Research Technician

Dana-Farber Cancer Institute is seeking a highly motivated Research Technician to join its Structural Biology Core Facility. This position offers an opportunity to gain hands-on experience in structural biology and protein biochemistry while supporting a wide range of academic and translational research projects. The technician will perform recombinant protein expression and purification in bacterial and mammalian systems, and conduct in vitro biophysical and biochemical assays such as ITC and TSA to evaluate screening hits, inhibitors, chemical probes, and emerging compounds. Additional responsibilities may include protein crystallization and determination of high-resolution structures using X-ray diffraction. The individual will work closely with scientists in the core facility and collaborate with investigators in the Chemical Biology Program. Core staff are frequently included as co-authors on publications, and many go on to pursue graduate or medical school or careers in biotechnology. The positions in this job family will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.