Scientist, Cellular Immunology Preclinical

• Conduct hands-on laboratory experiments following established protocols to generate CAR T cells
• Perform and optimize cytotoxicity and flow cytometry assays
• Perform and validate ELISpot, ELISA, Luminex, or other assays as needed
• Maintain and expand, bank, and manage various cell lines
• Actively contribute to process improvements and the implementation of new technologies
• Perform lab associated tasks in accordance with Cabaletta Bio lab safety policies and SOPs
• Ensure proper maintenance and cleanliness of laboratory equipment and workspaces
• Maintain accurate and well-organized records and electronic laboratory notebook
• Analyze experimental data using basic statistical methods and software tools to generate meaningful insights
• Work collaboratively within a multidisciplinary team, actively participating in team meetings and discussions
• Communicate experimental results and findings effectively to colleagues and supervisors through written reports and oral presentations

• Ph.D. in Immunology, Cell Biology, Molecular Biology, or a related field with 0-2 years, or Master's degree with a minimum of 5 years, or Bachelor’s degree with minimum of 10 years of experience
• Hands-on experience with cell culture and basic molecular biology techniques
• General lab skills, including aseptic techniques and human tissue handling required
• Must have prior experience and be highly skilled at mammalian cell culture (aseptic techniques)
• Experience in primary cell husbandry, cytotoxicity assays, and flow cytometry
• Must be highly organized and able to work independently
• A high level of flexibility to support various other activities and the ability to learn new techniques outside of existing field of expertise
• Strong team orientation and passion for continuous self-development
• Strong organizational skills, attention to detail, and the ability to follow protocols accurately
• Effective written and verbal communication skills to share experimental findings and collaborate with team members

• Experience working in a research or industry setting related to immunology, cell therapy, or gene editing
• Experience in industry or in a startup industrial setting
• Solid understanding of CAR T cell therapy, immune cell biology, and cellular immunotherapy
• Enthusiasm for learning and contributing to innovative research in the field of CAR T cell therapy

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