Research Scientist, Cell and Molecular Biology Job at Proclinical (Wilmington)

Scientist – Molecular Biology & Pharmacology

Join Amgen’s Mission of Serving Patients. In this vital role you will be respons...

Location

United States , South San Francisco

Salary:

131874.00 - 160907.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree
OR Master’s degree and 2 years of Molecular Biology and Pharmacology experience
OR Bachelor’s degree and 4 years of Molecular Biology and Pharmacology experience
Expertise in quantitative pharmacology, Cytokine secretion and Phosphorylation assay
Mastery in isolating various primary cells such as different types of T and B cells
A deep and broad understanding of the development, validation & execution of a wide array of cell-based assays such as cytokine secretion, cell migration, etc.
Demonstrated ability to develop and implement cellular assays for target validation, hit identification, and lead optimization, such as MesoScale Discovery, HiBIT, NanoBRET, and cell reporter assays
Familiarity with Luminex Multiplex assay, and proficiency in Flow Cytometry
Highly skilled in the development & implementation of robust, automated, 384 or 1536-well plate-based assays using a wide range of detection methods (e.g., spectrophotometry, radiometry, luminescence, fluorescence)
Experience with microplate readers and automated liquid handling systems (e.g., PerkinElmer Envision, Labcyte Echo, Agilent Bravo, etc.)

Job Responsibility

Develop and optimize Primary cell-based assays to support HTS, hits validation, and lead optimization for novel therapeutic targets
Develop and execute cell-based assays to assess the effects of small molecules on cellular pathways, receptor activity, and phenotypic outcomes
Evaluate and implement new technologies to enhance screen capabilities and assay performance
Stay current with scientific literature and industry trends related to assay technologies, novel drug modalities, and drug discovery
Represent department in multi-disciplinary project teams to present research results and provide scientific and technical support
Collaborate with internal cross-functional teams and external partners to enable project progression

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans

Fulltime

Senior Scientist – Research Computational Biology Platforms

The ARIA Computational Biology team is seeking a talented and creative computati...

Location

United States , South San Francisco; Boston; Thousand Oaks

Salary:

146404.00 - 198076.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

PhD in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable]
Master’s degree in computational biology, bioinformatics, data science, or a related discipline and 3 years of relevant research experience
Bachelor’s degree in computational biology, bioinformatics, data science, or a related discipline and 5 years of relevant research experience
Strong programming expertise in Python and R, with proficiency in Linux/Unix environments, cloud computing, HPC, and collaborative development practices (e.g., Git)
Experience developing complex computational tools and visualizations that translate biological insights into actionable strategies
Experience developing and deploying computational tools and pipelines, including use of workflow management systems (e.g., Nextflow), CI/CD practices, and interactive visualization tools (e.g., Shiny/Streamlit)
Strong background in molecular and systems biology
Demonstrated expertise in the analysis and interpretation of single-cell omics data
Experience leveraging and fine-tuning transcriptional foundation models, large language models (LLMs), and biomedical knowledge graphs to advance research objectives
Familiarity with high-value public data resources (e.g., DepMap, Human Cell Atlas, TCGA, GTEx, and Tahoe-100M) used to complement and enhance analyses of internal datasets

Job Responsibility

Developing and applying methods and platforms to discover, prioritize, and validate targets across a broad range of diseases and therapeutic modalities
Designing and building a Precision Targeting Engine that integrates internal and high-value public data into an automated, scalable framework with custom expression analytics across diverse data types and disease areas
Contributing to the design and evolution of Amgen’s preclinical omics data ecosystem in partnership with the Research Informatics team
Evaluating and integrating emerging AI/ML technologies (e.g., biological foundation models), and developing custom research agents to accelerate early pipeline efforts
Partnering with data science and information systems teams to embed tools and analyses developed within ARIA Computational Biology into integrated R&D platforms
Training and mentoring other scientists in the use of advanced research tools and platforms

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible

Fulltime

Stem Cell Scientist – Neural Research

This is a hands-on bench position ideal for a Scientist who enjoys experimental ...

Location

United States , Long Island City

Salary:

90000.00 - 120000.00 USD / Year

Strategic Employment Partners

Expiration Date

Until further notice

Requirements

PhD in stem cell biology, neuroscience, developmental biology, bioengineering, or related field
Hands-on experience with human iPSC culture and neuronal differentiation
Experience with cell characterization methods (e.g., ICC, qPCR, or similar)

Job Responsibility

Culture and differentiate human iPSCs into neuronal lineages
Design and optimize differentiation protocols
Develop neural culture systems
Characterize cells using molecular and cellular assays
Troubleshoot experiments and iterate as needed

What we offer

Health benefits
Equity opportunity
Flexible PTO
Opportunity to contribute to early-stage research in regenerative neuroscience within a mission-driven startup

Fulltime

Research Scientist Gcm - Oral Medicine Translational Research Laboratories

The Research Scientist is responsible for conducting basic and clinical translat...

Location

United States , Charlotte

Salary:

47.50 - 71.25 USD / Hour

Advocate Aurora Health

Expiration Date

Until further notice

Requirements

MD and/or Ph.D. with at least 3 years of relevant post-doctoral research in biochemistry, molecular biology, cell biology, or relevant biomedical fields preferred
Published in respected journals with high report factors preferred
Experience in biostatistics, bioinformatics, basic and translational research in oral Medicine preferred

Job Responsibility

Performs searches in bioreository, genomic and bioinformatic databases, analyzes data, and prepares presentations
Provides instruction and mentors to residents, post-doctoral fellows, students and research associates on the fundamentals of Oral Medicine Research, evidence-based medicine, research principles, and methodologies
Develops and Performs basic science and clinical translational research projects related, but not limited, to oral medicine, cancer, and autoimmune diseases
Collaborates on projects on the basic and clinical and translational aspects of oral medicine
Generates data quality check, data reports and analysis and writes progress reports
Writes manuscripts for publication in peer-reviewed journals
Prepares abstracts and presents research findings at local and national meetings
Conceives, develops, writes, and submits grant funding
Participates in safety and quality assurance activities

What we offer

Paid Time Off programs
Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability
Flexible Spending Accounts for eligible health care and dependent care expenses
Family benefits such as adoption assistance and paid parental leave
Defined contribution retirement plans with employer match and other financial wellness programs
Educational Assistance Program

Fulltime

Research Scientist GCM - Oral Medicine Translational Research Laboratories

The Research Scientist is responsible for conducting basic and clinical translat...

Location

United States , Charlotte

Salary:

47.50 - 71.25 USD / Hour

Advocate Health Care

Expiration Date

Until further notice

Requirements

MD and/or Ph.D. with at least 3 years of relevant post-doctoral research in biochemistry, molecular biology, cell biology, or relevant biomedical fields preferred
Published in respected journals with high report factors preferred
Experience in biostatistics, bioinformatics, basic and translational research in oral Medicine preferred

Job Responsibility

Performs searches in biorepository, genomic and bioinformatic databases, analyzes data, and prepares presentations
Provides instruction and mentors to residents, post-doctoral fellows, students and research associates on the fundamentals of Oral Medicine Research, evidence-based medicine, research principles, and methodologies
Develops and Performs basic science and clinical translational research projects related, but not limited, to oral medicine, cancer, and autoimmune diseases
Collaborates on projects on the basic and clinical and translational aspects of oral medicine
Generates data quality check, data reports and analysis and writes progress reports
Writes manuscripts for publication in peer-reviewed journals
Prepares abstracts and presents research findings at local and national meetings
Conceives, develops, writes, and submits grant funding
Participates in safety and quality assurance activities

What we offer

Paid Time Off programs
Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability
Flexible Spending Accounts for eligible health care and dependent care expenses
Family benefits such as adoption assistance and paid parental leave
Defined contribution retirement plans with employer match and other financial wellness programs
Educational Assistance Program
Premium pay such as shift, on call, and more based on a teammate's job
Incentive pay for select positions
Opportunity for annual increases based on performance

Fulltime