Research Lead, Chemical & Biological Risk

• Lead the full-stack mitigation strategy and implement solutions for biological and chemical misuse—from prevention to enforcement
• Ensure safeguards integrate seamlessly across OpenAI products and scale with usage
• Make decisive calls on technical trade-offs within the bio risk domain
• Partner with risk modeling leadership to align mitigation design with anticipated risks and coverage
• Drive rigorous safeguard testing by stress-testing the mitigation stack against evolving threats and product surfaces

• Passion for AI safety and motivated to make cutting-edge AI models safer for real-world use
• Demonstrated experience in deep learning and transformer models
• Proficiency with frameworks such as PyTorch or TensorFlow
• Strong foundation in data structures, algorithms, and software engineering principles
• Familiarity with methods for training and fine-tuning large language models, including distillation, supervised fine-tuning, and policy optimization
• Excel at working collaboratively with cross-functional teams across research, policy, product, and engineering
• Decisive leadership in high-stakes, ambiguous environments
• Significant experience designing and deploying technical safeguards at scale

Background knowledge in biosecurity, computational biology, or adjacent technical fields

• Medical, dental, and vision insurance for you and your family, with employer contributions to Health Savings Accounts
• Pre-tax accounts for Health FSA, Dependent Care FSA, and commuter expenses (parking and transit)
• 401(k) retirement plan with employer match
• Paid parental leave (up to 24 weeks for birth parents and 20 weeks for non-birthing parents), plus paid medical and caregiver leave (up to 8 weeks)
• Paid time off: flexible PTO for exempt employees and up to 15 days annually for non-exempt employees
• 13+ paid company holidays, and multiple paid coordinated company office closures throughout the year for focus and recharge, plus paid sick or safe time (1 hour per 30 hours worked, or more, as required by applicable state or local law)
• Mental health and wellness support
• Employer-paid basic life and disability coverage
• Annual learning and development stipend to fuel your professional growth
• Daily meals in our offices, and meal delivery credits as eligible
• Relocation support for eligible employees
• Additional taxable fringe benefits, such as charitable donation matching and wellness stipends