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Research Scientist

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IRBM

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Location:
Italy , Pomezia

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Contract Type:
Not provided

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Salary:

Not provided

Job Description:

The peptide chemistry unit is seeking a talented peptide chemist with a strong background in peptide & macrocycle chemistry, as well as expertise in organic synthesis. The successful candidate will be passionate about conducting high-quality scientific research to advance internal and external peptide drug discovery programs. The candidate will be involved in the design of new molecules to progress structure-activity relationship studies and in the planning and execution of multi-step syntheses, purification, and analytical characterization of complex peptides to achieve agreed-upon objectives in a timely manner. The successful candidate will communicate effectively with internal and external collaborators and will work efficiently in a multi-disciplinary team environment.

Job Responsibility:

  • Develop and execute synthetic strategies towards complex molecules using state-of-the-art synthetic methodologies
  • Analyze and identify compounds using different purification and spectroscopic techniques
  • Contribute to the design of peptides with improved potency and physiochemical properties to advance programs according to scientific strategies and goals within a project team setting
  • Present data and reports on project status at internal and external meetings
  • Conduct laboratory operations in a safe manner
  • Exhibit safety awareness and safe work practices
  • comply with all safety requirements according to Italian laws

Requirements:

  • Master of Science Degree (Laurea Magistrale) in Chemistry with 5 years of experience doing peptide chemistry in a pharmaceutical or biotech environment
  • PhD in Chemistry with one or more relevant postdoctoral experiences or with experience in a pharmaceutical or biotech environment
  • In/depth knowledge of peptide chemistry
  • Expertise in design and synthesis of complex peptides, including peptide conjugates, macrocycles, and small proteins
  • Mastery of use of laboratory equipment with a preference for knowledge on the use of peptide synthesizers
  • Design and execution of synthetic routes for the synthesis of amino acids and building blocks
  • Excellent knowledge of common purification techniques (HPLC, IEX, GPC) and analytical techniques (UPLC/HPLC and mass spectrometry)
  • Knowledge in structure elucidations of organic molecules by NMR and MS
  • Outstanding organizational skills
  • Excellent communication skills, both verbal and written
  • Good knowledge of English is mandatory
  • Ability to productively work in teams

Nice to have:

Experience in the discovery of therapeutic peptides in an industrial environment will be considered a plus

Additional Information:

Job Posted:
December 09, 2025

Employment Type:
Fulltime
Work Type:
On-site work
Job Link Share:

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