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Research Technician – Cell Biology

United Kingdom, Cambridge · Job Posted January 25, 2026
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Job Description

We currently have an exciting opportunity for a Research Technician to join our service, providing technical support in the Joint AstraZeneca-Cancer Research Horizons Functional Genomics Centre (FGC), a unique and equal collaboration between industry and academia, with the goal to identify novel targets and resistance mechanism to create novel cancer medicines. To achieve this, the FGC is developing and applying advanced CRISPR/Cas technologies to perform genome-wide screens to interrogate gene function in the context of drug treatment to fully support AZ’s pre-clinical Oncology portfolio. The jobholder will mainly support the Functional Genomics team in performing routine genome-wide CRISPR screens and provide general support within both cell culture and molecular biology laboratories. The successful candidate will join Avantor on a 12-month contract and report to the Research Services Team Lead and will be task managed on a day-to-day basis within the client environment. This role is lab-based focusing on the delivery of the FGC’s technical support in accordance with Health and Safety and GLS requirements. The successful candidate will significantly contribute to the practical delivery of genome-wide CRISPR screens with hands-on experience of general mammalian tissue culture, with molecular biology techniques including Next Generation Sequencing libraries preparation being advantageous. Additional knowledge and experience in experimental set ups would also be valuable.

Job Responsibility

  • To carry out all scientific support activities mainly in the cell culture laboratories in accordance with Health and Safety guidelines and local agreements including the regulations governing COSHH, biological agents and genetically modified organisms as detailed in relevant AZ risk assessments
  • To be an effective member of the Functional Genomics team supporting project teams to meet their objectives
  • Supporting general day-to-day laboratory activities within cell culture labs as required and directed by the lead lab representative
  • Preparing and aliquoting cell culture reagents and maintaining stock levels
  • General housekeeping including organising and participating in lab cleaning rotas
  • To take a key role supporting tissue culture activities: Sterile culture of mammalian cells
  • Measuring growth kinetics of mammalian cells
  • Performing antibiotics kill curves
  • Generation and testing of Lentiviruses
  • Generation of Cas9 cell lines
  • Performing genome-wide CRISPR screens
  • To execute experimental procedures according to study plan and contribute to the interpretation of experimental data and planning of further experiments
  • To ensure accurate recording of results and methodologies in accordance with guidelines and effectively communicate to other members of the team, project, section and department
  • Accurate and prompt writing up of experiments into client’s electronic lab notebook

Requirements

  • Educated to bachelor’s degree level or similar with at least 6 months laboratory experience in a relevant scientific discipline
  • Practical experience of Mammalian cell culture
  • Proven ability to work collaboratively
  • Ability to work on own initiative and unsupervised to deadlines, planning, organising and setting priorities for own work showing well-developed organisational and time management skills
  • Outstanding communication skills on all levels, problem solving capabilities and ability to work as a team member
  • Ability to deal promptly, effectively and courteously with requests for information and to use initiative in solving problems and responding to queries ensuring compliance with standard procedures and practices
  • Computer literate: articulate, confident and competent in the use of Microsoft Word and Excel with experience of using databases, analytical packages and presenting data using standard techniques e.g. PowerPoint, spreadsheets, computerised reports etc.
  • Able to adapt emerging best practices and industry innovations
  • Ability to support a project manager and deliver to agreed deadlines

Nice to have

  • Additional knowledge and experience in experimental set ups would also be valuable
  • Molecular biology techniques including Next Generation Sequencing libraries preparation being advantageous

What we offer

  • Competitive salary and benefits package
  • Flexible approach to work in line with your qualifications and experience
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