Principal Researcher - Generative AI Job at Microsoft Corporation (Redmond)

Senior / Principal Machine Learning Scientist

Our mission is to restore cell health and resilience through cell rejuvenation t...

Location

United Kingdom , Cambridge

Salary:

136000.00 - 261050.00 GBP / Year

Altos Labs

Expiration Date

Until further notice

Requirements

Ph.D. in Machine Learning, Computer Science, Artificial Intelligence, Statistics, or a related quantitative field
6+ years of relevant post-PhD work experience in either an academic or industry setting
Proven experience developing and applying complex machine learning models
A strong track record of leading and publishing innovative, peer-reviewed research in top-tier ML conferences or high-impact scientific journals
Excellent scientific communication skills
Expertise in several of the following: deep learning, reinforcement learning, generative models, language models, computer vision, Bayesian inference, causal reasoning & inference, transfer & multi-task learning, graph neural networks, active learning, hybrid mechanistic/ML models
Proven experience applying sophisticated ML techniques to molecular and cell biological data sets

Job Responsibility

Pioneer novel machine learning methodologies and statistical frameworks
Contribute to setting the long-term technical vision and research strategy for a core domain within the Institute of Computation
Translate your deep understanding of the mathematical and theoretical underpinnings of cutting-edge AI research into high-impact applications
Design, implement, and optimize large-scale machine learning systems using modern frameworks and agile practices
Develop and manage efficient distributed training strategies across multiple GPUs and compute clusters
Develop robust approaches for multi-modal data integration and cross-domain mapping to extract actionable biological insights
Apply computational thinking to solve problems in drug target identification, compound assessment, and prediction of cellular perturbation responses
Lead the full ML development lifecycle from theoretical conception and data strategy through model development, training, and evaluation
Act as a key technical mentor to Machine Learning Scientists and Engineers

Fulltime

New

Principal Research Engineer - Generative AI - AI Frontiers

The AI Frontiers lab at Microsoft Research is charted with ambitious research go...

Location

United States , Redmond

Salary:

139900.00 - 274800.00 USD / Year

Microsoft Corporation

Expiration Date

Until further notice

Requirements

Bachelors in Computer Science or relevant field AND 6+ years related experience
OR Master's Degree in Computer Science or related field AND 4+ years related experience
OR Doctorate in Computer Science or related field AND 3+ years related experience
OR equivalent experience
1+ year(s) experience developing with Python and Pytorch/JAX
Familiarity with architecture and optimizations for large language models
Hands-on work in debugging and profiling Pytorch distributed code
Basic understanding of working of CUDA kernels
Familiarity with pre-training, mid-training and/or post-training pipelines for language and/or multimodal models
Foundational understanding of reinforcement learning and key challenges in the field

Job Responsibility

Design, develop, execute, and implement technology research projects in collaboration with other researchers, engineers, and product groups
Be a part of research breakthroughs in the field and play a crucial role in developing, improving, and exploring the capabilities of Large Language Models (LLMs), reasoning and agentic AI
Embody our culture and values

Fulltime

Principal Machine Learning Data Scientist, Gen AI

Xometry is seeking a Principal Data & ML Scientist to join our Generative AI tea...

Location

United States , Waltham

Salary:

164000.00 - 213000.00 USD / Year

Cherry Ventures

Expiration Date

Until further notice

Requirements

A bachelor’s degree is required, but an advanced degree (M.S. or PhD) in computer science, machine learning, AI, or a related field is highly preferred
7+ years of experience in data science and machine learning, focusing on generative models, LLMs, or computer vision
Expertise in large-scale language and vision models (e.g., Transformers, GPT, VLMs)
Experience with multimodal data processing (e.g., combining text, image, and 3D data)
Proficient in Python, including key libraries such as PyTorch, TensorFlow, pandas, and numpy
Strong background in probability, statistics, and optimization techniques relevant to generative modeling
Familiarity with cloud computing resources and tools for model training and deployment (e.g., AWS SageMaker)
Familiar with software engineering principles, including version control, reproducibility, and continuous integration

Job Responsibility

Provide technical leadership to the Generative AI team, setting technical direction, defining best practices, and ensuring the team follows industry standards in AI and ML development
Lead strategic planning and roadmap development for generative AI initiatives, identifying high-impact projects and aligning them with Xometry’s business objectives
Develop and deploy generative AI models and large language models (LLMs) for multimodal document processing, focusing on extracting structured data from technical drawings, purchasing orders, and other complex documents
Lead the exploration and development of innovative text and image-based data processing solutions, including training and fine-tuning generative and language models
Design and implement efficient workflows for data preparation, cleaning, and augmentation to support the training of generative AI models
Utilize cloud platforms (e.g., Amazon Web Services) for large-scale data processing, model training, and deployment
Collaborate with cross-functional teams, including engineering and business teams, to align generative AI solutions with business needs and drive impactful applications
Mentor and guide team members on advanced machine learning techniques, model architecture design, and problem-solving strategies to elevate the team’s technical capabilities
Continuously experiment and iterate on model performance, tuning architectures and parameters to improve accuracy and efficiency in a fast-paced, agile environment
Stay updated with the latest research in generative AI, deep learning, and multimodal data processing, incorporating best practices and advancements into model development

What we offer

401(k) match
medical, dental and vision insurance
life and disability insurance
generous paid time off including vacation, sick leave, floating and fixed holidays, maternity and bonding leave
EAP, other wellbeing resources

Fulltime

Principal Machine Learning Data Scientist, Gen AI

Xometry is seeking a Principal Data & ML Scientist to join our Generative AI tea...

Location

United States , Denver

Salary:

164000.00 - 213000.00 USD / Year

Cherry Ventures

Expiration Date

Until further notice

Requirements

A bachelor’s degree is required, but an advanced degree (M.S. or PhD) in computer science, machine learning, AI, or a related field is highly preferred
7+ years of experience in data science and machine learning, focusing on generative models, LLMs, or computer vision
Expertise in large-scale language and vision models (e.g., Transformers, GPT, VLMs)
Experience with multimodal data processing (e.g., combining text, image, and 3D data)
Proficient in Python, including key libraries such as PyTorch, TensorFlow, pandas, and numpy
Strong background in probability, statistics, and optimization techniques relevant to generative modeling
Familiarity with cloud computing resources and tools for model training and deployment (e.g., AWS SageMaker)
Familiar with software engineering principles, including version control, reproducibility, and continuous integration

Job Responsibility

Provide technical leadership to the Generative AI team, setting technical direction, defining best practices, and ensuring the team follows industry standards in AI and ML development
Lead strategic planning and roadmap development for generative AI initiatives, identifying high-impact projects and aligning them with Xometry’s business objectives
Develop and deploy generative AI models and large language models (LLMs) for multimodal document processing, focusing on extracting structured data from technical drawings, purchasing orders, and other complex documents
Lead the exploration and development of innovative text and image-based data processing solutions, including training and fine-tuning generative and language models
Design and implement efficient workflows for data preparation, cleaning, and augmentation to support the training of generative AI models
Utilize cloud platforms (e.g., Amazon Web Services) for large-scale data processing, model training, and deployment
Collaborate with cross-functional teams, including engineering and business teams, to align generative AI solutions with business needs and drive impactful applications
Mentor and guide team members on advanced machine learning techniques, model architecture design, and problem-solving strategies to elevate the team’s technical capabilities
Continuously experiment and iterate on model performance, tuning architectures and parameters to improve accuracy and efficiency in a fast-paced, agile environment
Stay updated with the latest research in generative AI, deep learning, and multimodal data processing, incorporating best practices and advancements into model development

What we offer

401(k) match
medical, dental and vision insurance
life and disability insurance
generous paid time off including vacation, sick leave, floating and fixed holidays, maternity and bonding leave
EAP, other wellbeing resources

Fulltime

Principal Machine Learning Data Scientist, Gen AI

Xometry is seeking a Principal Data & ML Scientist to join our Generative AI tea...

Location

United States , Los Angeles

Salary:

164000.00 - 213000.00 USD / Year

Cherry Ventures

Expiration Date

Until further notice

Requirements

A bachelor’s degree is required, but an advanced degree (M.S. or PhD) in computer science, machine learning, AI, or a related field is highly preferred
7+ years of experience in data science and machine learning, focusing on generative models, LLMs, or computer vision
Expertise in large-scale language and vision models (e.g., Transformers, GPT, VLMs)
Experience with multimodal data processing (e.g., combining text, image, and 3D data)
Proficient in Python, including key libraries such as PyTorch, TensorFlow, pandas, and numpy
Strong background in probability, statistics, and optimization techniques relevant to generative modeling
Familiarity with cloud computing resources and tools for model training and deployment (e.g., AWS SageMaker)
Familiar with software engineering principles, including version control, reproducibility, and continuous integration

Job Responsibility

Provide technical leadership to the Generative AI team, setting technical direction, defining best practices, and ensuring the team follows industry standards in AI and ML development
Lead strategic planning and roadmap development for generative AI initiatives, identifying high-impact projects and aligning them with Xometry’s business objectives
Develop and deploy generative AI models and large language models (LLMs) for multimodal document processing, focusing on extracting structured data from technical drawings, purchasing orders, and other complex documents
Lead the exploration and development of innovative text and image-based data processing solutions, including training and fine-tuning generative and language models
Design and implement efficient workflows for data preparation, cleaning, and augmentation to support the training of generative AI models
Utilize cloud platforms (e.g., Amazon Web Services) for large-scale data processing, model training, and deployment
Collaborate with cross-functional teams, including engineering and business teams, to align generative AI solutions with business needs and drive impactful applications
Mentor and guide team members on advanced machine learning techniques, model architecture design, and problem-solving strategies to elevate the team’s technical capabilities
Continuously experiment and iterate on model performance, tuning architectures and parameters to improve accuracy and efficiency in a fast-paced, agile environment
Stay updated with the latest research in generative AI, deep learning, and multimodal data processing, incorporating best practices and advancements into model development

What we offer

401(k) match
medical, dental and vision insurance
life and disability insurance
generous paid time off including vacation, sick leave, floating and fixed holidays, maternity and bonding leave
EAP, other wellbeing resources

Fulltime

Principal Machine Learning Data Scientist, Gen AI

Xometry is seeking a Principal Data & ML Scientist to join our Generative AI tea...

Location

United States , North Bethesda

Salary:

164000.00 - 213000.00 USD / Year

Cherry Ventures

Expiration Date

Until further notice

Requirements

A bachelor’s degree is required, but an advanced degree (M.S. or PhD) in computer science, machine learning, AI, or a related field is highly preferred
7+ years of experience in data science and machine learning, focusing on generative models, LLMs, or computer vision
Expertise in large-scale language and vision models (e.g., Transformers, GPT, VLMs)
Experience with multimodal data processing (e.g., combining text, image, and 3D data)
Proficient in Python, including key libraries such as PyTorch, TensorFlow, pandas, and numpy
Strong background in probability, statistics, and optimization techniques relevant to generative modeling
Familiarity with cloud computing resources and tools for model training and deployment (e.g., AWS SageMaker)
Familiar with software engineering principles, including version control, reproducibility, and continuous integration

Job Responsibility

Provide technical leadership to the Generative AI team, setting technical direction, defining best practices, and ensuring the team follows industry standards in AI and ML development
Lead strategic planning and roadmap development for generative AI initiatives, identifying high-impact projects and aligning them with Xometry’s business objectives
Develop and deploy generative AI models and large language models (LLMs) for multimodal document processing, focusing on extracting structured data from technical drawings, purchasing orders, and other complex documents
Lead the exploration and development of innovative text and image-based data processing solutions, including training and fine-tuning generative and language models
Design and implement efficient workflows for data preparation, cleaning, and augmentation to support the training of generative AI models
Utilize cloud platforms (e.g., Amazon Web Services) for large-scale data processing, model training, and deployment
Collaborate with cross-functional teams, including engineering and business teams, to align generative AI solutions with business needs and drive impactful applications
Mentor and guide team members on advanced machine learning techniques, model architecture design, and problem-solving strategies to elevate the team’s technical capabilities
Continuously experiment and iterate on model performance, tuning architectures and parameters to improve accuracy and efficiency in a fast-paced, agile environment
Stay updated with the latest research in generative AI, deep learning, and multimodal data processing, incorporating best practices and advancements into model development

What we offer

401(k) match
medical, dental and vision insurance
life and disability insurance
generous paid time off including vacation, sick leave, floating and fixed holidays, maternity and bonding leave
EAP, other wellbeing resources

Fulltime

Principal Machine Learning Data Scientist, Gen AI

Xometry is seeking a Principal Data & ML Scientist to join our Generative AI tea...

Location

United States , Lexington

Salary:

Not provided

Cherry Ventures

Expiration Date

Until further notice

Requirements

A bachelor’s degree is required, but an advanced degree (M.S. or PhD) in computer science, machine learning, AI, or a related field is highly preferred
7+ years of experience in data science and machine learning, focusing on generative models, LLMs, or computer vision
Expertise in large-scale language and vision models (e.g., Transformers, GPT, VLMs)
Experience with multimodal data processing (e.g., combining text, image, and 3D data)
Proficient in Python, including key libraries such as PyTorch, TensorFlow, pandas, and numpy
Strong background in probability, statistics, and optimization techniques relevant to generative modeling
Familiarity with cloud computing resources and tools for model training and deployment (e.g., AWS SageMaker)
Familiar with software engineering principles, including version control, reproducibility, and continuous integration

Job Responsibility

Provide technical leadership to the Generative AI team, setting technical direction, defining best practices, and ensuring the team follows industry standards in AI and ML development
Lead strategic planning and roadmap development for generative AI initiatives, identifying high-impact projects and aligning them with Xometry’s business objectives
Develop and deploy generative AI models and large language models (LLMs) for multimodal document processing, focusing on extracting structured data from technical drawings, purchasing orders, and other complex documents
Lead the exploration and development of innovative text and image-based data processing solutions, including training and fine-tuning generative and language models
Design and implement efficient workflows for data preparation, cleaning, and augmentation to support the training of generative AI models
Utilize cloud platforms (e.g., Amazon Web Services) for large-scale data processing, model training, and deployment
Collaborate with cross-functional teams, including engineering and business teams, to align generative AI solutions with business needs and drive impactful applications
Mentor and guide team members on advanced machine learning techniques, model architecture design, and problem-solving strategies to elevate the team’s technical capabilities
Continuously experiment and iterate on model performance, tuning architectures and parameters to improve accuracy and efficiency in a fast-paced, agile environment
Stay updated with the latest research in generative AI, deep learning, and multimodal data processing, incorporating best practices and advancements into model development

Principal AI/ML & Innovation Engineer

We are seeking Principal AI/ML & Innovation Engineer who will be leading initiat...

Location

Puerto Rico , Aguadilla

Salary:

Not provided

Hewlett Packard Enterprise

Expiration Date

Until further notice

Requirements

Bachelor's or master’s degree in computer science, engineering, data science, machine learning, artificial intelligence, or closely related quantitative discipline
Typically, 10-15 years’ experience
Solid understanding of fundamental AI and machine learning concepts, including supervised and unsupervised learning, deep learning, reinforcement learning, natural language processing, computer vision, and statistical modeling
Proficient in implementing and deploying various machine learning algorithms, such as decision trees, random forests, support vector machines, and neural networks
Knowledge of popular machine learning frameworks and libraries like TensorFlow, PyTorch, or sci-kit
Strong understanding of GitHub CoPilot, Cursor, N8N, vibe coding, Windsurf, and similar technologies
Experience in Cloud Infrastructure (AWS, Azure, etc)
Knowledge of Open Source, Linux, etc
Understanding of Devops, SRE
Expertise in deep learning techniques, architectures, and frameworks (e.g., convolutional neural networks (CNN), recurrent neural networks (RNN), generative adversarial networks (GAN), etc.)

Job Responsibility

Designing, developing, and deploying advanced machine learning models and algorithms
Leading research initiatives to explore novel approaches and technologies
Designing the architecture of AI systems and ensuring scalability, performance, and reliability
Collaborating with other teams, such as data scientists, software engineers, and product managers
Providing technical leadership and mentorship to junior engineers
Overseeing and guiding multiple design review sessions across different projects
Partnering with the engineering manager and team lead to establish long-term design and implementation strategies
Leading efforts to incorporate feedback loops and continuous improvement processes
Leading meetings, ensuring efficient progress tracking, issue resolution, and team coordination
Creating and delivering high-level presentations and reports to executive stakeholders

What we offer

Health & Wellbeing
Personal & Professional Development
Unconditional Inclusion

Fulltime

Principal Researcher - Generative AI

Microsoft Corporation

Location:
United States , Redmond ▼
New York City

Category:
Research and Development

Contract Type:
Not provided

Salary:

Job Description:

Job Responsibility:

Requirements:

Additional Information:

Job Posted:
March 25, 2026

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