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This is where new knowledge is discovered. Baxter’s Research and Development teams work cross functionally to innovate, develop and introduce creative solutions for patients needs globally. From Scientists to Engineers, your work creates the products that save and sustain lives. This is where your work makes a difference. At Baxter, we believe every person—regardless of who they are or where they are from—deserves a chance to live a healthy life. It was our founding belief in 1931 and continues to be our guiding principle. We are redefining healthcare delivery to make a greater impact today, tomorrow, and beyond. Our Baxter colleagues are united by our Mission to Save and Sustain Lives. Together, our community is driven by a culture of courage, trust, and collaboration. Every individual is empowered to take ownership and make a meaningful impact. We strive for efficient and effective operations, and we hold each other accountable for delivering exceptional results. Here, you will find more than just a job—you will find purpose and pride.
Job Responsibility
To perform advanced characterization of complex injectable drugs, including iron formulations, proteins & peptides, oligonucleotides, carbohydrates & other biomolecular APIs and various impurities in lyophilized, liquid, emulsions & other formulations for regulatory submission following GLP norms
To manage outsourced studies at CROs, academic institutes & other external facilities, from study design, execution, analysis and report preparation. Traveling to external facilities, as and when required, is a mandatory requirement for this position
To demonstrate subject matter expertise and help overcome technical challenges in product development, by liaising with formulation and other cross-functional teams as a Subject Matter Expertise (SME)
To understand the project with guidance of Sub-department Manager and follow their instructions
To provide necessary assistance for various procurement activities, review quotations, engage suppliers to procure required goods & services in a timebound manner
To complete the planned work in the stipulated time frame, inform the Sub-department Manager if any deviation or issues are observed
To keep track of each activity related to product analysis and development activities
To carry out all the testing and data recording according to the approved SOPs/ ALCOA++ principle and current pharmacopoeia. Data recording in ELN and sign off must be completed on time
To verify the shelf life of the chemical or reagent before performing analysis of the material or product
To follow Good Documentation Practices & Good Laboratory Practices, maintain lab notebooks & other records appropriately
To investigate if any deviation / abnormalities are observed and report to Sub-department Manager
To check the trend of results before reporting the results
To keep the status of daily work and report to Sub-department Manager on daily basis
To undertake operation, calibration, preventive and breakdown mainte the instruments as per approved standard operating procedure. To report on the conclusion of preventive maintenance and breakdown maintenance to Sub-department Manager
To list all resources required for the study and keep track of routine requirements and ensure timely procurement of the same, verify the materials received for analysis from supplier as per given requirement
To complete training as per the quality matrix targets
To prepare and update the SOPs. To prepare method development and verification report
To perform the work as allocated by Sub-department Manager
To liaise with customers, staff and suppliers
To write / fill the record in legible writing
To keep the documentation online with analysis
To compile required data for Management Information System and provide to Sub-department Manager
In the absence of Officer, Sub-department Manager will ensure his roles and responsibilities
To communicate about any failure or abnormal notification or non-compliance in results to Sub- department Manager and help resolve them in a timely manner
To communicate project related issues to Sub-department Manager and follow the action plan
To keep status of daily work and report to Sub-department Manager on daily basis
Requirements
Masters (Pharmacy, or equivalent discipline) with 6 to 10 years of experience, or, PhD (biophysics, biochemistry or equivalent discipline) with 0 to 5 years of experience in SEC-UV-MALS and related methods encompassing liquid chromatography, light scattering, diffraction and light obscuration
Competency in the acquisition, processing and data analysis by SEC-UV-MALS and light scattering/diffraction/obscuration techniques for analysis of peptides and iron colloidal products for regulatory submissions is mandatory
Expertise in computational chemistry, molecular modeling and statistical methods are beneficial attributes
Basic understanding of working principles of biophysical & spectroscopic methods, like CD, FTIR, UV, EPR, Mossbauer, and fluorescence spectroscopy, particle XRD, microscopy methods (AFM & EM) & related orthogonal methods to assess structural properties of proteins and iron colloids
Proficiency in literature search through publication and patent databases, repositories (e.g. Pubmed), scientific webinars by regulatory agencies, etc, to remain updated on advanced characterization methods and recent scientific developments
Knowledge of pharmacopoeia, ICH Guidelines and means to implement them for product development
Experience in the operation, calibration and preventive maintenance of NMR and other instruments to ensure continued usage
Trouble shooting of various problems obtain during the product development
Knowledge of good laboratory practices and good documentation practices