CrawlJobs Logo

Scientist – Research Computational Biology

amgen.com Logo

Amgen

Location Icon

Location:
India , Hyderabad

Category Icon

Job Type Icon

Contract Type:
Not provided

Salary Icon

Salary:

Not provided

Job Description:

The ARIA Computational Biology team is seeking a talented and creative computational biologist to further our mission of serving patients by advancing and replenishing the Amgen therapeutic pipeline. In this role you will apply your expertise in data science and disease biology to accelerate the identification, prioritization, and validation of transformative therapeutic targets in a dynamic cross-functional research environment.

Job Responsibility:

  • Extracting biological insight from complex multi-modal omics and screening data to characterize disease endotypes and mechanisms, identify novel targets, and test therapeutic hypotheses
  • Developing and leveraging methods/platforms to (1) guide prioritization of targets across diverse diseases and therapeutic modalities and (2) deliver foundational target insights, including characterization of expression biodistribution and isoform complexity
  • Developing advanced capabilities for discovery of novel disease-enriched isoforms using long-read transcriptomics, proteomics, and screening technologies
  • Partnering with our data science and information systems teams to incorporate tools and analyses developed within ARIA Computational Biology into integrated R&D platforms

Requirements:

  • Ph.D. in computational biology, bioinformatics, data science, or a related discipline OR Master’s degree with 3+ years of relevant research experience
  • Strong programming skills (Python, R, Linux/Unix), familiarity with cloud computing environments, HPC, and collaborative coding practices (e.g., Git)
  • Track record of designing and executing holistic computational strategies to address challenging research questions
  • Proven expertise in the analysis and interpretation of single cell omics data
  • Excellent presentation and communication skills to convey complex findings to diverse audiences
  • Self-starter with a collaborative mindset and a drive for continuous growth

Nice to have:

  • Solid immunology background, including application to the interpretation of single-cell oncology and/or inflammatory disease data
  • Strong understanding of RNA and protein isoform complexity, including underlying biology and computational approaches for characterization using long-read transcriptomics
  • Experience leveraging and fine-tuning transcriptional foundation models and biomedical knowledge graphs to further research goals
  • Familiarity with public data resources (e.g. DepMap, Human Cell Atlas, TCGA, GTEx, and Tahoe-100M) frequently used to augment analyses of internally generated data
  • Experience developing and deploying tools and pipelines to endpoints such as interactive portals (e.g. RShiny apps), workflow management systems (e.g Nextflow), and agentic frameworks

Additional Information:

Job Posted:
December 18, 2025

Work Type:
On-site work
Job Link Share:

Looking for more opportunities? Search for other job offers that match your skills and interests.

Briefcase Icon

Similar Jobs for Scientist – Research Computational Biology

Senior Scientist – Research Computational Biology

Join Amgen’s Mission of Serving Patients. The ARIA Computational Biology team is...
Location
Location
United States
Salary
Salary:
143320.00 - 174539.00 USD / Year
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Doctorate in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable]
  • Master’s degree and 3 years of relevant research experience
  • Bachelor’s degree and 5 years of relevant research experience
  • Strong programming skills (Python, R, Linux/Unix), familiarity with cloud computing environments, HPC, and collaborative coding practices (e.g., Git)
  • Track record of designing and implementing creative and holistic computational strategies to address challenging research questions
  • Demonstrated expertise in the analysis and interpretation of single cell omics data
  • Excellent presentation and communication skills to convey complex findings to diverse audiences
  • Self-starter with a collaborative mentality and a drive for continuous growth
Job Responsibility
Job Responsibility
  • Extracting biological insight from complex multi-modal omics and screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses
  • Developing and leveraging methods/platforms to discover, prioritize, and validate targets across diverse diseases and therapeutic modalities
  • Innovative research in close partnership with Amgen therapeutic area scientists, spanning both internal pipeline programs and external partnerships
  • Partnering with our data science and information systems teams to incorporate tools and analyses developed within ARIA Computational Biology into integrated R&D platforms
What we offer
What we offer
  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models, including remote and hybrid work arrangements, where possible
  • Fulltime
Read More
Arrow Right

Scientist, Biological Sciences

An exciting opportunity is available to join Altos Labs. We are seeking highly m...
Location
Location
United States , San Diego
Salary
Salary:
116450.00 - 247000.00 USD / Year
altoslabs.com Logo
Altos Labs
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD and a documented record of professional achievement in the form of impactful publications
  • Excellent computer skills, including advanced proficiency with Google apps, Excel, and Powerpoint graphic skills to produce documents and manage office projects
  • Excellent professional writing skills and the ability to attune through writing and presentations to a variety of audiences including senior executives through entry-level employees
  • Problem-solving skills sufficient to identify issues, conduct research, and develop innovative solutions
  • Ability to maintain cooperative working relationships with a broad range of people, including staff colleagues, lab members, faculty, outside agencies and collaborators, and the community
  • Demonstrated high productivity and ability to complete work in a timely manner
  • Ability to organize work and set priorities
  • Ability to focus on details to produce accurate, quality work driven by deadlines
  • Ability to work in a dynamic environment and with others in a team
  • Strengths in dealing with ambiguity
Job Responsibility
Job Responsibility
  • Engage in ground-breaking and innovative science
  • Support and manage internal/external collaborations in one or more multidisciplinary projects to accelerate essential research activities
  • Study the mechanistic basis of cell programming for health and rejuvenation
  • Responsible for mentoring graduate students
  • Responsible for developing project-specific experimental strategies, techniques, and procedures
  • Responsible for helping PI train lab members, including scientists and technicians
  • Contribute to writing and dissemination of research results
  • Carry out research projects in collaboration with the PI
Read More
Arrow Right

Computational Biologist

Are you a data-driven scientist passionate about turning complex biological data...
Location
Location
Canada , Toronto
Salary
Salary:
Not provided
amaris.com Logo
Amaris Consulting
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD or Master’s degree in Computational Biology, Bioinformatics, Genomics, or a related field
  • Proven experience applying computational biology methods in a pharmaceutical or biotech setting
  • Proficiency in programming languages such as Python, R, or Perl
  • Experience with high-throughput data analysis and visualization tools
  • Solid understanding of molecular biology and biological systems
  • Strong communication skills and ability to work collaboratively across scientific teams
Job Responsibility
Job Responsibility
  • Analyze large-scale biological and multi-omics datasets (genomics, transcriptomics, proteomics, etc.)
  • Develop and apply computational models, pipelines, and algorithms to support drug discovery and development
  • Collaborate with cross-functional teams including bioinformaticians, data scientists, and wet lab researchers
  • Interpret results and present findings to scientific and non-scientific stakeholders
  • Contribute to the design of experiments and data collection strategies
  • Ensure data quality, reproducibility, and compliance with scientific and regulatory standards
What we offer
What we offer
  • An international community bringing together more than 110 different nationalities
  • An environment where trust is central: 70% of our leaders started their careers at the entry level
  • A strong training system with our internal Academy and more than 250 modules available
  • A dynamic work environment that frequently comes together for internal events (afterworks, team buildings, etc.)
  • Fulltime
Read More
Arrow Right

Associate Vice President for Research Computing

The Associate Vice President (AVP) for Research Computing serves as the senior e...
Location
Location
United States of America , Rochester
Salary
Salary:
205245.00 - 328392.00 USD / Year
urmc.rochester.edu Logo
University of Rochester
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s degree in a relevant field of study.
  • Doctoral or advanced degree in a relevant field of study, advanced strongly preferred.
  • Minimum of 10 years of experience in informatics and computational research, with at least 5 years in a leadership role preferred.
  • Experience as a faculty member in higher education preferred.
  • Experience working in research-intensive higher education environment preferred.
  • Deep understanding of the research lifecycle and advanced knowledge of HPC architectures, scientific software, cloud-based research environments, and large-scale data storage.
  • Working knowledge of scientific concepts in fields such as biology, biochemistry, genomic, imaging, chemistry, physics and data science / AI
  • Proven ability to lead large technical teams, foster faculty partnerships, and manage multimillion-dollar research computing portfolios.
  • Strong communication skills and ability to interact effectively at all organization levels.
  • Broad IT experience including solutions architecture, application development, engineering, business analysis, and project management.
Job Responsibility
Job Responsibility
  • Lead the development and execution of a long-range strategic plan for research computing that supports the university’s R1 research mission, including investments in HPC, research storage, AI/ML environments, cloud platforms, secure data enclaves and staffing.
  • Collaborate with the Vice President for Research and IT, Deans, and faculty leaders to define institutional priorities, align resources, and support cutting-edge, interdisciplinary research initiatives.
  • Represent the University in national and international consortia focused on research computing infrastructure, research data governance, and secure research computing.
  • Serve as a strategic advisor to executive leadership on research policy, funding, and risk management related to advanced research computing.
  • Oversee Operations, performance, and lifecycle management of the University’s research computing environment, including HPC clusters and cloud platforms.
  • Lead cross-functional technical teams responsible for system design, user support, research application integration, and compliance with research security standards (e.g.NIST 800-171, FISMA)
  • Oversee service-level agreements, uptime metrics, downtime and maintenance procedures and communications and annual investment planning to ensure the environment remains resilient, scalable, and aligned with faculty needs.
  • Act as a campus-wide leader and trusted advisor to faculty and research teams across disciplines, proactively identifying research needs and aligning computational services accordingly.
  • Lead outreach, onboarding, and education programs that expand awareness of research computing services and improve access and usability for all research teams, especially those in emerging or underserved disciplines.
  • Oversee consultation and proposal development services that support grant applications, including effort related to compute budgeting, data management planning, and infrastructure letters of support.
  • Fulltime
Read More
Arrow Right

Research Scientist

As an AI Research Scientist, you will conduct groundbreaking research on computa...
Location
Location
United States , San Francisco
Salary
Salary:
Not provided
chaidiscovery.com Logo
Chai Discovery
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Ph.D. or equivalent research experience in Machine Learning, Computational Biology, Bioinformatics, Computational Chemistry, or a related field
  • Strong publication or project record in top ML or life-science venues (NeurIPS, ICML, Nature Methods, PLoS CB, J. Chem. Inf. Model., etc.)
  • Proficient in Python and deep-learning frameworks
  • Experience training and evaluating large models on protein, antibody, or small-molecule data, or demonstrably transferable ML expertise
  • Able to translate open-ended scientific questions into tractable modeling experiments
  • Skilled at wrangling large biological or chemical datasets, computing meaningful metrics, and visualizing results for diverse audiences
  • Enjoy working in cross-functional teams, aligning with wet-lab scientists, software engineers, and product leads
  • Clear communicator who can distill complex findings into next-step recommendations for both technical and non-technical stakeholders
  • Curious, ambitious, and comfortable iterating quickly on v0 ideas
  • Motivated by turning breakthrough research into real-world therapeutic impact
Job Responsibility
Job Responsibility
  • Conduct groundbreaking research on computational modeling for biological applications
  • Push the frontier of AI drug design
What we offer
What we offer
  • Frontier technology: work on the technologies that promises to fundamentally change how new therapeutics are created
  • World-class people: work with world-renowned leaders in the AI x Biology ecosystem
  • Velocity and ownership: we move incredibly fast and liberally distribute ownership, which means continuous learning and career growth opportunities are guaranteed
  • Strong culture and mission: we foster a supportive culture that is mission-driven and high-energy
  • Highly competitive compensation: we attract the best talent and compensate them accordingly
  • Fulltime
Read More
Arrow Right

Staff Bioinformatics Scientist - Genetics

The Staff Bioinformatics Scientist is largely self-driven, working in collaborat...
Location
Location
United States , San Diego
Salary
Salary:
160000.00 - 240000.00 USD / Year
exactsciences.com Logo
Exact Sciences
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Ph.D. in bioinformatics, computational biology, computer science, mathematics, or related field
  • or Master’s degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 4 years of experience in lieu of a Ph.D.
  • or Bachelor’s degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 6 years of experience in lieu of Ph.D.
  • 8+ years of industry or academia experience in bioinformatics
  • 6+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry
  • Demonstrated experience in developing statistical and quantitative methods
  • Deep knowledge and thorough understanding of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics
  • Demonstrated expertise in product/assay research, design, or development
  • Basic computer skills to include Internet navigation, Email usage, and word processing
  • Proficient in Microsoft Office to include Excel, Word, and PowerPoint
Job Responsibility
Job Responsibility
  • Conduct comprehensive analyses within several product or technology areas and identify problems and discrepancies
  • Independently plan and develop algorithms
  • Independently develop, plan, and analyze results of experiments within several product or technology areas within defined timelines
  • effectively present and clearly communicate findings at data meetings, group meetings and project team meetings to inform and enable project progression
  • Critically analyze research/experimental data, interpret the results, and provide insights into the next steps and the direction of the project for successful outcomes
  • Contribute towards the development of timeline and plan for new assignments/study/projects
  • Provide technical guidance to junior scientists in project teams
  • Manage bench-generated data and bioinformatics outputs within high performance computing (HPC) or cloud computing environment
  • Determine, utilize, and apply methods or technologies effectively and provide ideas for new techniques, when appropriate
  • Maintain knowledge of technological industry developments that could assist in completion of an assignment or aid in the development of new processes or procedures
What we offer
What we offer
  • paid time off (including days for vacation, holidays, volunteering, and personal time)
  • paid leave for parents and caregivers
  • a retirement savings plan
  • wellness support
  • health benefits including medical, prescription drug, dental, and vision coverage
  • bonus eligible
  • Fulltime
Read More
Arrow Right

Senior / Principal Machine Learning Scientist

Our mission is to restore cell health and resilience through cell rejuvenation t...
Location
Location
United Kingdom , Cambridge
Salary
Salary:
136000.00 - 261050.00 GBP / Year
altoslabs.com Logo
Altos Labs
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Ph.D. in Machine Learning, Computer Science, Artificial Intelligence, Statistics, or a related quantitative field
  • 6+ years of relevant post-PhD work experience in either an academic or industry setting
  • Proven experience developing and applying complex machine learning models
  • A strong track record of leading and publishing innovative, peer-reviewed research in top-tier ML conferences or high-impact scientific journals
  • Excellent scientific communication skills
  • Expertise in several of the following: deep learning, reinforcement learning, generative models, language models, computer vision, Bayesian inference, causal reasoning & inference, transfer & multi-task learning, graph neural networks, active learning, hybrid mechanistic/ML models
  • Proven experience applying sophisticated ML techniques to molecular and cell biological data sets
Job Responsibility
Job Responsibility
  • Pioneer novel machine learning methodologies and statistical frameworks
  • Contribute to setting the long-term technical vision and research strategy for a core domain within the Institute of Computation
  • Translate your deep understanding of the mathematical and theoretical underpinnings of cutting-edge AI research into high-impact applications
  • Design, implement, and optimize large-scale machine learning systems using modern frameworks and agile practices
  • Develop and manage efficient distributed training strategies across multiple GPUs and compute clusters
  • Develop robust approaches for multi-modal data integration and cross-domain mapping to extract actionable biological insights
  • Apply computational thinking to solve problems in drug target identification, compound assessment, and prediction of cellular perturbation responses
  • Lead the full ML development lifecycle from theoretical conception and data strategy through model development, training, and evaluation
  • Act as a key technical mentor to Machine Learning Scientists and Engineers
  • Fulltime
Read More
Arrow Right

Senior Bioinformatics Scientist

Job Advert: Senior Bioinformatics Scientist. Our client is an emerging leader wi...
Location
Location
United States , San Francisco
Salary
Salary:
170000.00 - 190000.00 USD / Year
signifytechnology.com Logo
Signify Technology
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD in Biological Sciences, Bioinformatics, Computational Biology, or related field, with 3+ years of experience developing production-level bioinformatics pipelines
  • Deep expertise in analyzing bulk/single-cell RNAseq data and performing differential gene expression using state-of-the-art tools
  • Significant experience building production-level Snakemake (or Nextflow) pipelines, with local and cloud-based deployments
  • Strong knowledge of sequence analysis (alignment, assembly) and molecular biology, with experience in Oxford Nanopore and Illumina sequencing
  • Proficiency in Python (numpy, pandas, Jupyter, Biopython) and package management (e.g., Conda)
  • Hands-on experience with Docker, Apptainer, or Singularity for containerized workflows
  • Expertise in Git/GitHub and Linux shell scripting for version control and automation
  • Proficiency in developing intuitive web tools for bioinformatics reporting (e.g., R Shiny, Streamlit)
  • Familiarity with public genomic data repositories (e.g., NCBI, Ensembl) and large-scale genomic data processing
  • Strong communication skills and ability to write clean, maintainable, production-ready code
Job Responsibility
Job Responsibility
  • Designing and optimizing high-performance bioinformatics pipelines for processing thousands of daily samples, leveraging tools like Snakemake and cloud deployments
  • Innovating sequence analysis workflows for bulk/single-cell RNAseq, differential gene expression, and large-scale genomics, ensuring robust and scalable solutions
  • Troubleshooting complex sequencing data challenges, from biological artifacts to platform-specific issues, to ensure reliable outputs
  • Developing intuitive web tools (e.g., Streamlit, R Shiny) and data visualizations to transform raw bioinformatics data into actionable insights
  • Providing thought leadership and mentoring junior team members, fostering a culture of innovation and collaboration
  • Staying ahead of industry trends, integrating emerging bioinformatics tools to enhance our offerings for biopharma and research clients
What we offer
What we offer
  • Competitive Compensation: Highly competitive remuneration
  • Generous Time Off: 4 weeks paid time off + 10 paid holidays
  • Comprehensive Health Coverage: Health, dental, and vision insurance, plus life insurance and mental health coverage
  • Retirement and Wellness: 401(k) with matching, Health Advocate services, and gym membership
  • Impactful Work: Contribute directly to accelerating biotech research, supporting novel therapies and sustainability
  • Innovative Environment: Work with cutting-edge tools (e.g., Snakemake, Streamlit, AWS) and collaborate with top-tier researchers
  • Supportive Culture: Join a passionate, inclusive team that values creativity, mentorship, and professional growth
  • Fulltime
Read More
Arrow Right