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Research Scientist - Directed Evolution of Nitrogenases

https://www.csiro.au/ Logo

CSIRO

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Location:
Australia, Canberra

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Category:
Research and Development

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Contract Type:
Not provided

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Salary:

114000.00 - 123000.00 AUD / Year
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Job Description:

We have a dynamic and inclusive team within the Engineering Nitrogenase into Plants team within CSIRO’s Agriculture and Food research unit. We are seeking applicants for the role of Research Scientist – Directed Evolution in Nitrogenases. If you take pride in your interpersonal skills and your ability to apply expertise in directed evolution in microbes for multi-gene pathways, we would love to hear from you. As the Research Scientist, your major aims will be to simplify the genetic complexity of native nitrogenases and also to improve the tolerance of nitrogenases to oxygen. Your wider team within CSIRO spans synthetic biology in plants and the biochemistry of metalloenzymes and your role will be to provide improved variants of nitrogenases that can be validated in plant-based assays.

Job Responsibility:

  • Design of synthetic DNA libraries for nitrogenases
  • Assembly of nitrogenase pathways for expression in microbes
  • Design of phenotyping assays that assess nitrogenase dependent growth
  • Development of molecular strategies for directed evolution
  • Methods for the rapid identification of the molecular basis of improved nitrogenase dependent growth
  • Managing a small team for improved rates of discovery
  • Other duties as directed

Requirements:

  • A PhD (or an equivalent combination of qualifications and research experience) in a relevant field such as directed evolution of microbes
  • Demonstrated experience with enzymes that use gases as a substrate
  • Demonstrated ability to perform high throughput screens for improved growth and the characterisation of the variants at a molecular level
  • Experience with managing small teams
  • Demonstrated ability to undertake original, creative and innovative research by generating and pursuing novel ideas and solutions to scientific research problems
  • A demonstrated publication history of authorship on scientific papers in peer reviewed journals and/or reports, grant applications or inventorship on patent applications

Nice to have:

  • Experience and general knowledge with plant synthetic biology
  • Experience with expression of pathways within plant organelles, such as mitochondria or plastids
What we offer:
  • 15.4% super
  • Flexible working arrangements
  • Leave entitlements
  • Career development opportunities

Additional Information:

Job Posted:
May 12, 2025

Expiration:
May 23, 2025

Employment Type:
Fulltime
Work Type:
On-site work
Job Link Share:
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