Scientist - Oncology Job at Amgen (South San Francisco)

Associate Scientist - Oncology

Amgen Oncology Research is seeking an Associate Scientist who supports our T cel...

Location

United States , South San Francisco

Salary:

98299.10 - 132992.90 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Master's Degree
Bachelor's Degree and 2+ years of relevant experience
Associate's degree and 4 years of relevant experience
High school diploma / GED and 6 years of relevant experience

Job Responsibility

Support preclinical pipeline programs by performing assays and delivering scientific evidence of drug candidates in a timely manner
Operate and maintain standard lab equipment
Maintain organized laboratory notebooks and repositories
Interact closely with cross-functional team
Support publication and presentation at scientific conferences

What we offer

Comprehensive employee benefits package including Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
Discretionary annual bonus program
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible

Fulltime

Director, Clinical Research Scientist Oncology

Turn scientific insight into life-changing oncology therapies through clinical l...

Location

United States , Wilmington

Salary:

Not provided

Proclinical

Expiration Date

Until further notice

Requirements

Degree in a scientific/life sciences field
Pharm.D. or Ph.D. preferred.
Minimum of 8 years of experience in oncology research or related field.
Demonstrated experience leading clinical development programs in oncology (preferably late-stage).
Experience with global regulatory interactions and submissions (FDA, EMA, or other agencies).
Strong understanding of oncology clinical endpoints, trial design, and statistical considerations.
Proven ability to work effectively in a cross-functional matrix environment and influence without direct authority.
Track record of scientific publications and/or conference presentations.
Excellent written and oral communication skills.
Strong analytical and scientific writing skills.

Job Responsibility

Collaborate with physicians, clinical scientists, and cross-functional teams to support oncology clinical development, focusing on protocol development and study start-up activities.
Development of protocols for clinical studies.
Preparation of clinical development plans.
Drafting of clinical scientific documents such as IND, IND amendments, Investigator's Brochures, Annual Reports and other FDA submissions.
Monitor, perform data review, and summarize safety and efficacy data in ongoing studies.
Assist with study design for exploratory development.
Lead the clinical matrix teams for assigned compounds.
Represent exploratory development on project teams.
Develop relationships with appropriate consultants.
Write abstracts and present data at scientific meetings, both internally and externally.

Fulltime

Director, Global Real-World Evidence & Health Outcomes Scientist, Oncology

For drugs to be successful, there must be robust health outcomes data to support...

Location

United States , Philadelphia

Salary:

204000.00 - 340000.00 USD / Year

GSK

Expiration Date

Until further notice

Requirements

MSc, or equivalent in health outcomes, health economics, epidemiology, pharmacy, health or life sciences
3+ years of experience working in the pharmaceutical industry, preferably in a multi-national company
Experience in planning and delivering individual projects, managing budgets and working within a matrix setting
A history of designing a variety of RWE studies including prospective observational studies, cross-sectional and retrospective cohort studies, chart reviews, and database analyses
Proficiency in utilizing evidence for the development of HTA submissions, reimbursement and/or medical engagements
A track record of delivering robust payer evidence and credibility to engage meaningfully with external experts and leaders in the field
Expertise with the diversity and complexity of healthcare markets, health technology assessment agencies, and reimbursement decision making globally, in region and local markets
Experience in communicating technical and complex concepts and results to various audiences to impact decision-making
Experience in oncology.

Job Responsibility

Plan, design and execute multiple studies for a given asset and manage timelines, deliverables, and budget
Assure quality of deliverables, including review and sign off project specifications, protocols, data analysis plans, final study reports, abstracts, posters and manuscripts, in adherence to SOPs
Identify resources, references and analyses to inform scientific design and advise internal experts.(medical affairs, clinical, commercial/market access) and external experts as needed in support of the asset team
Translate needs for evidence into study concepts in alignment with strategic objectives and vision for the asset, e.g. development of study protocols and proposing innovative and cost-effective ways of developing and executing studies
Develop and maintain a good working knowledge of real-world data resources, existing partnerships and public initiatives and become the point person for select sources to advise on their suitability to address given research questions
Develop a deep understanding of customers’ needs, including clinicians and HTA requirements, and their acceptance of different types of evidence and impact of that evidence to their decision making
Collaborate with internal teams and participate in best practice sharing sessions across the non-interventional study organization
Build strong working relationships with stakeholder groups across medical, market access, R&D and commercial to ensure strategic alignment and optimal cross-functional collaboration and communication
Ensure key stakeholders, including TA aligned business leaders, are regularly updated on plans through periodic reporting
Develop excellent working relationships with external thought leaders to ensure appropriate methods and research agendas are applied, in accordance with GSK policies.

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes
Health care and other insurance benefits (for employee and family)
Retirement benefits
Paid holidays
Vacation

Fulltime

Clinical Genomics Scientist, Oncology

Join a team of brilliant, passionate innovators who wake up every day determined...

Location

United States

Salary:

100.00 USD / Hour

BillionToOne

Expiration Date

Until further notice

Requirements

Ph.D. in Human Genetics, M.S. in Genetic Counseling, or related field
2+ years of experience in somatic variant interpretation based on ACMG/AMP guidelines in a clinical setting (alternatively, 1+ years of germline variant interpretation and 1+ years of somatic variant interpretation experience)
Hands-on experience working with human mutation databases (COSMIC, ClinVar, OncoKB), functional annotation sources (dbSNP), and genome browsers (UCSC)
Familiarity with IGV and BAM file analysis and data-minded willingness to learn to use basic bioinformatics tools, with technically minded insights
Knowledge of cancer somatic mutation and signaling pathways (e.g., which mutations have FDA approved drugs, Phase II/III clinical trials, which mutations are considered “hot targets” for drug development, etc.)
Exceptional attention to detail to follow highly detailed SOPs and strong organizational skills to track and manage clinical reporting and product improvement projects
Excellent communication skills and ability to work collaboratively with cross-functional teams
Ability to work on Saturday and/or Sunday, in addition to hours during the week.

Job Responsibility

Somatic variant interpretation and data review: Perform somatic-based variant interpretation, diving into the literature and databases to classify variants and match treatments for reporting, performing verification as required with BAM file analysis
Clinical report drafting: Carefully draft reports for each requisition primarily using in-house reporting API, working closely with the engineering and QA teams on reporting, and the laboratory directors on report language
Content curation: Contribute to curation of gene-level content such as domain and critical residue curation
Contribute to oncology R&D: Work closely with the R&D team to help with somatic oncology based projects, providing expertise on variant interpretation, biological pathways/mechanisms, and other gene/variant-level reviews and analyses.

What we offer

Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
The ability to indirectly or directly change the lives of hundreds of thousands patients

Parttime

Senior Manager, MED Oncology RWE/Epi Scientist

The Senior Manager, Oncology, position within Medical Evidence Development (MED)...

Location

United Kingdom , Walton Oaks

Salary:

Not provided

Pfizer

Expiration Date

Until further notice

Requirements

PhD in Epidemiology, Statistics/Biostatistics, Health Outcomes Research, Quantitative Methods, Public Health, Health Economics, or Other Biological Science fields with a substantial quantitative component and at least 1 years of relevant experience in the pharmaceutical, academic and/or medical environment
or, MPH or another relevant Master’s degree and at least 5 years of experience in the pharmaceutical, academic and/or medical environment, at least 1 of which were in the pharmaceutical industry
Demonstrated strong quantitative skills and methods expertise to generate rapid insights from real-world / observational data source
Demonstrated strong technical writing skills and oral presentation skills with a track-record of publishing in peer-reviewed journals and presenting at medical/scientific conferences
Demonstrated ability to convert complex analysis into meaningful insights with data visualization and presentation tools and able to manipulate and analyze complex structured and unstructured data from multiple real world evidence sources
Ability to work under pressure with a high level of autonomy/leadership on research projects and collaborate with multiple partners in a matrixed environment
Knowledgeable of the external regulatory environment for real-world evidence and maintains awareness of scientific developments in epidemiology, medicine, and technology (e.g., artificial intelligence)

Job Responsibility

Synthesizing the literature and contributing to the design, conduct and reporting of global epidemiologic research studies on Pfizer I&I products
Accountable for the quality, timeliness, and efficiency of all RWE/Epi deliverables in assigned product/disease area
Maintain an internal network of Pfizer stakeholders to cultivate innovation, cross-functional collaboration, and identify new opportunities for RWE/Epi to increase the value of Pfizer assets
Develop external partnerships to leverage data resources and collaboration on high priority global studies
Authoring and reviewing study protocols, reports, and presentations, as well as communication in writing and presentations to internal stakeholders, regulatory authorities, and medical professionals
Responsible for non-study deliverables such as RWE insights, epidemiology literature reviews, regulatory responses, and department initiatives
Identifying, designing and supporting or leading real-world evidence studies of disease epidemiology and effectiveness as part of the global cross-functional Integrated Evidence Plan
Maintain knowledge and awareness of internal and external data resources and identify appropriate studies for addressing questions of interest
Partner with Chief Medical Office colleagues to address asset team evidence needs and support global regulatory submissions to the FDA, EMA and other agencies
Deliver rapid insights from real-world, observational data source

Fulltime

Senior Scientist - Hematology & Medical Oncology

The Senior Scientist provides scientific and technical leadership in the managem...

Location

United States , New York

Salary:

58661.00 USD / Year

Mount Sinai Health System

Expiration Date

Until further notice

Requirements

Ph.D in sciences or related field
Minimum five years of experience with scientific investigation
Must have demonstrated outstanding achievement in a field of research
Must have contributed to a number of peer-reviewed publications, inventions or the like, at least some of which have had a major impact on advancing the field or discipline
Prior experience successfully securing external grant funding is highly desirable

Job Responsibility

Designs and conducts complex clinical research studies requiring the determination and evaluation of alternative methods, diagnosis and treatment
Analyzes and interprets clinical data from research studies
Explores subject area and defines scope and selection of problems for investigation through conceptually related studies
Develops hypotheses to be tested and methodology for evaluating results
Communicates research results to the scientific community via published papers
Coordinates seminars and discussions for dissemination of knowledge and results of research in order to develop new diagnosis or treatment
Develops new proposals for research and obtain support for new and/ or continuing research activities
Makes decisions and recommendations that have a major impact on extensive scientific research activities
May supervise graduate/ medical students and trainees
Performs other related duties

Clinical Scientist Director - Late Development Oncology

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part...

Location

Portugal , Lisbon

Salary:

105822.45 - 143171.55 EUR / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree and 4 years of life sciences/healthcare experience
Master’s degree and 7 years of life sciences/healthcare experience
Bachelor’s degree and 9 years of life sciences/healthcare experience

Job Responsibility

Serve as a clinical and scientific subject-matter expert for the assigned therapeutic area and disease indication, with a strong focus on protocol execution and data integrity
Contribute to medical monitoring activities and support ongoing assessment of subject-level clinical data to identify trends, risks, and emerging issues
Present information internally and externally, anticipating and actively managing problems across a broad spectrum of cross-functional teams
Provide guidance and assistance in the identification and management of collaborators, consultants, and/or Clinical Research Organizations (CROs) in completion of key projects
Work cross functionally to ensure clinical strategy is translated into the development of the study concept document, study protocol, and related documents
Ensure integrity of protocols and/or components of clinical plans and for the delivery of final protocol and its governance approval
Provide clinical input into & implementation of clinical trial(s), delivery, clinical data review, and interpretation of results
Review and analyze clinical trial data to ensure accuracy, completeness, and adherence to protocol and regulatory requirements
Conduct thorough data quality assessments in the context of a data monitoring plan to maintain high standards of data accuracy and integrity throughout the trial lifecycle

What we offer

health and welfare plans for staff and eligible dependents
financial plans with opportunities to save towards retirement or other goals
work/life balance
career development opportunities
Comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
Discretionary annual bonus program
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models including remote and hybrid work arrangements where possible

Fulltime

Clinical Scientist Director - Late Development Oncology

Join Amgen's Mission of Serving Patients. At Amgen, if you feel like you're part...

Location

Portugal , Lisbon

Salary:

105822.45 - 143171.55 EUR / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree and 4 years of life sciences/healthcare experience OR Master's degree and 7 years of life sciences/healthcare experience OR Bachelor's degree and 9 years of life sciences/healthcare experience

Job Responsibility

Serve as a clinical and scientific subject-matter expert for the assigned therapeutic area and disease indication, with a strong focus on protocol execution and data integrity
Contribute to medical monitoring activities and support ongoing assessment of subject-level clinical data to identify trends, risks, and emerging issues
Present information internally and externally, anticipating and actively managing problems across a broad spectrum of cross-functional teams
Provide guidance and assistance in the identification and management of collaborators, consultants, and/or Clinical Research Organizations (CROs) in completion of key projects
Work cross functionally to ensure clinical strategy is translated into the development of the study concept document, study protocol, and related documents
Ensure integrity of protocols and/or components of clinical plans and for the delivery of final protocol and its governance approval
Provide clinical input into & implementation of clinical trial(s), delivery, clinical data review, and interpretation of results
Review and analyze clinical trial data to ensure accuracy, completeness, and adherence to protocol and regulatory requirements
Conduct thorough data quality assessments in the context of a data monitoring plan to maintain high standards of data accuracy and integrity throughout the trial lifecycle

What we offer

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
Discretionary annual bonus program
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible

Fulltime

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Scientist - Oncology

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