Scientist – Molecular Biology & Pharmacology

• Develop and optimize Primary cell-based assays to support HTS, hits validation, and lead optimization for novel therapeutic targets
• Develop and execute cell-based assays to assess the effects of small molecules on cellular pathways, receptor activity, and phenotypic outcomes
• Evaluate and implement new technologies to enhance screen capabilities and assay performance
• Stay current with scientific literature and industry trends related to assay technologies, novel drug modalities, and drug discovery
• Represent department in multi-disciplinary project teams to present research results and provide scientific and technical support
• Collaborate with internal cross-functional teams and external partners to enable project progression

• Doctorate degree
• OR Master’s degree and 2 years of Molecular Biology and Pharmacology experience
• OR Bachelor’s degree and 4 years of Molecular Biology and Pharmacology experience
• Expertise in quantitative pharmacology, Cytokine secretion and Phosphorylation assay
• Mastery in isolating various primary cells such as different types of T and B cells
• A deep and broad understanding of the development, validation & execution of a wide array of cell-based assays such as cytokine secretion, cell migration, etc.
• Demonstrated ability to develop and implement cellular assays for target validation, hit identification, and lead optimization, such as MesoScale Discovery, HiBIT, NanoBRET, and cell reporter assays
• Familiarity with Luminex Multiplex assay, and proficiency in Flow Cytometry
• Highly skilled in the development & implementation of robust, automated, 384 or 1536-well plate-based assays using a wide range of detection methods (e.g., spectrophotometry, radiometry, luminescence, fluorescence)
• Experience with microplate readers and automated liquid handling systems (e.g., PerkinElmer Envision, Labcyte Echo, Agilent Bravo, etc.)
• Experience with data analysis and visualization software platforms (e.g., Genedata Screener, Tibco Spotfire, GraphPad Prism, etc.)
• Excellent organizational, interpersonal and communication skills, along with the ability to work in a flexible team-oriented environment

PhD in Immunology, Pharmacology, Cell Biology, Molecular Biology or a related field, with relevant postdoctoral experience preferred

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans