Senior Bioinformatics Scientist Jobs

Senior Bioinformatics Scientist

BillionToOne

Location:
United States , Menlo Park

Category:
IT - Software Development

Contract Type:
Not provided

Salary:

156060.00 - 176868.00 USD / Year

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Job Description:

We are looking for a Senior Bioinformatics Scientist to join a fast growing team. This person will be responsible for the generation, analysis, and communication of clinical next-generation DNA sequencing data for the Northstar oncology products. Our sample volume is growing extremely quickly, and this role will own the further development of our analysis pipeline to analyze tens of thousands of samples, and be the lead scientist for everything related to our bioinformatics analyses.

Job Responsibility:

Develop sophisticated and robust NGS analysis pipelines capable of processing tens of thousands of samples
Develop tests and test frameworks for NGS pipelines
Analyze and troubleshoot clinical NGS data
Analyze assay performance and contribute to publications that demonstrate the clinical validity and utility of our tests
Design new quality metrics and processes for clinical molecular diagnostic assays
Collaborate with R&D scientists to generate new scientific insights
Communicate assay performance and capabilities to clinical personnel at weekly meetings and to other non-clinical stakeholders

Requirements:

PhD in Bioinformatics, Computational Biology, Computer Science, Bioengineering, Physics or related fields
2+ years of experience developing robust and scalable bioinformatics pipelines
2+ years of experience analyzing NGS data
Fluency in Python
Experience with Linux environment, GitHub and AWS
Excellent communication and presentation skills, ability to work across functional teams and with non-experts

Nice to have:

Start-up experience
Experience working in a regulated environment
Experience with CI/CD pipelines and dockerized code deployment
Experience with cloud infrastructure management with infrastructure as code such as CDK

What we offer:

Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options
employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)
Free daily on-site lunches provided from top eateries
A variety of perks on campus (state of the art gym, restaurant)
Free on-site EV charging (compatible with all EVs, including Tesla)
Generous equity options offering
Corporate bonus program

Additional Information:

Job Posted:
December 26, 2025

Employment Type:

Fulltime

Work Type:

On-site work

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