Senior Bioinformatics Developer Job at Saphetor

Senior Bioinformatics Scientist

Job Advert: Senior Bioinformatics Scientist. Our client is an emerging leader wi...

Location

United States , San Francisco

Salary:

170000.00 - 190000.00 USD / Year

Signify Technology

Expiration Date

Until further notice

Requirements

PhD in Biological Sciences, Bioinformatics, Computational Biology, or related field, with 3+ years of experience developing production-level bioinformatics pipelines
Deep expertise in analyzing bulk/single-cell RNAseq data and performing differential gene expression using state-of-the-art tools
Significant experience building production-level Snakemake (or Nextflow) pipelines, with local and cloud-based deployments
Strong knowledge of sequence analysis (alignment, assembly) and molecular biology, with experience in Oxford Nanopore and Illumina sequencing
Proficiency in Python (numpy, pandas, Jupyter, Biopython) and package management (e.g., Conda)
Hands-on experience with Docker, Apptainer, or Singularity for containerized workflows
Expertise in Git/GitHub and Linux shell scripting for version control and automation
Proficiency in developing intuitive web tools for bioinformatics reporting (e.g., R Shiny, Streamlit)
Familiarity with public genomic data repositories (e.g., NCBI, Ensembl) and large-scale genomic data processing
Strong communication skills and ability to write clean, maintainable, production-ready code

Job Responsibility

Designing and optimizing high-performance bioinformatics pipelines for processing thousands of daily samples, leveraging tools like Snakemake and cloud deployments
Innovating sequence analysis workflows for bulk/single-cell RNAseq, differential gene expression, and large-scale genomics, ensuring robust and scalable solutions
Troubleshooting complex sequencing data challenges, from biological artifacts to platform-specific issues, to ensure reliable outputs
Developing intuitive web tools (e.g., Streamlit, R Shiny) and data visualizations to transform raw bioinformatics data into actionable insights
Providing thought leadership and mentoring junior team members, fostering a culture of innovation and collaboration
Staying ahead of industry trends, integrating emerging bioinformatics tools to enhance our offerings for biopharma and research clients

What we offer

Competitive Compensation: Highly competitive remuneration
Generous Time Off: 4 weeks paid time off + 10 paid holidays
Comprehensive Health Coverage: Health, dental, and vision insurance, plus life insurance and mental health coverage
Retirement and Wellness: 401(k) with matching, Health Advocate services, and gym membership
Impactful Work: Contribute directly to accelerating biotech research, supporting novel therapies and sustainability
Innovative Environment: Work with cutting-edge tools (e.g., Snakemake, Streamlit, AWS) and collaborate with top-tier researchers
Supportive Culture: Join a passionate, inclusive team that values creativity, mentorship, and professional growth

Fulltime

Senior C++ Developer

VarSome.com is the world’s leading website for professional human genetics. VarS...

Location

Greece , Athens

Salary:

Not provided

Saphetor

Expiration Date

Until further notice

Requirements

At least 4 years of commercial C++ development experience, using templates, STL containers, smart pointers, memory management and multithreading
BSc and/or MSc degree in Computer Science, Engineering or Mathematics
Hands-on experience with relational databases, optimizing queries and table schemas for optimal performance
Good experience with distributed cloud-based computing and big-data systems
Familiarity with agile methodologies and the ability to adapt to a fast-paced development environment, actively taking in code reviews, scrums, technical discussions etc
Very good understanding of fundamental application design principles and object-oriented design, in order to build & maintain a large high-quality code base
Excellent written & oral communication skills in English

Job Responsibility

Develop our core C++ applications and library for importing and analyzing genetic data
Write reusable, testable, and efficient code, including unit & regression tests
Take complete ownership of projects (ranging from a few days to a month) to deliver a working end-to-end implementation, including unit tests & testing
Optimize & architect our platform for maximum speed, high availability and scalability
Maintain & improve our internal high-performance clinical annotation tools and the custom databases built, optimized for genetics
Contribute to the documentation of software architecture, design and implementation details

What we offer

A position in a fascinating healthcare growth domain, at the cutting edge of technology and research
A competitive compensation package combined with additional benefits
Endless learning opportunities, while transferring new technologies from academics to clinical practice all over the world

Fulltime

Senior Bioinformatician

Location

Salary:

Not provided

Genome International Corp

Expiration Date

Until further notice

Requirements

4+ years of bioinformatics programming experience in an industry or academic setting
Demonstrated experience as scientific programmer
Very strong in Perl, Python, JAVA, C, C++, BioPerl, and shell in Linux environment
Experience in MySQL database design and development
Experience in web-based MVC application framework
Proficiency in object-oriented design and development
Experience in statistical programming using R preferably in genomics or genetic
Knowledge in Molecular biology and Biostatistics (preferable)

Job Responsibility

Collaborate with biologists to understand and document analytical and data management requirements
Clinical genetic data analysis and reporting
Conduct research, lead development of bioinformatics software tools and curated databases
Develop coherent and integrated software and databases for biological problems
Develop data-analysis strategies, write algorithms, and deploy computational tools for the exploration of large datasets
Develop bioinformatics pipelines for analyzing NGS and metabolomics data
Write programs to generate genome-wide datasets for statistical genetics
Analyze, review and modify programs to increase operating efficiency or to adapt to new requirements
Work with various technologies to develop software solutions as part of research infrastructure
Assist, collaborate, and consult with internal/external researchers on analyses of NGS data

Senior Scientist – Research Computational Biology

Join Amgen’s Mission of Serving Patients. The ARIA Computational Biology team is...

Location

United States

Salary:

143320.00 - 174539.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable]
Master’s degree and 3 years of relevant research experience
Bachelor’s degree and 5 years of relevant research experience
Strong programming skills (Python, R, Linux/Unix), familiarity with cloud computing environments, HPC, and collaborative coding practices (e.g., Git)
Track record of designing and implementing creative and holistic computational strategies to address challenging research questions
Demonstrated expertise in the analysis and interpretation of single cell omics data
Excellent presentation and communication skills to convey complex findings to diverse audiences
Self-starter with a collaborative mentality and a drive for continuous growth

Job Responsibility

Extracting biological insight from complex multi-modal omics and screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses
Developing and leveraging methods/platforms to discover, prioritize, and validate targets across diverse diseases and therapeutic modalities
Innovative research in close partnership with Amgen therapeutic area scientists, spanning both internal pipeline programs and external partnerships
Partnering with our data science and information systems teams to incorporate tools and analyses developed within ARIA Computational Biology into integrated R&D platforms

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible

Fulltime

Senior Bioinformatician - Genetics

The Sr. Bioinformatician plays a critical role in supporting clinical and resear...

Location

United States , San Diego

Salary:

119000.00 - 178000.00 USD / Year

Exact Sciences

Expiration Date

Until further notice

Requirements

PhD in bioinformatics, computational biology, computer science, or field as outlined in the essential duties
or Master’s degree plus 4 years of experience in lieu of a PhD
or Bachelor’s degree plus 6 years of experience in lieu of a PhD
5+ years of experience in bioinformatics and/or bioinformatics operations in industry or academia
3+ years in a regulated environment (e.g., medical device, IVD, biotech, or pharma)
Proficiency in Linux-based HPC or cloud computing environments
Proficiency writing custom code with the ability to adapt to commonly used languages
Expertise in NGS and genomics
Experience with statistical software (e.g., R, JMP)
Strong documentation, communication, and problem-solving skills

Job Responsibility

Lead and execute complex bioinformatics analyses across multiple platforms and studies
Diagnose and resolve pipeline errors
troubleshoot QC issues and sequencing anomalies
Develop and maintain tools for variant calling, annotation, and artifact detection, incorporating new approaches and technologies
Review and interpret intermediate and final test results, ensuring analytic performance meets regulatory standards
Perform advanced case investigations for discordant results, contamination, and false positives
Coordinate data delivery for clinical studies and clinical reporting
Stay current with industry advancements, tools, and techniques
apply innovative solutions to bioinformatics challenges
Serve as Testing Personnel under CLIA and NYS regulations

What we offer

Paid time off (including days for vacation, holidays, volunteering, and personal time)
Paid leave for parents and caregivers
A retirement savings plan
Wellness support
Health benefits including medical, prescription drug, dental, and vision coverage
Bonus eligibility

Fulltime

Senior Bioinformatics Scientist

At Boston Children’s Hospital, the quality of our care – and our inclusive hospi...

Location

United States , Boston

Salary:

83241.60 - 133192.80 USD / Year

Boston Children's Hospital

Expiration Date

Until further notice

Requirements

Bachelor’s degree in science, technology, engineering or mathematics
A minimum of one year of position-specific experience
Extensive knowledge of the use of bioinformatics computations in high-performance computing environments and web development, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, proteomics, etc.
Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters
Ability to resolve a wide range of complex Research Computing assignments in support of biomedical research
Ability to routinely lead complex projects and coordinate project teams
readiness to seek advice and guidance when needed and to operate effectively in collaboration with scientists and clinicians
ability to follow, improve and create technical documentation and standard operating procedures
Strong publication record
Ability to effectively convey messages through written communication that are tailored to target audience

Job Responsibility

Providing computational support by applying a wide range of bioinformatics tools and technologies
completing assignments independently and on time
consistently adhering to and promoting standard operating procedures and best practices
maintaining and upgrading research computing tools and technologies, migrating data, documenting changes, and adjusting internal processes
Routinely leading or participating in complex Research Computing projects with other members from the BCH research community
setting goals and objectives for projects and demonstrating achievement of those goals and objectives
coordinating work activities with other stakeholders
contributing to the resulting presentations and/or publications
Training staff and researchers
effectively tailoring presentations

What we offer

flexible schedules
affordable health, vision and dental insurance
child care and student loan subsidies
generous levels of time off
403(b) Retirement Savings plan
Pension
Tuition and certain License and Certification Reimbursement
cell phone plan discounts
discounted rates on T-passes

Fulltime

Senior Bioinformatics Scientist

The Senior Bioinformatics Scientist, with input from senior scientists and leade...

Location

United States , San Diego

Salary:

128000.00 - 192000.00 USD / Year

Exact Sciences

Expiration Date

Until further notice

Requirements

Ph.D. in bioinformatics, computational biology, computer science, mathematics, or related field
or Master’s degree in same fields plus 4 years of experience in lieu of a Ph.D.
or Bachelor’s degree in same fields plus 6 years of experience in lieu of Ph.D.
5+ years of industry or academia experience in bioinformatics
3+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry
Extensive experience in Linux-based HPC or cloud computing environments and associated tools
Ability to write custom code in at least three programming or scripting languages
Technical expert in the area of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics
Knowledge of product/assay research, design, or development
Working knowledge of statistical and mathematical methods in biology/genetics, including experience with statistical software, such as JMP or R

Job Responsibility

Conduct analyses within several product or technology areas and identify problems and discrepancies
Independently develop, plan, and analyze results of bench level experiments within several product or technology areas
effectively present and clearly communicate findings at data meetings, group meetings and project team meetings
Analyze research/experimental data, interpret the results, and provide insights into the next steps and the direction of the project
Independently develop methods and procedures for new assignments/study/experiments
Provide technical guidance to junior scientists in project teams
Manage bench-generated data and bioinformatics outputs within high performance computing (HPC) or cloud computing environment
Determine, utilize, and apply methods or technologies effectively and provide ideas for new techniques, when appropriate
Maintain knowledge of technological industry developments that could assist in completion of an assignment or aid in the development of new processes or procedures
Provide technical input and participate in decisions affecting project planning and experimental design

What we offer

Paid time off (including days for vacation, holidays, volunteering, and personal time)
Paid leave for parents and caregivers
A retirement savings plan
Wellness support
Health benefits including medical, prescription drug, dental, and vision coverage
Bonus eligibility

Fulltime

Physician Director Oncology Data Science - Translational Science

Are you looking for an opportunity to lead a Translational Data Science team wit...

Location

United States , Collegeville, Pennsylvania

Salary:

Not provided

GSK

Expiration Date

Until further notice

Requirements

medical degree
Completion of a clinical residency program leading to board qualification or certification in internal medicine, pathology, pediatrics is required
10 years plus academic or industry experience in Computational Biology, Bioinformatics, or Translational/Clinical AI with focus on Oncology
5 years of leadership or matrix leadership experience in Computational Biology, Applied AI/ML, Cancer Biology or a related field

Job Responsibility

Lead and build a growing team of Translational Data Scientists to support and innovate the Oncology portfolio pipeline
Leverage your clinical training and experience to translate complex computational and molecular insights into clinically meaningful hypotheses, study designs, and biomarker strategies that directly inform patient care and oncology clinical development
Contribute scientific expertise and design to multiple drug discovery or development efforts across oncology
Act as a competent and recognized expert in developing and critiquing the scientific validity of research/development initiatives to drive the development and delivery of long-term scientific strategy in Oncology Genomics
Individually contribute with analyses and integration of complex cancer datasets. This includes analysis of histopathology imaging data, gene & protein expression (bulk + single cell + spatial), somatic mutations, copy number alterations, and structural variants
Apply statistical methods and AI/machine learning algorithms to identify patterns in data, predict drug response, and discover potential biomarkers. Critically evaluate results. Conduct survival analysis to assess the impact of various factors on patient outcomes
Lead the development and use of bioinformatics pipelines
Serve as a recognized leader in driving technological foresight within specific scientific function or directing content of programs
Lead and influence the outcome of multidisciplinary meetings including partners in therapeutic research units, translational and clinical development teams.
Communicate complex scientific findings clearly to both technical and non-technical audiences.

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

Senior Bioinformatics Developer

Saphetor

Location:

Category:
IT - Software Development

Contract Type:
Employment contract, B2B

Salary:

Job Description:

Job Responsibility:

Requirements:

Nice to have:

Additional Information:

Job Posted:
March 03, 2026

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