Scientist, Molecular Biology Job at Breega (Paris)

Scientist – Molecular Biology & Pharmacology

Join Amgen’s Mission of Serving Patients. In this vital role you will be respons...

Location

United States , South San Francisco

Salary:

131874.00 - 160907.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree
OR Master’s degree and 2 years of Molecular Biology and Pharmacology experience
OR Bachelor’s degree and 4 years of Molecular Biology and Pharmacology experience
Expertise in quantitative pharmacology, Cytokine secretion and Phosphorylation assay
Mastery in isolating various primary cells such as different types of T and B cells
A deep and broad understanding of the development, validation & execution of a wide array of cell-based assays such as cytokine secretion, cell migration, etc.
Demonstrated ability to develop and implement cellular assays for target validation, hit identification, and lead optimization, such as MesoScale Discovery, HiBIT, NanoBRET, and cell reporter assays
Familiarity with Luminex Multiplex assay, and proficiency in Flow Cytometry
Highly skilled in the development & implementation of robust, automated, 384 or 1536-well plate-based assays using a wide range of detection methods (e.g., spectrophotometry, radiometry, luminescence, fluorescence)
Experience with microplate readers and automated liquid handling systems (e.g., PerkinElmer Envision, Labcyte Echo, Agilent Bravo, etc.)

Job Responsibility

Develop and optimize Primary cell-based assays to support HTS, hits validation, and lead optimization for novel therapeutic targets
Develop and execute cell-based assays to assess the effects of small molecules on cellular pathways, receptor activity, and phenotypic outcomes
Evaluate and implement new technologies to enhance screen capabilities and assay performance
Stay current with scientific literature and industry trends related to assay technologies, novel drug modalities, and drug discovery
Represent department in multi-disciplinary project teams to present research results and provide scientific and technical support
Collaborate with internal cross-functional teams and external partners to enable project progression

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans

Fulltime

Research Scientist, Cell and Molecular Biology

Research Scientist specializing in Cell and Molecular Biology to contribute to c...

Location

United States , Wilmington

Salary:

Not provided

Proclinical

Expiration Date

Until further notice

Requirements

Degree in molecular biology, stem cell biology, or a related field (Bachelor's with relevant experience or Master's with industry experience)
Proven expertise in developing and optimizing functional cellular assays for proliferation, differentiation, and apoptosis in biologically relevant models
Strong theoretical and practical knowledge of primary stem cells
experience in hematopoietic stem cell biology or myeloid malignancies (e.g., MPN, MDS, AML) is highly preferred
Proficiency in molecular and cellular biology techniques such as ELISA, MSD-based assays, Western blotting, multicolor flow cytometry, and CRISPR-Cas9 gene-editing platforms

Job Responsibility

Design, execute, and interpret experiments using chemical and genetic approaches with scientific independence
Develop and utilize disease-relevant preclinical models to explore target biology and address complex hypotheses
Support small- and large-molecule screening efforts, ensuring data quality and translational relevance
Collaborate with internal teams across drug discovery functions to achieve shared objectives
Adapt and acquire new skills and competencies as required by project needs
Communicate complex scientific findings effectively to both internal and external audiences

Medical Laboratory Scientist Molecular Microbiology and Special Chemistry

The Medical Lab Scientist provides comprehensive laboratory testing for patients...

Location

United States , Kansas City

Salary:

Not provided

The University of Kansas Health System

Expiration Date

Until further notice

Requirements

Bachelor of Science Biological, Physical, Chemical or Clinical Laboratory Science / Medical Technology from an accredited institution
High School Graduate
Medical Laboratory Scientist (MLS) - American Society for Clinical Pathology Board of Certification (ASCP), AMT or equivalent or eligible (must be completed within 6 months of hire) within 180 Days
Meets the CLIA requirements for high complexity testing.

Job Responsibility

Analyzes patient, control and proficiency testing specimens and records results in a timely manner
Calibrates, maintains, operates and troubleshoots instrumentation issues and completes appropriate documentation
Completes continuing education and submits appropriate documentation
Follows regulatory, accreditation, safety and hospital standards, policies and procedures
Instructs, orients and mentors students, employees, residents, patients and other health care providers
Maintains an adequate inventory of all supplies
Accurately prepares, labels and stores reagents, standards, controls and specimens for analysis
Participates in quality assurance and quality improvement activities
Performs phlebotomy and sample collection as applicable
Reviews and correlates results of laboratory tests to each other and with the patient's condition, recognizing abnormal results and critical/alert values

Fulltime

Associate Scientist - Molecular Discovery

Pfizer BioMedicine Design group at San Diego, CA is seeking an outstanding and h...

Location

United States , La Jolla

Salary:

60200.00 - 97500.00 USD / Year

Pfizer

Expiration Date

Until further notice

Requirements

B.S or M.S in Biological Science (Molecular Biology, Structural Biology, Biochemistry, Cell Biology) or a related field (Chemistry, Chemical Engineering, Biomedical Engineering and Biological Engineering)
B.S or M.S with 0-2 years of relevant experience in either an academic or industrial setting
Familiar with tissue-culture sterile techniques and mammalian cell culture
Understand principles and able to execute modern molecular biology techniques, preferred in antibody engineering field
Understand principles and able to execute modern protein purification techniques, preferred in antibody engineering field
Detail-oriented, document data and experiments properly, good communication and interpersonal skills
Ability and desire to work in a fast-paced interdisciplinary scientific team and the desire to learn new techniques
Strong time management skills and ability to manage multiple projects at the same time

Job Responsibility

Work within a team on various antibody identification, optimization, and/or production projects in parallel
Maintain mammalian cell culture and execute various transient expression methods
Implement molecular biology methods such as reformatting scFv to IgG and other modalities
Implement protein purification methods to isolate IgG, fusion proteins and antigens from mammalian cell culture
Analyze proteins using standard protein characterization methods
Design experiments, analyze data, and troubleshoot when issues arise, under supervision
Present experimental design and results at internal meetings
Accomplish goals under project team timelines

What we offer

401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
paid vacation, holiday and personal days
paid caregiver/parental and medical leave
health benefits to include medical, prescription drug, dental and vision coverage
bonus target of 7.5% of the base salary
Relocation assistance may be available

Fulltime

Biology Scientist 2

We are looking for a highly motivated Scientist II to support research and devel...

Location

United States , San Diego

Salary:

Not provided

MillenniumSoft Inc

Expiration Date

Until further notice

Requirements

2- 4 years of hands-on laboratory experience
Strong experience in: Protein purification
Protein expression
Molecular biology
Tissue culture
Must be authorized to work in the United States
Bachelor’s or Master’s degree in: Biochemistry
Molecular Biology
Cellular Biology
Immunology

Job Responsibility

Purify antibodies and recombinant proteins using AKTA FPLC and manual methods
Follow SOPs, GMP practices, and ISO 13485 standards with accurate documentation
Perform analytical testing using SEC, SDS-PAGE, Western blot, MADLS, and qPCR
Conduct protein expression and transfection using mammalian cell lines (CHO, hybridomas) and E. coli
Execute experiments using advanced molecular biology techniques
Perform and analyze multi-color Flow Cytometry experiments
Analyze data using FlowJo and FCS Express
Independently interpret results, troubleshoot issues, and plan follow-up experiments
Collaborate with cross-functional teams to meet timelines
Support lab operations, scheduling, and equipment maintenance

Fulltime

Biology Scientist 2

We are looking for a highly motivated Scientist II to support research and devel...

Location

United States , San Diego

Salary:

Not provided

MillenniumSoft Inc

Expiration Date

Until further notice

Requirements

2- 4 years of hands-on laboratory experience
Strong experience in: Protein purification
Protein expression
Molecular biology
Tissue culture
Protein purification using liquid chromatography
Protein expression (mammalian, bacterial, insect systems)
Aseptic technique and cell culture
Flow Cytometry data acquisition and analysis
Molecular biology techniques

Job Responsibility

Purify antibodies and recombinant proteins using AKTA FPLC and manual methods
Follow SOPs, GMP practices, and ISO 13485 standards with accurate documentation
Perform analytical testing using SEC, SDS-PAGE, Western blot, MADLS, and qPCR
Conduct protein expression and transfection using mammalian cell lines (CHO, hybridomas) and E. coli
Execute experiments using advanced molecular biology techniques
Perform and analyze multi-color Flow Cytometry experiments
Analyze data using FlowJo and FCS Express
Independently interpret results, troubleshoot issues, and plan follow-up experiments
Collaborate with cross-functional teams to meet timelines
Support lab operations, scheduling, and equipment maintenance

Fulltime

Scientist, Biology

We are seeking a highly motivated and organized Scientist II to contribute to th...

Location

United States , San Diego

Salary:

Not provided

MillenniumSoft Inc

Expiration Date

Until further notice

Requirements

Minimum of 2-5 years of laboratory experience required
Extensive hands-on experience with flow cytometry
Proficiency in tissue culture techniques, including transfection of cells for protein expression
Understanding of biochemistry and molecular biology
Hands-on experience designing, performing, and analyzing flow cytometry experiments, preferably on BD flow cytometers (LSRII, LSR Fortessa, Canto, Aria)
Proficient in tissue culture techniques
Familiarity with molecular biology (DNA preparation)
Software proficiency: BD FACSDiva, FlowJo, FCS Express, and Microsoft Office Suite
Effective interpersonal skills and ability to work in a cross-functional team-oriented environment
Strong written and oral communication skills

Job Responsibility

Execute experiments with varying complexity using multi-color Flow Cytometry
Analyze data using FCS Express and FlowJo software
report test results, including completion of all required documentation and database entries as required by protocols and SOPs
Responsible for transfection and expression of antibodies and recombinant proteins in cell lines, hybridoma tissue culture, and culture of various cell lines for testing
Day-to-day problem solving and cross-functional team-based activities to ensure that daily operations and timelines are met
Independently analyze research data, solve problems with minimal guidance, and effectively plan follow-up experiments
Involvement with scheduling, operational, and maintenance duties required within the laboratory

Fulltime

Scientist - Molecular And Cell Biologist

We are seeking a molecular and cell biologist to join our team as a temporary as...

Location

United States , Research Triangle Park

Salary:

40.00 - 44.00 USD / Hour

MillenniumSoft Inc

Expiration Date

Until further notice

Requirements

B.A./B.S. in Chemistry, Biology, Biochemistry, Microbiology, Biotechnology, or related field
2+ year experience in cell/molecular biology laboratory environment (university or industry)
Prior experience in BSL2 environment required
Demonstrated expertise in cell culture
DNA isolation and QC required
Excellent attention to detail with an understanding of laboratory practices required
Learning agility and timely execution of tasks required

Job Responsibility

Adherence to all laboratory SOPs, including BSL2 procedures
Accurate and comprehensive documentation in LIMS/QA systems (GLP environment)
Mammalian cell culture
DNA and protein purification and characterization
Set-up and analysis of bisulfite conversion experiments
Set-up and analysis of qPCR assays
Handling of human clinical samples

Fulltime

Select Country

Scientist, Molecular Biology

Job Responsibility

Requirements

Nice to have

What we offer

Looking for more opportunities?