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Work independently with only occasional suggestions to modify, vary or adapt standard laboratory procedures to perform research related activities to meet the specialized needs of the research projects of the Principal Investigator. Primary responsibilities are described below. Evening and weekend work will occasionally be required based upon experimental schedules and laboratory needs. Handling and use of laboratory animals, infectious agents, and chemicals will be required. Training in the safe handling of these agents is required, and will be provided. Exercise independent judgment and perform research activities independently with limited guidance from the principal investigator on adapting standard laboratory procedures to meet specific research-based goals. Ability to apply common sense approach to laboratory work, excellent time management, integration into an existing team, excellent interpersonal and communication skills are essential. It is anticipated that the role will be able to coordinate several projects simultaneously as well as train new laboratory members, including students, postdoctoral fellows and other technicians, on laboratory SOPs.
Job Responsibility:
Serve as Research Specialist I for a Principal Investigator in the Department of Environmental Medicine
Conduct and oversee processing and analysis of collected specimens for immunohistological, biochemical, and molecular techniques including microscopy analysis, immunohistochemistry, histological analysis, Western blotting, ELISA, neurotransmitter quantification, and other techniques
Train other laboratory members on these techniques
Oversee the tissue processing for mass spectrometry
Develop and optimize new laboratory techniques including writing laboratory SOPs and training other technical staff and students on such SOPs
Perform scientific literature searches and utilize such literature to develop SOPs and advise the principal investigator
Independently supervise and oversee large colonies of rodent breeding and maintenance
Oversee set up and conduct rodent inhalation exposures
Plan and oversee non-survival specimen collections from rodents
Supervise and train other members of the laboratory
Assist Principal Investigator and Senior Laboratory Staff with Planning and coordinating experimental timelines
Assist in manuscript preparation
Strict adherence to written SOPs is required
as is detailed, daily record keeping
Participate and contribute to regularly-scheduled laboratory meetings
Requirements:
Bachelor’s Degree required
1 year of related work experience involving direct assistance to researchers or equivalent combination of education and experience required
Operational understanding of basic laboratory equipment, including the ability to make solutions, use centrifuges, and accurately operate micropipettes required
Mathematical skills including basic algebra and the ability to use scientific notation required
Familiarity with Microsoft Office programs (Word, PowerPoint, Excel) required
Ability to generate and organize large sets of data, strains, and plasmids, and familiarity with all aspects of a laboratory to effectively help organize the lab required
Ability to troubleshoot and repair equipment as needed required
Excellent organizational skills to help coordinate a number of projects, skills to help train inexperienced personnel, ability to use common sense, and attention to detail required
Must be able to work some evenings and weekends to conduct experiments required
Nice to have:
Experiential knowledge of the basic workings of a research laboratory and common equipment including general knowledge of chemistry and biology
prior experience in inhalational exposures, handling research animals, rodent behavioral techniques, histology, ELISA, HPLC, and Western Blots