Scientist: Antibody Investigation Job at Proclinical (Tarrytown)

Scientist II, Cell Line Engineering

BigHat is looking for an energetic and motivated individual to lead cell line en...

Location

United States , San Mateo

Salary:

145000.00 - 165000.00 USD / Year

BigHat Biosciences

Expiration Date

Until further notice

Requirements

PhD in biology-related discipline with minimum of 3+ years industry experience, preferably in an environment utilizing cell lines for antibody discovery and engineering
In depth molecular biology knowledge for plasmid construction and experience selecting expression vectors and promoter types
Experience culturing various cell types, including adherent, suspension, shaker flask etc. High level of organization in handling multiple cell lines simultaneously for manipulation and maintenance
Demonstrated hands-on success in using CRISPR/Cas9, transposon, or lentivirus based technologies
Adept with Fluorescence or magnetic-bead based cell sorting methods, and clonal selection and maintenance
Prior use of automation for cell culture a plus

Job Responsibility

Onboard all the core components necessary for engineering cell lines for expressing pipeline targets including expression vectors, gene delivery methods, selective antibiotic concentration determination protocols, expression validation and cell sorting capabilities
Culture and maintain a variety of cell types
generate diverse target cell lines including knock-outs, stable cell lines overexpressing one or more targets, and reporter cell lines
Perform the validation of cell line expression using flow and sequencing (Sanger or NGS) based methods
Generate bulk pool and single cell populations utilizing FACS to select for cell lines of various expression levels
Maintain an organized cell line inventory with all relevant documentation
Investigate target expression biology to recapitulate the most native conditions for expression
Work with end user stakeholders to confirm correct domain expression and associated sequences
In collaboration with end user stakeholders, establish the workflows, timelines and deliverables for cell line engineering from request to hand-off
Collaborate with automation engineers to automate routine cell culture workflows to increase efficiencies and throughput

What we offer

Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
Dental, and vision coverage through Guardian
Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
401(k) with company match
DTO, two weeks of company-wide shutdown, and 12 company holidays
Paid parental leave

Fulltime

Process Development Senior Scientist - Drug Product Technologies

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part...

Location

United States , Thousand Oaks

Salary:

126066.05 - 170559.95 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]
OR Master’s degree and 3 years of Scientific experience
OR Bachelor’s degree and 5 years of Scientific experience

Job Responsibility

Work effectively in a fast-paced, matrixed environment, collaborating across process development, research, regulatory, and manufacturing teams to advance programs and communicate technical recommendations to both scientific peers and leadership
Plan and execute formulation and fill/finish process studies for early-stage programs
Develop and characterize liquid and lyophilized formulations for biologics, with particular emphasis on ADC drug product formulation, handling, and lab-scale sterile filling
Build process understanding across unit operations to support scalable drug product development
Evaluate in-use compatibility and drug product stability under clinical conditions
Investigate ADC- and biologics-relevant CQAs (e.g., aggregation, fragmentation, drug-to-antibody ratio, free payload, charge/size variants, subvisible particles, surface interactions) to inform formulation and process design decisions
Leverage high-throughput tools for formulation screening and processability assessments
Identify and address technology gaps impacting ADC stability, linker-payload integrity, protein-excipient interactions, and process-related stress responses
Apply machine learning, AI, and data science to predictive modeling, workflow acceleration, and decision-making
Ensure development approaches are phase-appropriate, from discovery through clinical manufacturing

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible

Fulltime

R&D Formulation Scientist

The Formulation Scientist under the direction of Process Development Director is...

Location

Spain , Leon

Salary:

Not provided

PCI Pharma Services

Expiration Date

Until further notice

Requirements

Master’s degree in pharmaceutics or a related scientific discipline
At least 5 years’ experience in formulation development of product formulations in solution, suspension, emulsion and lyophilized forms for small molecules and biological products, defining QTPPs and CQAs, selecting suitable form of API and designing characterization studies, compatibility, solubility, dissolution, physico-chemical stability, etc.
Good level of spoken English and Spanish
Very good written communication skills

Job Responsibility

Development of product formulations in solution, suspension, emulsion and lyophilized forms for small molecules and biological products (mAb: monoclonal antibodies
ADC: antibody drug conjugate
proteins, peptides, oligonucleotides and high potency products)
Define and update the QTPPs and CQAs of the formulation: efficacy, safety, stability, purity and potency, etc.
In partnership with the client aid in the selection of suitable form of API for final drug product through pre-formulation and formulation techniques e.g. polymorph, isomeric conformation, melting point, hygroscopicity, pH and logP, particle size
Evaluation and selection of excipients according to QTTP. Selection and concentration of the formulation excipients and definition of the CMA of the selected excipients
Design of tests to evaluate the behavior of excipients and APIs: characterization studies, compatibility, solubility, dissolution, physico-chemical stability, etc.
Application of DoE methodology to design, perform and analyze laboratory scale experiments for the optimization of formulations and their manufacturing processes
Selection, design and execution of supporting studies and documentation for the development of the project: general studies such as characterization, compatibility, robustness, stability, etc. and specific biological products studies such as freeze-thaw, shear stress, protein content, silicone compatibility, etc.
Selection of appropriate equipment, manufacturers and technologies for technical and manufacturing transfer. Perform tasks related to pre-clinical batches, including toxicological studies

What we offer

Competitive salary
Health insurance + reimbursement for medication
English classes
Discounts on various activities
Partnerships with gyms
Referral programme

Fulltime

Principal Scientist

This role bridges clinical expertise in transfusion medicine with product innova...

Location

United States , Norcross, Georgia

Salary:

Not provided

werfen

Expiration Date

Until further notice

Requirements

Bachelor’s or Master’s degree in Medical Laboratory Science, Immunohematology, or related field
ASCP SBB (Specialist in Blood Banking) certification required
Minimum of 5 years of experience in a transfusion service or blood center
industry experience preferred
Strong understanding of methodologies for blood group serology, molecular typing (PCR and NGS), antibody identification, and transfusion protocols
Experience with diagnostic product development, clinical trials, or innovation projects
Excellent communication, organizational, and problem-solving skills
Familiarity with IVD product lifecycle and regulatory pathways
Experience with blood bank automation
Strong communication and cross-functional collaboration skills

Job Responsibility

Serve as the internal expert on transfusion practices, immunohematology, and blood bank workflows
Provide clinical input into the design and development of new diagnostic assays, products, instruments, and software tools
Translate customer needs and regulatory requirements into product design inputs and specifications
Collaborate with R&D, engineering, and marketing teams to evaluate and develop novel technologies (e.g., molecular typing, next gen serology based testing, AI-assisted interpretation, automation)
Participate in feasibility studies, usability testing, and clinical trials for new products
Analyze performance data and contribute to product performance testing and regulatory submissions
Support R&D teams as a consultant to help investigate technical challenges
Represent the company at scientific conferences, workshops, and customer meetings
Develop educational content to help build internal team competancies
Ensure all activities align with regulatory standards (FDA, CE-IVDR, ISO 13485) and industry best practices

Fulltime

Hgv Class 1 - Artic

JRL Plant & Logistics are looking for an experienced HGV Class 1 driver for a pe...

Location

United Kingdom , Biggleswade

Salary:

17.00 - 18.50 GBP / Hour

JRL Group

Expiration Date

Until further notice

Requirements

HGV Class 1 licence
Experience of driving in the UK
Full CPC and Digi-tacho card
Good understanding of driver's hours and working time
Ability to complete paperwork
Experience of delivering construction equipment / materials preferred

Job Responsibility

Driving HGV artic
Some nights out / tramping will be required
Must be able to follow current legislation EU drivers hours rules, Working time directive for mobile workers, Road Transport directive
Must be able to communicate in a courteous and helpful manner at all times
Must understand the various types of ticket and aggregate types

What we offer

performance related bonus after 3 months
£22.50 Nights Out
10 hour shifts
Full Uniform Provided
28 days holiday (Pro Rata)

Fulltime

Pharmacy Technician

At CVS Health, we are focused on transforming health care for our customers and ...

Location

United States , Hinckley

Salary:

17.00 USD / Hour

CVS Health

Expiration Date

August 10, 2026

Requirements

Must comply with any state board of pharmacy requirements or laws governing the practice of pharmacy, which includes but is not limited to, age, education, and licensure/certification
If the state board of pharmacy does not address or mandate a minimum age requirement, must be at least 16 years of age
If the state board of pharmacy does not address or mandate a minimum educational requirement, must have a high school diploma or equivalent, or be actively enrolled in high school or high school equivalency program
State-level licensure and national certification requirements vary by state
Regular and predictable attendance, including nights and weekends
Ability to complete required training within designated timeframe
Attention and Focus: Ability to concentrate on a task over a period of time
Ability to pivot quickly from one task to another
Ability to confirm prescription information and label accuracy
Customer Service and Team Orientation

Job Responsibility

Support the pharmacy team in delivering operational and service excellence
Assist patients and customers to deliver an exceptional experience
Ensure that pharmacy operations run smoothly, prescriptions are filled promptly, safely, and accurately
Provide caring service that exceeds patient expectations
Operate as part of the pharmacy team through consistent application of SOPs, best practices, and effective communication
Complete a rigorous company training program
Satisfy all registration, licensing, and certification requirements
Follow pharmacy workflow procedures at each workstation
Contribute to positive patient experiences by showing empathy and genuine care
Complete basic inventory activities

What we offer

Dental
Vision
Wellness resources
Employee discounts
Access to certain voluntary benefits
Other programs

Parttime

Automotive Detailer - Car Washer

Enterprise Mobility is seeking a responsible, dedicated person to join our team ...

Location

United States , Wake Forest

Salary:

14.50 USD / Hour

Enterprise Holdings

Expiration Date

Until further notice

Requirements

Must have a valid driver's license with no more than 2 moving violations and/or at-fault accidents on driving record in the past 3 years
No drug or alcohol related conviction on driving record in the past 5 years
Must be authorized to work in the United States and not require work authorization sponsorship by our company for this position now or in the future.
Must be at least 18 years old

Job Responsibility

Clean, sanitize, vacuum, and prepare vehicle interior according to industry-standard protocols
Wash, clean and dry the vehicle's exterior - this might include cars of different sizes, as well as vans and trucks.
Check fuel level and warning lights: inspect windshield for damage
factory reset/restore vehicle setting to clear prior customer data
check for customer items and place anything of value in Lost & Found
verify that registration is present, current and matches the license plate.
Check fluid levels and add as needed
check tire condition, pressure and tread depth
inspect vehicle exterior for damage
Fuel and stage vehicle

What we offer

Paid time off
Employee discount
401k retirement plan
Training and development

Parttime

Night Social Care Worker

We have set cookies to enhance your experience, but you have the option to disab...

Location

United Kingdom , Salisbury

Salary:

12.80 - 12.90 GBP / Hour

Choice Care Group

Expiration Date

July 16, 2026

Requirements

Being patient, reliable, flexible, a team player and a good communicator

Job Responsibility

Providing personal care including bathing, toileting, dressing and help with feeding
Medication administration
Assisting and getting involved in residents' daily activities, hobbies or outings
Following care plan guidance alongside Company policies and procedures
Developing an open, honest, and considerate working relationship with residents
Maintaining written daily records
Attending and completing training as required

What we offer

Learning Academy
Holiday entitlement starting from 28 days inclusive of Bank Holidays
Sick pay entitlement
Employee Assistance Programme
Refer a friend scheme
Choiceversary
Christmas bonus
Life insurance
Annual staff awards
Complex in-house training

Parttime

Select Country

Scientist: Antibody Investigation

Job Description

Job Responsibility

Requirements

Nice to have

Looking for more opportunities?