Senior Bioinformatics Developer Job at Saphetor

Senior Bioinformatics Scientist

At Boston Children’s Hospital, the quality of our care – and our inclusive hospi...

Location

United States , Boston

Salary:

83241.60 - 133192.80 USD / Year

Boston Children's Hospital

Expiration Date

Until further notice

Requirements

Bachelor’s degree in science, technology, engineering or mathematics
A minimum of one year of position-specific experience
Extensive knowledge of the use of bioinformatics computations in high-performance computing environments and web development, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, proteomics, etc.
Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters
Ability to resolve a wide range of complex Research Computing assignments in support of biomedical research
Ability to routinely lead complex projects and coordinate project teams
readiness to seek advice and guidance when needed and to operate effectively in collaboration with scientists and clinicians
ability to follow, improve and create technical documentation and standard operating procedures
Strong publication record
Ability to effectively convey messages through written communication that are tailored to target audience

Job Responsibility

Providing computational support by applying a wide range of bioinformatics tools and technologies
completing assignments independently and on time
consistently adhering to and promoting standard operating procedures and best practices
maintaining and upgrading research computing tools and technologies, migrating data, documenting changes, and adjusting internal processes
Routinely leading or participating in complex Research Computing projects with other members from the BCH research community
setting goals and objectives for projects and demonstrating achievement of those goals and objectives
coordinating work activities with other stakeholders
contributing to the resulting presentations and/or publications
Training staff and researchers
effectively tailoring presentations

What we offer

flexible schedules
affordable health, vision and dental insurance
child care and student loan subsidies
generous levels of time off
403(b) Retirement Savings plan
Pension
Tuition and certain License and Certification Reimbursement
cell phone plan discounts
discounted rates on T-passes

Fulltime

Senior Bioinformatics Scientist

The Senior Bioinformatics Scientist, with input from senior scientists and leade...

Location

United States , San Diego

Salary:

128000.00 - 192000.00 USD / Year

Exact Sciences

Expiration Date

Until further notice

Requirements

Ph.D. in bioinformatics, computational biology, computer science, mathematics, or related field
or Master’s degree in same fields plus 4 years of experience in lieu of a Ph.D.
or Bachelor’s degree in same fields plus 6 years of experience in lieu of Ph.D.
5+ years of industry or academia experience in bioinformatics
3+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry
Extensive experience in Linux-based HPC or cloud computing environments and associated tools
Ability to write custom code in at least three programming or scripting languages
Technical expert in the area of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics
Knowledge of product/assay research, design, or development
Working knowledge of statistical and mathematical methods in biology/genetics, including experience with statistical software, such as JMP or R

Job Responsibility

Conduct analyses within several product or technology areas and identify problems and discrepancies
Independently develop, plan, and analyze results of bench level experiments within several product or technology areas
effectively present and clearly communicate findings at data meetings, group meetings and project team meetings
Analyze research/experimental data, interpret the results, and provide insights into the next steps and the direction of the project
Independently develop methods and procedures for new assignments/study/experiments
Provide technical guidance to junior scientists in project teams
Manage bench-generated data and bioinformatics outputs within high performance computing (HPC) or cloud computing environment
Determine, utilize, and apply methods or technologies effectively and provide ideas for new techniques, when appropriate
Maintain knowledge of technological industry developments that could assist in completion of an assignment or aid in the development of new processes or procedures
Provide technical input and participate in decisions affecting project planning and experimental design

What we offer

Paid time off (including days for vacation, holidays, volunteering, and personal time)
Paid leave for parents and caregivers
A retirement savings plan
Wellness support
Health benefits including medical, prescription drug, dental, and vision coverage
Bonus eligibility

Fulltime

Senior Bioinformatics Scientist

Job Advert: Senior Bioinformatics Scientist. Our client is an emerging leader wi...

Location

United States , San Francisco

Salary:

170000.00 - 190000.00 USD / Year

Signify Technology

Expiration Date

Until further notice

Requirements

PhD in Biological Sciences, Bioinformatics, Computational Biology, or related field, with 3+ years of experience developing production-level bioinformatics pipelines
Deep expertise in analyzing bulk/single-cell RNAseq data and performing differential gene expression using state-of-the-art tools
Significant experience building production-level Snakemake (or Nextflow) pipelines, with local and cloud-based deployments
Strong knowledge of sequence analysis (alignment, assembly) and molecular biology, with experience in Oxford Nanopore and Illumina sequencing
Proficiency in Python (numpy, pandas, Jupyter, Biopython) and package management (e.g., Conda)
Hands-on experience with Docker, Apptainer, or Singularity for containerized workflows
Expertise in Git/GitHub and Linux shell scripting for version control and automation
Proficiency in developing intuitive web tools for bioinformatics reporting (e.g., R Shiny, Streamlit)
Familiarity with public genomic data repositories (e.g., NCBI, Ensembl) and large-scale genomic data processing
Strong communication skills and ability to write clean, maintainable, production-ready code

Job Responsibility

Designing and optimizing high-performance bioinformatics pipelines for processing thousands of daily samples, leveraging tools like Snakemake and cloud deployments
Innovating sequence analysis workflows for bulk/single-cell RNAseq, differential gene expression, and large-scale genomics, ensuring robust and scalable solutions
Troubleshooting complex sequencing data challenges, from biological artifacts to platform-specific issues, to ensure reliable outputs
Developing intuitive web tools (e.g., Streamlit, R Shiny) and data visualizations to transform raw bioinformatics data into actionable insights
Providing thought leadership and mentoring junior team members, fostering a culture of innovation and collaboration
Staying ahead of industry trends, integrating emerging bioinformatics tools to enhance our offerings for biopharma and research clients

What we offer

Competitive Compensation: Highly competitive remuneration
Generous Time Off: 4 weeks paid time off + 10 paid holidays
Comprehensive Health Coverage: Health, dental, and vision insurance, plus life insurance and mental health coverage
Retirement and Wellness: 401(k) with matching, Health Advocate services, and gym membership
Impactful Work: Contribute directly to accelerating biotech research, supporting novel therapies and sustainability
Innovative Environment: Work with cutting-edge tools (e.g., Snakemake, Streamlit, AWS) and collaborate with top-tier researchers
Supportive Culture: Join a passionate, inclusive team that values creativity, mentorship, and professional growth

Fulltime

Senior C++ Developer

VarSome.com is the world’s leading website for professional human genetics. VarS...

Location

Greece , Athens

Salary:

Not provided

Saphetor

Expiration Date

Until further notice

Requirements

At least 4 years of commercial C++ development experience, using templates, STL containers, smart pointers, memory management and multithreading
BSc and/or MSc degree in Computer Science, Engineering or Mathematics
Hands-on experience with relational databases, optimizing queries and table schemas for optimal performance
Good experience with distributed cloud-based computing and big-data systems
Familiarity with agile methodologies and the ability to adapt to a fast-paced development environment, actively taking in code reviews, scrums, technical discussions etc
Very good understanding of fundamental application design principles and object-oriented design, in order to build & maintain a large high-quality code base
Excellent written & oral communication skills in English

Job Responsibility

Develop our core C++ applications and library for importing and analyzing genetic data
Write reusable, testable, and efficient code, including unit & regression tests
Take complete ownership of projects (ranging from a few days to a month) to deliver a working end-to-end implementation, including unit tests & testing
Optimize & architect our platform for maximum speed, high availability and scalability
Maintain & improve our internal high-performance clinical annotation tools and the custom databases built, optimized for genetics
Contribute to the documentation of software architecture, design and implementation details

What we offer

A position in a fascinating healthcare growth domain, at the cutting edge of technology and research
A competitive compensation package combined with additional benefits
Endless learning opportunities, while transferring new technologies from academics to clinical practice all over the world

Fulltime

Senior FAS - NGS + Proteomics

Our client is launching a novel platform, providing integrated analysis of genom...

Location

United States

Salary:

Not provided

AchieveBio

Expiration Date

Until further notice

Requirements

PhD in Genomics, Biochemistry, Immunology or related Life Science discipline (or MS with 5+ years industry bench experience)
Minimum of 3 years Field Application Scientist experience
Hands-on experience with NGS workflows, including library prep, sequencing platforms, and basic data interpretation
Technical understanding of immunoassays, assay development and antibody troubleshooting
Familiarity with bioinformatics and data visualization platforms
Demonstrated experience contributing to scientific collateral, such as application notes
Excellent communication, presentation and troubleshooting skills
Demonstrated leadership and mentoring skills

Job Responsibility

Serve as scientific expert for customers and internal teams, combining strong technical knowledge of NGS and immunoassays
Assist with method development during pre-launch, and provide advanced technical support upon commercialization
Identify and collaborate with customers in the beta testing stage
Develop hands-on proficiency with the platform, working closely with R&D and Product Development teams prior to commercialization
Capture VOC feedback internally for product and documentation improvements
Provide pre- and post-sales scientific support including product demonstrations, technical presentations and training/troubleshooting of experimental design, complex assay challenges, workflow issues and data interpretation involving both NGS and immunoassays
Create customer-facing content, including training materials, slide decks, application notes, workflow diagrams and troubleshooting resources
Represent company at scientific conferences and seminars
Train and mentor other FAS as the team expands
Travel to customer sites and conferences approximately 50% of the time

What we offer

Competitive salary
bonus
car allowance
excellent benefits

Fulltime

Senior Director Translational Data Sciences

We are seeking an exceptional and ambitious scientific leader to serve as Senior...

Location

United Kingdom; Germany; United States , Stevenage; Heidelberg; Collegeville

Salary:

Not provided

GSK

Expiration Date

Until further notice

Requirements

Physical sciences (Maths, Computer Science, Physics, Chemistry, Engineering etc) or Biological sciences (Biology, Biochemistry, Bioengineering etc) undergraduate degree or Medical degree
PhD in data science, computer science, computational biology, bioinformatics, or a closely related discipline
Extensive experience spanning academic and industrial drug discovery environments, with a demonstrable record of leading high-impact computational biology programmes from conception through to application to drug discovery or development challenges
Prior line management experience and experience building and leading interdisciplinary teams across computational, experimental, and translational disciplines in both academic and industrial settings
Demonstrated experience structuring and managing strategic partnerships with academic institutions and companies, including contribution to alliance governance
Familiarity with the translational interface between target biology and clinical development
experience with adaptive clinical trial design and biomarker-driven patient stratification is highly desirable
Experience presenting to executive leadership, external partners, and international scientific audiences

Job Responsibility

Scientific Strategy: Develop and execute the Translational Data Sciences strategy, with accountability for portfolio-level outcomes across multiple therapeutic areas including respiratory, renal, hepatology, and immune-mediated disease
Data Sciences and AI: Leverage the potential of data sciences for pipeline progress through team leadership, collaboration across Translational & Developmental Sciences and application across therapy areas and the broader organisations across GSK including R&D Technologies and AIML
Partnership & Alliance Leadership: Establish and maintain high-value partnerships with leading academic laboratories, companies, and international consortia
Translational Integration: Work directly with R&D leadership to align computational strategy with clinical development priorities
Team Leadership: Build and mentor an interdisciplinary team of computational biologists, AI/ML engineers, and clinician-scientists and wet-lab scientists
Scientific Visibility: Contribute to the organisation's external positioning through publications, conference presentations, and academic collaborations

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

Senior Scientist - Target Discovery & Validation – Induced Proximity Platform (IPP)

At Amgen, if you feel like you're part of something bigger, it's because you are...

Location

Canada , Burnaby

Salary:

115503.10 - 156268.90 CAD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree or Master's degree and 2 years of relevant scientific experience or Bachelor's degree and 4 years of relevant scientific experience

Job Responsibility

Design, implement, and execute complex experimental workflows to profile and validate cell surface proteins
Lead and support cell surface-based target discovery and validation projects using in vitro models (cell lines, primary cells, tissues, etc.)
Apply proximity labeling, cell surface enrichment, and related proteomics efforts for target validation and nomination studies
Support target functionalization efforts toward developing multispecific antibody therapeutics, and perform efficacy, mechanism of action (MoA) and drug response studies for these therapeutics
Use cutting-edge software tools and collaborate with bioinformatics to analyze and interpret target discovery proteomics datasets
Collaborate across multidisciplinary teams to drive integrated target discovery, validation and functionalization efforts
Present findings internally and externally through team meetings, conferences, and peer-reviewed publications
Maintain detailed electronic lab notebooks and experimental records

Fulltime

Senior Data Engineer

ADC is a European data and AI consultancy with offices in the Netherlands, Swede...

Location

Denmark , København

Salary:

Not provided

Life Science Talent

Expiration Date

Until further notice

Requirements

4+ years of experience in Life Sciences industry as a Data Engineer, ideally gained in consulting or project-based work
A solid foundation in AWS/Azure, Databricks, Python, data modelling, testing and monitoring in production environments
Hands-on experience developing data pipelines for omics data, imaging data, or other scientific datasets
A quantitative academic background: Bioinformatics or similar fields
The ability to communicate with anyone in the room, breaking down complex ideas for technical and non-technical audiences
A proactive and entrepreneurial mindset: you’re eager to solve problems, innovate, and drive change
A collaborative spirit: You believe the best solutions come from diverse perspectives and supporting each other to raise the bar
Ability to work at the intersection of science, engineering, and business
Fluency in English

Job Responsibility

Design, build, and maintain scalable data pipelines for Life Science use cases such as omics, imaging, experimental, and clinical data
Work with complex, high-volume, and heterogeneous datasets, ensuring data quality, traceability, and reproducibility
Develop data solutions on cloud platforms (AWS and/or Azure) that follow modern engineering and security best practices
Contribute to and implement solutions using Databricks and modern data engineering frameworks
Support projects end-to-end, from early discovery and design through to production deployment
Collaborate closely with bioinformaticians, data scientists, AI engineers, and client stakeholders to co-create solutions that work in practice
Share knowledge internally and contribute to ADC's thought leadership in Life Sciences data and AI

What we offer

Impact you can point to: You’ll see your work in action and our projects change how organisations make decisions
Real responsibility, real support: You’ll work alongside experienced experts from the start, learning by doing with mentorship and feedback built in
The freedom to try new things: Spot a better way to build something? A smarter process? We want people who challenge the status quo
Collective Week: Once a year, we go on a workation with the whole ADC team. We work on pro bono projects, explore new ideas, and make the kind of memories you’ll want to talk about
Ownership opportunities: We offer a competitive salary and bonus structure, plus the opportunity to invest in the company and become a co-owner once specific conditions are met. We mean it when we say collective
A vibrant culture: Friday breakfast, sports, social events, and much more: a culture you’ll notice from day one

Fulltime

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Senior Bioinformatics Developer

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