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Research Associate in Genome Stability and Proton Radiation

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The University of Manchester

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Location:
United Kingdom , Manchester

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Contract Type:
Not provided

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Salary:

37694.00 - 46049.00 GBP / Year

Job Description:

We are seeking a highly motivated Research Associate to join an exciting, funded project investigating the effects of proton and photon radiation on tissues from individuals with inherited chromosomal instability and telomere spectrum disorders, including Fanconi Anaemia and Bloom Syndrome. You will be embedded within the Genome Stability Laboratory and the PRECISE Proton Research Group, gaining hands-on experience with advanced proton radiation and DNA damage response facilities. Your work will involve tissue culture, wet-lab techniques and sophisticated data analysis to achieve the project’s ambitious objectives. You will contribute to the development of innovative experimental approaches using patient-derived tissues and study tumour cell responses in models with varying genomic instability - research with direct implications for cancer treatment and patient outcomes. The role offers the chance to collaborate with a multidisciplinary team of leading academic and clinical researchers, present findings at conferences and contribute to high-impact publications.

Job Responsibility:

  • Investigate the effects of proton and photon radiation on tissues from individuals with inherited chromosomal instability and telomere spectrum disorders
  • Gain hands-on experience with advanced proton radiation and DNA damage response facilities
  • Perform tissue culture, wet-lab techniques and sophisticated data analysis
  • Contribute to the development of innovative experimental approaches using patient-derived tissues
  • Study tumour cell responses in models with varying genomic instability
  • Collaborate with a multidisciplinary team
  • Present findings at conferences
  • Contribute to high-impact publications

Requirements:

  • PhD in a relevant discipline (or close to obtaining)
  • Experience in cell biology or genome stability research
  • Ability to work independently and as part of a multidisciplinary team

Nice to have:

Experience in radiation biology or DNA damage and repair

What we offer:
  • Fantastic market leading Pension scheme
  • Excellent employee health and wellbeing services including an Employee Assistance Programme
  • Exceptional starting annual leave entitlement, plus bank holidays
  • Additional paid closure over the Christmas period
  • Local and national discounts at a range of major retailers

Additional Information:

Job Posted:
February 17, 2026

Expiration:
February 23, 2026

Employment Type:
Fulltime
Work Type:
Hybrid work
Job Link Share:

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