CrawlJobs Logo

Senior Clinical Research Manager - Network Operations

dana-farber.org Logo

Dana-Farber Cancer Institute

Location Icon

Location:
United States , Brookline

Category Icon

Job Type Icon

Contract Type:
Not provided

Salary Icon

Salary:

105400.00 - 130500.00 USD / Year

Job Description:

The Senior Clinical Research Manager (CRM) provides strategic and operational oversight of the adult medical oncology clinical trial portfolio across six regional satellite locations within the Greater Boston and Southern New Hampshire areas, including Brighton, Milford, Weymouth, Methuen, Foxborough, MA & Londonderry, NH and any future satellite regional campus. The role is responsible for leading and managing the clinical research programs at these sites and for supervising the research staff engaged in the conduct of clinical trials in accordance with Good Clinical Practice, under the direction of the Principal Investigators and the Regional Campus Leadership Team. In close collaboration with the regional campus medical director, the research physician leads at each campus, and research nursing staff, the Senior CRM is responsible for the implementation and evaluation of both therapeutic and non-therapeutic clinical research activities, ensuring robust regulatory and compliance oversight. The Senior CRM provides direct supervision and professional development for the program’s clinical research staff and is responsible for monitoring and achieving clinical trial performance benchmarks, including protocol and regulatory compliance, patient safety, staff training and development, and financial targets, as defined by Senior Research Leadership and the Regional Campus Leadership Team.

Job Responsibility:

  • CLINICAL TRIAL OPERATIONS: Responsible for the oversight of their disease group's clinical trial portfolio and all related regulatory, compliance and performance metrics requirements.
  • Oversee the processing of protocols through DFCI Institutional Review Board (and other institutions' IRBs) when appropriate.
  • Collaborate with the DFCI Clinical Trials Office (CTO), the Office for Human Research Studies (OHRS) and the Quality Assurance for Clinical Trials (QACT) to fulfill local and federal requirements governing human clinical trials.
  • Identify and manage operational, logistical, and regulatory challenges related to the conduct of clinical trials and acts as a leader in overseeing their resolution.
  • Assist the principal investigator in developing the protocol budget, in collaboration with Research Administration and the Grants and Contracts offices. Work with grant managers and other financial managers in the reporting and accounting of these funds.
  • Oversees and coordinates the purchase, receipt, inventory and distribution of equipment utilized in the conduct of clinical trials.
  • Work collaboratively with clinical research administration and grant managers to help monitor and reconcile all study and related grant finances as needed.
  • Assists the principal investigator in preparing manuscripts for publication.
  • Collaborate with the DFCI CTO and DF/HCC QACT to develop study forms, database information, and to establish guidelines for monitoring data quality control for PI Initiated studies / Multi-Center Trials
  • Oversee the subject enrollment, protocol treatment and follow-up care processes for protocol patients.
  • Oversees registration of protocol patients with QACT, study group registrar and pharmaceutical company as outlined in protocol.
  • REGULATORY & COMPLIANCE: Assumes responsibility for essential document compliance for entire portfolio.
  • Implements systems to monitor and ensure regulatory document collection and maintenance compliance.
  • Assumes responsibilities for all clinical trial reporting requirements
  • safety event, annual approval, deviations etc.
  • Implements systems to monitor portfolio compliance.
  • Responsible for the disease group's transition from paper to electronic regulatory binders.
  • Will maintain per DFCI CTO standards.
  • DATA MANAGEMENT & CLINICAL TRIAL MONITORING: Assumes responsibilities for data management and compliance for entire portfolio.
  • Maintains schedules and procedures necessary for timely and complete data collection.
  • Regularly reports data compliance status to key stakeholders
  • i.e. DFCI PI, study Sponsor, DFCI CTO.
  • Implements corrective action to maintain data compliance when necessary.
  • Submits required "progress/tracking" reports to key stakeholders, when applicable.
  • STAFF HIRING, SUPERVISION, TRAINING & DEVELOPMENT: Responsible for the recruitment and oversight of all of the research staff.
  • Ensure that all staff complete required mandatory and ongoing training in a timely manner. Develops and oversees a program specific on-boarding and orientation process and conducts annual performance evaluations and competency assessments of research staff.
  • Develops a standard supervision schedule with research staff including periodic individual and group supervision meeting.
  • Will develop and agenda, take attendance and document all applicable meetings.
  • Will communicate all personnel concerns to their immediate supervisor and to DFCI HR partner for the appropriate response and follow up.

Requirements:

  • Bachelor’s Degree required, with a minimum of 7+ years of related experience or Master Degree with 5+ years experience.
  • Knowledge of cancer as a disease process, cancer treatment modalities, and the clinical trial process.
  • Experience in protocol development, data compilation and analysis.
  • Skilled at developing tracking systems to ensure timely data management by the clinical research staff.
  • Expert knowledge of Federal and State regulations as they relate to research.
  • Strong interpersonal, organizational and communication skills are required.
  • Must have computer skills including the use of Microsoft Office and working knowledge of Livelink
  • EPIC and OnCore applications.
  • Has expert knowledge of and is fully proficient in ability to execute clinical trials start-up, active and close out phases.
  • Is fully proficient in their knowledge of clinical research local policy and federal regulation.
  • Strong ability to independently navigate complex personnel issues in collaboration with key stakeholders.
  • Can navigate and or interpret complex regulatory strategy and can operationalize when applicable with little or no supervision.
  • Operates proactively to maintain compliance and best practice.
  • Able to problem solve and work collaboratively with key stakeholders.
  • May be asked to provide in-service training and can to serve as a resource to other clinical personnel including physicians, nurses, pharmacists and other allied health professionals regarding clinical trials, protocols, GCP guidelines, federal regulations and site SOPs.
  • Supervises study management staff, including clinical research coordinators, students, volunteers, and other research assistants.

Additional Information:

Job Posted:
December 26, 2025

Employment Type:
Fulltime
Work Type:
Hybrid work
Job Link Share:

Looking for more opportunities? Search for other job offers that match your skills and interests.

Briefcase Icon

Similar Jobs for Senior Clinical Research Manager - Network Operations

New

Clinical Operations Senior Project Manager

The Clinical Operations Project Manager ensures the oversight of the activities ...
Location
Location
United States , San Mateo
Salary
Salary:
147817.00 - 175014.00 USD / Year
dompe.com Logo
Dompé
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s/Master’s Degree in Pharmacology, Biotechnology or related scientific discipline
  • 7-12 years of experience in similar roles, preferably in the Pharmaceutical/Life-science sector
  • Project Management Certification is preferred
  • Languages: Italian English (fluent)
  • Knowledge of the main productivity and collaboration tools (Google Workspace, MS Office)
  • Knowledge of GCP/ICH phase I-IV clinical trials and observational studies
  • Knowledge of research and clinical trial methodologies
  • Knowledge of CRO industry
  • Knowledge of Project Management
  • Knowledge of Pharmaceutical sector
Job Responsibility
Job Responsibility
  • Supervises the CRO activities in all the study conduct phases (start-up, maintenance, study closure)
  • Is responsible to coordinate and drive in a functional matrix model the multidisciplinary team assigned to each of the company clinical trials
  • Is involved in the CRO process selection in compliance with current company SOPs
  • Is responsible for set-up and progress of the study according to the company current standards/regulation and ensures that committed targets are met until study completion
  • Collaborates with the local Medical Department and Site Engagement Manager to identify potential investigators to be included in the clinical network of Dompé
  • Collects and manages input to the study protocol and operational aspects of the study, participates in the planning of Investigator Meetings
  • Works with Local Drug Supply Management and ensures IMP is available to commence and complete assigned trial/assigned trial sites
  • Maintains knowledge of the study protocol to answer standard operational questions from CRAs of the CROs, sites, and internal Country/Cluster personnel
  • Ensures the performance of the CRO assigned to the study in order to be on time, budget and quality by collecting, analyzing and reporting detailed performance KPI dashboards
  • Closely collaborates in autonomy with the CRO project management team in order to ensure that anticipated study milestones and target are met and in order to put in place corrective or mitigation plans to address risks that may impact missing study objectives
What we offer
What we offer
  • Comprehensive medical benefits
  • Generous vacation / holiday time off
  • Competitive 401(K) matching
  • Fulltime
Read More
Arrow Right
New

Chief Medical Officer

The Chief Medical Officer, Canada, will be primarily responsible for ensuring Te...
Location
Location
Canada , Toronto
Salary
Salary:
Not provided
miramsbecker.com Logo
Mirams Becker
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • MD or equivalent medical degree from an accredited institution
  • Licensed (or eligible for licensure) with the College of Physicians and Surgeons of Ontario (CPSO) or equivalent
  • Minimum of 10 years of clinical experience, including 5 years in a leadership or administrative role
  • Demonstrated success in medical governance, quality improvement, and physician engagement
  • Strong understanding of Canada’s healthcare system, hospital operations, and regulatory requirements
  • Experience with accreditation processes and performance metrics
  • Excellent communication, negotiation, and team-building skills
Job Responsibility
Job Responsibility
  • Develop and lead the enterprise-wide clinical strategy, ensuring alignment with organizational goals and innovation in care delivery
  • Oversee the clinical delivery of medical services, ensuring effective coordination with operational, and quality teams
  • Provide medical leadership for clinical governance by interpreting quality, safety, and compliance insights and ensuring appropriate clinical response
  • Set and maintain clinical policies, standards, and protocols that define appropriate medical practice and support consistent, high quality care across virtual platforms, in collaboration with quality and operational partners
  • Be accountable for the clinical quality and safety of care delivered by the provider network, in alignment with established clinical best practices, regulatory standards, and accreditation requirements
  • Review and act on quality, safety, and experience insights generated through organizational quality measurement and reporting processes, including addressing identified risks or performance issues
  • Ensure appropriate clinical response to quality findings, including provider feedback, coaching, remediation, and training through the clinical education function, and escalation or offboarding where required
  • Lead associate medical directors, clinical education, and provider network management teams to ensure effective delivery of clinical services
  • Recruit, credential, and manage a multidisciplinary provider network, including physicians, nurse practitioners, and allied health professionals
  • Provide clinical leadership and mentorship, fostering a culture of continuous learning and improvement
What we offer
What we offer
  • Impactful, Connected Healthcare: Support millions of Canadians across the country with accessible care within rural regions & provincial health systems, at no cost to patients
  • Focus on Quality & Safety: Upholding the highest excellence of clinical quality standards is paramount to Teladoc Health
  • Collaborative, Supportive Network: Our diverse community is dedicated to transforming healthcare in Canada. Be a part of a growing team across Canada, that thrives on engagement, learning and growth
  • Our Work Truly Matters: Recognized as the world leader in whole-person virtual care, Teladoc Health uses innovative platforms to provide accessible care across the full continuum of care, at every stage in a person’s health journey
  • Growth and Innovation: We are growing rapidly - Come grow with us and support our expanding mission to make healthcare more accessible
  • Diversity and Inclusion: At Teladoc Health we believe that personal and professional diversity is the key to innovation. We hire based solely on your strengths and qualifications, and the way in which those strengths can directly contribute to your success in your new position
Read More
Arrow Right

Executive Director, Study Start-Up

In this vital role as Executive Director, Study Start-Up (SSU), you will lead SS...
Location
Location
United States , Thousand Oaks
Salary
Salary:
281634.00 - 336501.00 USD / Year
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Doctorate degree and 6 years of clinical execution experience
  • Master’s degree and 10 years of clinical execution experience
  • Bachelor’s degree and 12 years of clinical execution experience
  • 6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources
  • 12+ years’ work experience in life sciences industry, particularly focusing on clinical trial work, including 10+ years of biopharmaceutical clinical research experience obtained at a biotech or pharmaceutical company
  • Experience engaging and working across clinical trial teams in multiple geographies to deliver global clinical trials
  • Experience driving and leading organizations through cross-functional change initiatives such as identifying solutions to problems and innovating and change strategies and structure to meet future needs
  • Experience leading cross-functional / cross-geography / cross-trial teams, ensuring operational excellence and smooth decision-making
  • ability to escalate and resolve challenges in alignment with global study strategy priorities
  • Extensive knowledge of the clinical and pharmaceutical drug development process, from early to late-stage development with a deep understanding of relevant therapeutic areas to meet the highest scientific and regulatory standards
Job Responsibility
Job Responsibility
  • Shape the long-term vision and strategy of the SSU Hub, ensuring alignment with CPSO, GDO, and enterprise priorities
  • Integrate and harmonize strategies from the six sub-functions into a single global capability strategy, balancing standardization with local/regional adaptability
  • Act as the global escalation point for study start-up risks and issues, ensuring timely resolution and portfolio-level visibility
  • Embed within the industry - bringing outside ways of working and representing Amgen back into the industry
  • Build and develop a high-performing global SSU leadership team (Directors, Sr Managers) creating a culture of accountability, innovation and operational excellence
  • Lead, and mentor the global SSU Hub leadership team, ensuring robust succession planning, talent development, and organizational effectiveness
  • Drive consistent performance management, alignment, and calibration across sub-functions to ensure equitable resourcing and delivery
  • Embed a center of excellence mindset, encouraging knowledge-sharing and best practice adoption globally
  • Oversee start-up planning and execution across all new studies globally, ensuring timelines and quality standards are consistently achieved
  • Partner with Clinical Program Strategy and Operations TA Heads to ensure seamless integration of start-up into program execution
What we offer
What we offer
  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible
  • Fulltime
Read More
Arrow Right
New

Senior Clinical Research Associate

As a Clinical Research Associate (CRA) at Parexel, you act as an integral part t...
Location
Location
France , Paris Region
Salary
Salary:
Not provided
parexel.com Logo
Parexel
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Networking and relationship building skills
  • Ability to communicate effectively and appropriately with internal and external stakeholders
  • Ability to adapt to changing technologies and processes
  • Effectively overcoming barriers encountered during the implementation of new processes and systems
  • Excellent communication (verbal and written), presentation, and interpersonal skills relating to colleagues and associates, both inside and outside of the organization
  • Identifies and builds effective relationships with investigator site staff and other stakeholders
  • Proficiency in local language is required
  • Advanced level or fluency in English is required
  • Bachelor’s degree or Registered Nurse (RN) in a related field or equivalent combination of education, training, and experience
Job Responsibility
Job Responsibility
  • Ensuring regulatory, ICH-GCP and protocol compliance
  • Uses judgment and experience to evaluate overall performance of site and site staff and to provide recommendations regarding site-specific actions
  • immediately communicates/escalates significant issues to the project team and develops action plans
  • Maintains a working knowledge of ICH/GCP Guidelines or other applicable guidance, relevant regulations, and company Standard Operating Procedures (SOPs)/processes
  • Verifies the process of obtaining informed consent has been adequately performed and documented for each subject as required
  • Demonstrates diligence in protecting the confidentiality of each subject and assesses factors that might affect subject safety and clinical data integrity at an investigator site such as protocol deviation and violations and pharmacovigilance issues
  • Per the Clinical Monitoring Plan (CMP) or SMP: Ability to conduct monitoring activities using different methods, (e.g., both on site and remote) where allowed by country regulations
  • Conducts source document review and verification of appropriate site source documents and medical records
  • Verifies required clinical data entered in the Case Report Form (CRF) is accurate and complete
  • Manages reporting of protocol deviations and appropriate follow up
What we offer
What we offer
  • Flexible work arrangements
  • Career growth and development
  • Supportive and inclusive environment
  • Diverse therapeutic areas and project exposure
  • Advanced Technology
Read More
Arrow Right

Senior Clinical Research Associate

As a Clinical Research Associate (CRA) at Parexel, you act as an integral part t...
Location
Location
France , Paris Region
Salary
Salary:
Not provided
parexel.com Logo
Parexel
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s degree or Registered Nurse (RN) in a related field or equivalent combination of education, training, and experience
  • Networking and relationship building skills
  • Ability to communicate effectively and appropriately with internal and external stakeholders
  • Ability to adapt to changing technologies and processes
  • Excellent communication (verbal and written), presentation, and interpersonal skills
  • Identifies and builds effective relationships with investigator site staff and other stakeholders
  • Proficiency in local language is required
  • Advanced level or fluency in English is required
Job Responsibility
Job Responsibility
  • Responsible for data integrity, data quality and ensuring compliance with ICH GCP and local requirements at the site level
  • Monitoring will be conducted in line with the Study Monitoring Plan (SMP)
  • Collaborate with the Site Manager to assure that the site complies with the protocol and is inspection ready
  • Coordinate with institutions and investigators at the local level
  • Oversight of Monitoring Responsibilities and Study Conduct
  • Ensuring regulatory, ICH-GCP and protocol compliance
  • Uses judgment and experience to evaluate overall performance of site and site staff
  • Maintains a working knowledge of ICH/GCP Guidelines or other applicable guidance, relevant regulations, and company Standard Operating Procedures (SOPs)/processes
  • Verifies the process of obtaining informed consent has been adequately performed and documented for each subject
  • Demonstrates diligence in protecting the confidentiality of each subject and assesses factors that might affect subject safety and clinical data integrity
What we offer
What we offer
  • Patient-focused in everything we do
  • Supportive and inclusive environment
  • Career growth and development
  • Flexible work arrangements
  • Diverse therapeutic areas and project exposure
  • Advanced Technology
Read More
Arrow Right
New

Senior Key Account Manager Screening Solutions

The Sr Key Account Manager Screening Solutions will drive product growth and mar...
Location
Location
Canada , Calgary
Salary
Salary:
Not provided
exactsciences.com Logo
Exact Sciences
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s Degree in Life Sciences, Business, or related field
  • advanced degree preferred
  • 5+ years of experience in pharmaceutical or diagnostics sales, preferably in oncology or screening
  • Demonstrated ability to perform the essential duties of the position with or without accommodation
  • Deep understanding of Canadian healthcare system, reimbursement pathways, and screening protocols
  • Strong communication, negotiation, and stakeholder engagement skills
  • Experience with CRM tools and data-driven account planning
  • Possession of a valid driver’s license
  • no suspended, revoked, surrendered, invalid, etc. allowed
  • Applicants must be currently authorized to work in country where work will be performed on a full or part-time basis. We are unable to sponsor or take over sponsorship of employment visas at this time
Job Responsibility
Job Responsibility
  • Generate deep insight into Canadian healthcare ecosystems and market landscape to identify opportunities for improved patient outcomes through integration of screening solutions
  • Analyze the treatment journey across the local system of care to identify account opportunities and work with HCPs to improve clinical decision making and population health outcomes
  • Build a network of relationships within accounts to gain insight into system, customer, and patient unmet needs, including clinical stakeholders and administrators
  • Capture information on customer interactions using CRM tools, including point of contact information, sales call activities, market intelligence, funnel development, and other data points
  • Synthesize data from formal and informal sources to understand the evolving local care system, leveraging tools such as Engage (CRM), Excel, Tableau, and available research to make data-driven decisions
  • Develop and implement business and account plans to increase visibility and awareness of screening products and maximize opportunities and sales growth
  • Lead the implementation of customer-specific engagement approaches that evaluate and address customer needs, collaborating with internal stakeholders including Medical Affairs, Marketing, and Screening Advocates
  • Inform, educate, and enable target physician and stakeholder groups about screening products and value propositions, equipping them to make informed decisions about product choices
  • Proactively drives business growth by focusing on customers with highest potential and initiating connections to uncover unmet needs and opportunities
  • Seek regular feedback from customers about their experience, service, satisfaction, and perceived value
  • Fulltime
Read More
Arrow Right
New

Director of Sales

The Director of Sales (DOS) manages the sales operations of the community. The f...
Location
Location
United States , Eau Claire
Salary
Salary:
80000.00 USD / Year
dewolfeplace.seniorlivingnearme.com Logo
Dewolfe Place
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s degree in marketing, Business, Public Relations, or related field preferred
  • Two years in marketing/sales in senior living setting preferred
  • Proficient in Microsoft Office (Word, Excel, Outlook, Power Point)
  • Experience working with sales CRM systems, tracking leads and sales activities
Job Responsibility
Job Responsibility
  • Interacts with all leads provided through multiple channels and convert those leads into residents
  • Builds customer focused relationships by advancing the lead through the sales process
  • Executes all facets of the Sales Playbook to achieve budgeted occupancy and net revenue
  • Manages the sales tracking reports and provides daily updates
  • Conducts weekly strategy and advisory meetings with the Executive Director
  • Communicates sales results to key stakeholders
  • Consistently conducts on-site walk throughs of the community
  • Plans and executes local sales events
  • Pulls management reports on sales activities, leads, move ins, conversions, and critical success factors
  • Tracks leads, keeping accurate records on all leads and prospects using a CRM
What we offer
What we offer
  • medical
  • dental
  • vision
  • life and disability insurances
  • paid time off
  • paid holidays
  • 401(k) plan with company match
  • Employee Assistance Program
  • accident insurance policies
  • Fulltime
Read More
Arrow Right
New

Director of Sales

The Director of Sales (DOS) manages the sales operations of the community. The f...
Location
Location
United States , Cedarburg
Salary
Salary:
Not provided
dewolfeplace.seniorlivingnearme.com Logo
Dewolfe Place
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s degree in marketing, Business, Public Relations, or related field preferred
  • Two years in marketing/sales in senior living setting preferred
  • Proficient in Microsoft Office (Word, Excel, Outlook, Power Point)
  • Experience working with sales CRM systems, tracking leads and sales activities
Job Responsibility
Job Responsibility
  • Interacts with all leads provided through multiple channels including advertising, public relations, referral, or personal contact and convert those leads into residents of the community using professional selling skills and our sales process
  • Builds customer focused relationships by advancing the lead through the sales process and gaining customer commitment
  • Executes all facets of the Sales Playbook (Sales System) including proper discovery, overcoming objections, and closing techniques to achieve budgeted occupancy and net revenue
  • Manages the sales tracking reports and provides daily updates and conveying all activities to the Executive Director
  • Conducts weekly strategy and advisory meetings with the Executive Director
  • Communicates sales results to key stakeholders a minimum of one week
  • Consistently conducts on-site walk throughs of the community to ensure the tour path and model rooms are ready for company
  • Plans and executes local sales events to generate and convert leads
  • Pulls management reports on sales activities, leads, move ins, conversions, and critical success factors
  • Tracks leads, keeping accurate records on all leads and prospects and all sales activities using a CRM
What we offer
What we offer
  • medical
  • dental
  • vision
  • life and disability insurances
  • paid time off
  • paid holidays
  • 401(k) plan with company match
  • Employee Assistance Program
  • accident insurance policies
  • Fulltime
Read More
Arrow Right