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Research Scientist, Cell and Molecular Biology

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Proclinical

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Location:
United States , Wilmington

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Contract Type:
Not provided

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Salary:

Not provided

Job Description:

Research Scientist specializing in Cell and Molecular Biology to contribute to cancer drug discovery programs. Focus on developing pre-clinical model systems to identify and validate novel therapeutic targets.

Job Responsibility:

  • Design, execute, and interpret experiments using chemical and genetic approaches with scientific independence
  • Develop and utilize disease-relevant preclinical models to explore target biology and address complex hypotheses
  • Support small- and large-molecule screening efforts, ensuring data quality and translational relevance
  • Collaborate with internal teams across drug discovery functions to achieve shared objectives
  • Adapt and acquire new skills and competencies as required by project needs
  • Communicate complex scientific findings effectively to both internal and external audiences

Requirements:

  • Degree in molecular biology, stem cell biology, or a related field (Bachelor's with relevant experience or Master's with industry experience)
  • Proven expertise in developing and optimizing functional cellular assays for proliferation, differentiation, and apoptosis in biologically relevant models
  • Strong theoretical and practical knowledge of primary stem cells
  • experience in hematopoietic stem cell biology or myeloid malignancies (e.g., MPN, MDS, AML) is highly preferred
  • Proficiency in molecular and cellular biology techniques such as ELISA, MSD-based assays, Western blotting, multicolor flow cytometry, and CRISPR-Cas9 gene-editing platforms

Nice to have:

Experience with CRISPR-based screening is a plus

Additional Information:

Job Posted:
January 15, 2026

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