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10x Genomics Logo 10x Genomics · Research and Development

Scientist 2- Spatial Biology and Biophysics

United States, Pleasanton Employment contract 139700.00 - 188900.00 USD / Year · Job Posted June 28, 2026
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Job Description

We are looking for an exceptional, multidisciplinary scientist to drive new research and product development efforts in our Spatial Biology department. The ideal candidate will have a proven track-record in molecular biology and biophysics with extensive experience designing and working with biomolecule imaging platforms (including 10x Genomics Xenium). This position necessitates a deep understanding of molecular biology as you will be applying your skills and knowledge to optimize and evaluate new assays in the area of spatial transcriptomics. Additionally, this role will require you to interact closely with colleagues in several departments including computational biology, software, engineering and microfluidics. You should have a strong analytical background, be driven by developing revolutionary new products and technologies, and enjoy working in a fast-paced, innovative and truly multi-disciplinary environment.

Job Responsibility

  • Contribute molecular biology and biophysics expertise and leadership to cross-disciplinary product development teams to ensure project milestones and technological specifications are met
  • Design and execute experiments using novel imaging and biochemistry platforms integral to various spatial technology platforms under development at 10x Genomics. This includes in-depth analysis and reporting of your data through documentation and presentations to internal groups
  • Work closely with computational biologists and optical engineers to interpret data generated by novel optical and biochemical assays
  • Develop demonstrated and robust protocols that will be used internally across various teams during product development

Requirements

  • PhD in Molecular Biology, Biophysics, Physical Chemistry or related field
  • 3+ years of relevant experience in situ hybridization, imaging and spatial techniques, preferably in the Biotechnology industry
  • Proven ability to design novel molecular biology assay schemes, as evidenced by peer-reviewed publications or published patents
  • Strong analytical background
  • Strong organizational skills
  • Strong written and oral communication skills
  • Strong troubleshooting and problem solving skills
  • Ability to work in a fast-paced and quickly changing environment
  • Desire to build game-changing technologies and impact the world of life science research

Nice to have

  • Experience with the 10x Genomics Xenium platform is a plus
  • Fluency in R, Python or AI-aided coding to perform ad-hoc analysis is a plus
  • Skills in image analysis are a plus

What we offer

  • Equity grants
  • Comprehensive health and retirement benefit programs
  • Annual bonus program or sales incentive program
  • Health Package
  • Easy-to-use Benefits
  • Family oriented
  • Generous Time Off
  • Award-Winning Workplace
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