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Principal UI Engineer

United States, Boston · Job Posted May 05, 2026
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Job Description

Scientists around the world use Orion for early-stage drug discovery and design in the pursuit of improving human health. Orion combines the power of advanced HPC, computational methods, and in-browser 3D visualization & modeling to solve problems in drug discovery & design. Our innovative solutions enable customers to routinely model billions of compounds in-silico. Orion enables our customers to interactively explore chemical space, evaluate designs and gain scientific understanding. As a Principal UI Engineer, you will work with designers, scientists, and software engineers to enhance & extend Orion’s UI capabilities. You'll have the chance to work on a multitude of interesting challenges across scientific visualization, collaboration, data management, as well as new product & feature development. You’ll be part of a team building cutting edge features, as well as helping to modernize existing software.

Job Responsibility

  • Work with designers, scientists, and software engineers to enhance & extend Orion’s UI capabilities
  • Work on a multitude of interesting challenges across scientific visualization, collaboration, data management, as well as new product & feature development
  • Be part of a team building cutting edge features, as well as helping to modernize existing software

Requirements

  • BS in computer science/engineering, biology/chemistry or similar with a minimum of 7 years of experience OR MS with a minimum of 5 years of experience OR PhD with a minimum of 1 year of experience
  • Experience designing, developing, troubleshooting and debugging complex user interfaces and software systems as part of a team
  • Expert in JavaScript/Typescript/CSS/HTML
  • Experience with Vue 3, Pinia/VueX and application frameworks such as Nuxt.js
  • Experience with unit & end-to-end testing, CI/CD, source control, code review, comfortable using command line interfaces
  • Strong background of computer science fundamentals (data structures, algorithms)
  • Passionate to learn and explore new technologies and demonstrates good analysis and problem-solving skills
  • Ability to establish a close working relationship with peers in development, science, design and customer success, often across time zones
  • Take initiative to solve unexpected challenges during development
  • Willing to expand their knowledge and skills in both technical and scientific areas
  • Push to raise the bar while always operating with integrity

Nice to have

Experience in Life Sciences, HPC, Python, AWS, Web Workers, WebAssembly, and WebGL are a plus

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