Scientist - Small Molecule Technology

• Develop safe, robust, scalable, and efficient manufacturing processes for intermediate and Active Pharmaceutical Ingredients (APIs) suitable for both pilot plant and commercial scale production
• Performing literature search and identifying various synthetic routes for process development
• Promotes the use of novel experimental approaches within sub-function
• routinely investigates/creates innovative processes, hypotheses and methodologies
• Knowledge of interpretation of structures using spectral techniques like NMR, IR & Mass spectra
• Planning and Performing experiments as per process governance (Lab feasibility, Optimization, Pre-validation, CPP and Validation)
• Performing What if studies, stress studies, holding time studies, Mass balance, recovery studies and scale up studies
• Encountering the process challenges on time and supporting production teams for scale up activities
• Handling of business critical / supply chain critical related investigational projects on fast track
• Participate in brainstorming activity for the project in identifying scope of improvement
• Responsible for making necessary scientific statutory documents for the lab execution of a given project
• Designing experiments based on the project /business requirement in varying scale as per the needs
• Perform data analysis, interpret the data of them and provide scientific rationale for the experiments
• Support the next level manager in providing the cost estimates associated with R&D project proposals
• Summarize the experimental results and present to the next level managers for discussion
• Prepare Technical project updates with precious data as per the business meeting requirement regularly
• Knowledge on ICH guidelines
• Co-ordinate with Analytical, Process safety, Process engineering teams on the project discussions and support the need of them to drive the project
• Utilization of electronics tools (Biovia eLN, GDMS, LIMS etc.,)
• Partner closely with other CRD scientists, Process Engineers, Process Safety Chemists, Crystallization Technologists, Pilot Plant facility, Analytical, Formulation and manufacturing colleagues at Global Pfizer sites as required
• Responsible for instrument qualification across the CRD labs (coordination with instrumentation team, quality team)
• Ensure compliance with cGMP /GSP procedures and practices
• Ensure effective safety systems are implemented in the premises
• Perform other tasks as per the dynamic business requirement

• Ph.D in the field of Organic Chemistry
• Demonstrated capabilities and experience in performing chemical reactions, structure characterizations, basic understanding of chromatography, Crystallizations, Basic safety principles, Basic quality principles, basic understanding of analytical techniques
• Experience and demonstrated competencies in working with teams in a matrixed organization, building and nurturing relationships and effective engagement resulting in successful outcomes
• Candidate should have skill in preparing the technical reports and adherence to compliance.

Willingness to learn and apply new technology/ tools to meet process / business needs