This list contains only the countries for which job offers have been published in the selected language (e.g., in the French version, only job offers written in French are displayed, and in the English version, only those in English).
We are seeking a highly experienced and technically driven Principal Systems Engineer to lead systems engineering for a closed-loop epilepsy therapy system, with primary emphasis on neural interface performance, end-to-end system integration, full-stack data flow, and optimization of seizure detection algorithms within a regulated (PMA) development framework. The system includes an active implantable medical device (AIMD), custom external instruments, clinician and patient applications, and a secure cloud platform. The ideal candidate is a systems engineer who is strongest at the intersection of neural signals + real world data + integrated system behavior who can reason from electrode physics to algorithm metrics to telemetry and cloud pipelines, and knows how to turn that into testable requirements and credible verification evidence. This position will report directly to the VP of Engineering, will have significant input into Adraxe strategy and planning, and will collaborate closely with all technical disciplines at Adraxe.
System Integration & Test Leadership (PMA-Grade Evidence)
Safety, Risk, and Performance Boundaries for Closed-Loop Operation
Verification, Validation, and Test Strategy
Cross-Functional Leadership and Mentorship
Requirements:
B.S. in Systems, Computer Science, Electrical Engineering, Biomedical Engineering, Mechanical Engineering, or related field
10+ years (or equivalent) experience in systems engineering for complex electromechanical and software-intensive products
medical device experience strongly preferred
Demonstrated experience developing implantable and/or active therapeutic devices (e.g., neuromodulation, cardiac rhythm management, or similar)
Experience with implantable sensing modalities and neural signals (e.g., iEEG/ECoG/SEEG or related), including artifact sources and long-term recording challenges
Strong command of requirements development, decomposition, and traceability
System architecture and interface definition (ICDs)
System integration and V&V planning and execution for distributed systems
Risk management and safety engineering in regulated contexts
Proven ability to lead through influence across multi-disciplinary teams and drive cross-functional execution
Strong written and verbal communication skills, including the ability to produce clear, inspection-ready technical documentation
Nice to have:
M.S. or Ph.D. in Electrical Engineering, Biomedical Engineering, or related field
Experience supporting PMA development (design controls, DHF evidence, traceability, and system V&V evidence packages)
Experience with seizure detection/classification and/or robust biosignal detection methods in real-world settings
Experience designing and validating end-to-end data pipelines for regulated products (time sync, provenance, auditability, retention, access control)
Strong background in system integration testing for distributed systems (embedded + apps + cloud), including SIL/HIL, simulation, and test automation
Working knowledge of cybersecurity engineering for connected medical systems (threat modeling, encryption, key management, vulnerability management)