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Research Associate In Bioengineering

United Kingdom, Manchester 37694.00 - 46049.00 GBP / Year · Job Posted July 04, 2026
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Job Responsibility

  • Perform physicochemical, histological, mechanical, and structural characterisation of decellularised tissue membranes and hybrid constructs supplied by industrial partner
  • Conduct biological validation across dermal and tendon repair models, including fibroblast, keratinocyte, tenocyte, and tendon-derived cell viability, proliferation, attachment, and migration assessments
  • Execute in vitro wound healing assays including scratch assay and transwell migration studies to evaluate wound closure kinetics and re-epithelialisation potential
  • Assess tenogenic differentiation including gene expression profiling of tendon-specific markers and collagen fibril alignment analysis
  • Perform ECM proteomic profiling and pro-tenogenic secretome analysis across construct systems

Requirements

  • PhD (or near completion) in biomaterials, biomedical engineering, tissue engineering, materials science, or a closely related discipline
  • Hands-on experience in mammalian cell culture, including primary cells or established cell lines relevant to dermal or musculoskeletal biology
  • Demonstrated experience in biomaterials characterisation including mechanical testing, rheology, and spectroscopic methods
  • Practical experience with histological techniques (e.g. H&E, Masson's trichrome, immunostaining)
  • Experience with cell viability assays, proliferation assays, and migration assays (scratch assay, transwell)

Nice to have

  • Experience with decellularisation techniques or characterisation of extracellular matrix scaffolds
  • Familiarity with ECM proteomic analysis, including sample preparation for mass spectrometry
  • Experience with tenogenic or dermal fibroblast differentiation models
  • Track record of peer-reviewed publications and/or conference presentations

What we offer

  • Generous employer contribution pension
  • 29 days annual leave plus bank holidays, along with Christmas closure
  • Ride to work and EV car scheme available

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