Director, Gene Therapy Operations (Apheresis)

8 matching positions

Senior Director, Commercial Product and Vein-to-Vein Systems Operations

Beam is seeking a highly talented and motivated Senior Directory, Commercial Pro...
Location
Location
Salary
Salary:
260000.00 - 320000.00 USD / Year
beamtx.com Logo
Beam Therapeutics
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor's degree or the combination of education and business experience required
  • Minimum 10+ years of Quality Management, System Management or Commercial Product Operations in Cell and Gene Therapy
  • Experience supporting FDA BLA submission, inspection and commercial launch required
  • Experience building or maintaining traceability portal for cell or gene therapy required
  • Experience with Treatment Center Qualification and Activation for cell and gene therapy required
  • Strong direct cell or gene therapy commercial experience within the last 5 years
  • Ability to work independently with very limited supervision
  • Ability to navigate and be successful in a fast-paced, highly matrixed work environment
  • Detail-oriented, able to assess and assimilate data and communicate objectively
  • Good knowledge of GCPs, GMPs, AABB, FACT/JACIE, FDA, EMEA, MHRA, regulations
Job Responsibility
Job Responsibility
  • Establish and lead cross‑functional governance for commercial product execution, including clear ownership, escalation pathways, and decision rights
  • Drive readiness for regulatory inspections and audits related to commercial product operations and patient‑specific execution
  • Partner with Commercial, Patient Operations, Gene Therapy Operations, Quality, Supply Chain, and IT to ensure aligned and disciplined execution from order to infusion
  • Define and execute the COI/COC validation strategy, including SOPs, workflows, risk assessments, and control points across the full patient journey
  • Translate FDA, FACT, AABB, and other regulatory requirements into practical, auditable, end‑to‑end workflows
  • Own COI‑related deviation investigations with commercial impact, partnering with Quality and Operations to resolve issues and prevent recurrence
  • Design and lead a commercial exceptions management framework covering incoming apheresis material, manufactured drug product, logistics, scheduling, and site readiness issues
  • Lead investigations, root‑cause analyses, escalation management, and CAPA development across Commercial Product Operations in partnership with Manufacturing, Supply Chain, Quality, and Patient Operations
  • Provide clear, timely communication of execution risks, trends, and mitigation plans to senior leadership
  • Serve as the business and product owner for Beam’s workflow and traceability portal, partnering with IT on design, build, validation, and ongoing enhancements
  • Fulltime
Read More
Arrow Right

Business Development Manager

We are seeking a Business Development Manager to identify and secure new organic...
Location
Location
Australia , North Laverton
Salary
Salary:
125000.00 - 135000.00 AUD / Year
graincorp.com.au Logo
GrainCorp
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Skilled in engaging prospects through cold outreach
  • Experienced in overcoming objections and building rapport quickly
  • Sound communication and negotiation skills (written and oral)
  • Ability to deliver engaging proposals and presentations
  • Ability to build rapport at all levels (both internally and externally)
  • Time management and planning skills
  • Proficiency in MS Office and CRM software (e.g. Salesforce)
  • Determined, resilient and results focused
  • Ability to work well under pressure, identify opportunities and secure new business
Job Responsibility
Job Responsibility
  • Developing growth strategies and plans
  • Maintain a sound knowledge of the business equipment, service and value proposition
  • Increasing the customer base
  • Build long-term trusting relationships with customers and retention through service agreements
  • Drafting and reviewing contracts for new and existing business
  • Writing business proposals
  • Negotiating with stakeholders
  • Researching business opportunities and tailoring sales activities to convert
  • Reporting on successes and areas for improvement
  • Following industry trends in Australia and overseas
What we offer
What we offer
  • Professional development & leadership programs
  • Hybrid work and flexible leave options including birthday leave
  • Health & wellbeing support
  • Inclusive, values-driven culture
  • Fulltime
Read More
Arrow Right

Site Manager

As the Site Manager of our Caragabal site (travel to other sites is also a requi...
Location
Location
Australia , Caragabal
Salary
Salary:
Not provided
graincorp.com.au Logo
GrainCorp
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Experience supervising, supporting and developing workgroups / individuals
  • Ability and willingness to work flexible hours to meet operational demands
  • Capacity to work at heights and in confined spaces
  • Current unrestricted driver licence and basic IT literacy
  • Experience in plant operations (ideally the Grain industry)
Job Responsibility
Job Responsibility
  • Coordinate day-to-day activities of the team
  • coach and support development of team members
  • Get to know, understand and apply our enterprise agreement and people processes
  • Develop and maintain close relationships with local growers, customers, and the local community
  • Coordinate and prepare for area maintenance and pest control teams to deliver required services
  • Identify and report on maintenance requirements and maintain site presentation and standards
  • Manage programmes and initiatives related to safety ('zero harm' culture) and risk management
  • Fulltime
Read More
Arrow Right

Accounts Payable Clerk

We are looking for an experienced Accounts Payable Clerk to join a finance team ...
Location
Location
United States , Baltimore
Salary
Salary:
Not provided
https://www.roberthalf.com Logo
Robert Half
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s degree in Accounting, Finance, Business Administration, or a related discipline
  • At least 5 years of hands-on experience in accounts payable or broader accounting operations
  • Demonstrated understanding of invoice review, matching procedures, account coding, and journal entry preparation
  • Experience using enterprise accounting or ERP platforms
  • Strong Microsoft Excel skills
  • High level of accuracy, organization, and attention to detail in a deadline-driven environment
  • Effective written and verbal communication skills with the ability to resolve issues professionally
Job Responsibility
Job Responsibility
  • Process supplier invoices accurately and ensure all payment requests are reviewed before entry into the system
  • Compare purchase orders, receiving records, and invoices to confirm billing details and resolve mismatches promptly
  • Assign correct general ledger accounts and cost centers to payable transactions to support accurate financial reporting
  • Prepare accounts payable-related journal entries and record transactions in alignment with established accounting practices
  • Reconcile vendor statements, investigate outstanding items, and work with internal teams or suppliers to clear discrepancies
  • Maintain organized accounts payable files and supporting documentation for reference, compliance, and audit readiness
  • Execute recurring payment runs on a weekly and monthly basis while verifying timing and accuracy of disbursements
  • Contribute to month-end and year-end close activities by providing reconciliations, reports, and transaction support
  • Respond to vendor inquiries and coordinate with cross-functional departments to address billing or payment concerns
What we offer
What we offer
  • Medical, Vision, Dental, and Life and Disability insurance
  • 401(k) plan
  • Free online training
  • Access to top jobs
  • Competitive compensation and benefits
  • Fulltime
Read More
Arrow Right

Grain Handler

We are looking for 2 Grain Handlers to join our Mt McLaren QLD site (with occasi...
Location
Location
Australia , Kilcummin
Salary
Salary:
Not provided
graincorp.com.au Logo
GrainCorp
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • General labouring experience
  • Ability to work in confined spaces
  • Good work ethic
  • Valid drivers licence
  • Good communication skills
  • Safety-conscious behaviour
  • Reliability
  • Computer literacy
Job Responsibility
Job Responsibility
  • Receiving and handling grain
  • Cleaning and hygiene on site
  • Weighbridge operation
  • Loader Operator experience
What we offer
What we offer
  • ME! (birthday) leave
  • Tools and training
  • Genuine opportunities to take on more responsibility
  • Inclusive and supportive working culture
  • Fulltime
Read More
Arrow Right

Accounts Payable Specialist

A growing organization in Reston, VA is seeking an Accounts Payable Specialist t...
Location
Location
United States , Herndon
Salary
Salary:
Not provided
https://www.roberthalf.com Logo
Robert Half
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • 2+ years of accounts payable experience
  • Prior government contracting experience
  • Experience with Deltek Costpoint is a strong plus
  • Strong attention to detail and organizational skills
  • Ability to manage high-volume workloads and meet deadlines
  • Excellent communication skills
Job Responsibility
Job Responsibility
  • Process high-volume, full-cycle accounts payable, including invoice entry, coding, and approvals
  • Review and verify invoices for accuracy and proper documentation
  • Manage vendor relationships and handle inquiries in a timely manner
  • Perform account reconciliations and resolve discrepancies
  • Ensure compliance with company policies and government contracting requirements
  • Assist with month-end close and reporting related to AP
  • Support process improvements to increase efficiency and accuracy
What we offer
What we offer
  • medical
  • vision
  • dental
  • life and disability insurance
  • company 401(k) plan
  • Fulltime
Read More
Arrow Right

Assistant Site Manager

Location
Location
Australia , Burren Junction
Salary
Salary:
Not provided
graincorp.com.au Logo
GrainCorp
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Some experience in supervising teams (or the potential to)
  • Previous grain handling experience
  • Good communication skills, time management and IT literacy
  • Capability to work at heights and in confined spaces.
Job Responsibility
Job Responsibility
  • Coordinate day-to-day workflow of the team and support to attract, select, train, and develop permanent and casual team members
  • Develop and maintain relationships with growers, customers, local community groups and internal stakeholders
  • Assist the Site Manager to implement and review site budget, participate in site financial planning, and to achieve site targets
  • Support the resource planning for grain receival / outload activity during peak and off-peak periods
  • Support the planning and execution of scheduled and ad-hoc maintenance, grain protection, safety and quality activities and related reporting
  • Supervise a large seasonal workforce during our busy harvest intake periods, including at multiple sites.
  • Fulltime
Read More
Arrow Right

Grain Handler

We are seeking a Grain Handler for a permanent position to join our team based i...
Location
Location
Australia , Yamala
Salary
Salary:
Not provided
graincorp.com.au Logo
GrainCorp
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Proof of working rights
  • Driver's license
Job Responsibility
Job Responsibility
  • Receiving and handling grain
  • Cleaning and hygiene on site
  • Weighbridge operation
What we offer
What we offer
  • Ongoing training and safety programs
  • Paid Parental leave and birthday leave
  • Employee referral bonus scheme
  • Fulltime
Read More
Arrow Right