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10X Genomics is a life science technology company building tools that enable scientists to understand biology at single-cell resolution. We invest more than $250 million annually in R & D and operate at the intersection of hardware, software, and genomics — requiring a finance organization that is rigorous, collaborative, and capable of supporting rapid growth and technical complexity. The Senior Director, Accounting Operations serves as the Controller’s operational deputy, driving operational accounting excellence and process efficiencies that elevate the finance organization’s impact and better achieve strategic company goals across the entire accounting spectrum. This role is accountable for the accuracy, efficiency, and internal control environment across Cost Accounting, Corporate Accounting & GL, Accounts Payable, and Payroll. This is a high-trust leadership role for someone who combines deep technical accounting knowledge with strong operational instincts and the ability to develop talent. This role requires someone who leads with data - using financial and operational metrics to drive decisions and communicate clearly with senior leadership, and who builds trust through collaboration rather than control. The successful candidate will be a proven builder who can drive process improvement, partner cross-functionally, and serve as a stabilizing force during a period of organizational evolution.
Job Responsibility
Own end-to-end accounting operations including month-end and quarter-end close, ensuring accuracy, timeliness, and auditability across all sub-functions
Serve as day-to-day escalation point for accounting operations issues, proactively surfacing risks and driving resolution
Partner with the Internal Control team to build and maintain a strong internal control environment, and lead the remediation of any identified control deficiencies
Leverage financial data and metrics to identify trends, risks, and improvement opportunities, translating complex accounting information into clear, actionable insights for executive leadership
Partner with FP&A and business partners to ensure financial data integrity and support forecast and budget cycles
Oversee standard costing, manufacturing variance analysis, inventory valuation, and cost of goods sold reporting
Drive process mapping and documentation of cost accounting procedures to support operational continuity
Partner with operations and supply chain to ensure cost data accurately reflects manufacturing and production activity
Lead integration of cost accounting insights into management reporting and business reviews
Oversee GL integrity, chart of accounts governance, and intercompany accounting
Ensure month-end close activities are completed on schedule with appropriate review and reconciliation sign-off
Apply strong analytical judgement to complex accounting transactions, ensuring not just correct treatment but clear explanation of financial impact to non-accounting stakeholders
Manage AP functions with a focus on automation, vendor relationships, and working capital efficiency
Identify and implement systems-driven improvements to reduce manual effort and error rates
Ensure compliance with payment terms, procurement policy, and cash management practices
Oversee payroll operations for a multi-state workforce, ensuring accuracy, compliance, and timely processing
Evaluate ongoing payroll delivery model (in-house vs. PEO/outsourced) and recommend cost-effective solutions
Partner with HR and Legal on compensation changes, equity events, and regulatory compliance
Lead with collaborative, “we over me” mindset, modeling cross-functional partnership and holding the team accountable to the same standard
Mentor, develop, and retain a team of accounting professionals across Cost Accounting, Corporate Accounting, AP, and Payroll
Set clear performance expectations aligned with 10X Genomics’ values and build accountability structures that enable team members to grow
Drive adoption of AI-enabled tools and workflow automation to increase team capacity and quality
Partner with the Controller on headcount planning, role design, and succession planning
Represent the accounting function credibly in cross-functional leadership and partnership settings, communicating complex financial matters in a way that builds confidence and trust with leaders within the finance organization as well as outside the finance organization
Requirements
12+ years of progressive accounting experience, including direct responsibility for cost accounting in a manufacturing or life science environment
5+ years managing multi-functional accounting teams
Deep knowledge of US GAAP across cost accounting, GL, and payroll disciplines
Demonstrated experience driving close process improvements and building scalable accounting operations
Strong communication skills with the ability to translate accounting concepts for non-finance stakeholders
Proven track record of developing accounting talent and building team accountability
Nice to have
CPA license
Experience in a public company environment with a Big 4 or large regional firm background
Familiarity with Oracle, or equivalent ERP in a manufacturing context
Exposure to AI-enabled finance tools and process automation
What we offer
Equity grants
Comprehensive health and retirement benefit programs
Annual bonus program or sales incentive program
Competitive and comprehensive health benefits package
Competitive easy-to-use benefits that promote wellbeing and make your life easier
Family friendly policies like parental leave, and other benefits