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Lagator lab works at the intersection of evolutionary, molecular, micro and synthetic biology, to address questions about bacterial transcriptional regulation and antimicrobial resistance. We design synthetic genetic systems in bacteria to ask fundamental and applied questions about diverse topics: evolution of multidrug resistance; regulation of multi-drug efflux pumps; evolution of bacterial promoters and transcription factors; transcriptional crosstalk between plasmids and bacterial hosts. We use Escherichia coli as a model system.
Job Responsibility:
Work at the intersection of evolutionary, molecular, micro and synthetic biology, to address questions about bacterial transcriptional regulation and antimicrobial resistance
Design synthetic genetic systems in bacteria to ask fundamental and applied questions about diverse topics: evolution of multidrug resistance
regulation of multi-drug efflux pumps
evolution of bacterial promoters and transcription factors
transcriptional crosstalk between plasmids and bacterial hosts
Use Escherichia coli as a model system
Requirements:
Experience in molecular biology (molecular cloning on bacterial plasmids and chromosomes
Next-generation sequencing)
Experience in microbiology (sterile techniques
bacterial growth and fluorescence assays in plate reader and flow cytometer)
Experience in experimental evolution
Hold a qualification at QCF level 6 (such as a bachelor’s degree or equivalent) in a relevant biological science subject OR QCF level 2 passes (such as GCSE’s) in English and Mathematics and at least one Science subject and substantial relevant experience of working in a research laboratory
Nice to have:
Holding a higher education degree (MA or PhD)
What we offer:
Fantastic market leading Pension scheme
Excellent employee health and wellbeing services including an Employee Assistance Programme
Exceptional starting annual leave entitlement, plus bank holidays
Additional paid closure over the Christmas period
Local and national discounts at a range of major retailers