Principal Researcher - Deep Learning Job at Microsoft Corporation (Redmond)

Principal Applied Researcher AI/NLP

At PointClickCare our mission is simple: to help providers deliver exceptional c...

Location

United States

Salary:

195800.00 - 217500.00 USD / Year

PointClickCare

Expiration Date

Until further notice

Requirements

PhD or comparable level of experience in Computer Science, Math, Physics, Engineering or a related field
4-10+ year industry experience building solutions in commercial SaaS, including at least 4 years working in applications of NLP, Search or AI/ML technologies for healthcare
Strong interest in applying AI/ML/NLP to healthcare related problems and data
Expert-level practical, hands-on experience developing and applying a wide range of techniques in Natural Language Processing, including fine tuning of LLMs and other Transformer models, plus one or more additional AI/ML or Search related areas of expertise to solve real-world problems at scale
Demonstrated ability to lead and perform research and experimentation to select appropriate approaches, algorithms, evaluation methods, and frameworks, as well as tasks such as feature selection, language modeling, evaluation and fine tuning or training models, applying standard approaches or developing new tools or workflows as needed to meet project requirements
Significant experience building and deploying AI/machine learning and NLP models for large-scale SaaS products, including familiarity with industry standard software development concepts such as scaling issues, version control, CI/CD pipelines, and security
Solid understanding and experience with transformer models and multiple kinds of NLP and ML models and approaches including logistic regression, random forest, ensemble methods, SVM, KNN, reinforcement learning, and other ML techniques
Proficiency in Python and Java required. Proficiency in JavaScript or TypeScript and modern UI frameworks for building prototype or tool front ends desired
Proficiency doing data engineering for ML and NLP applications, including exposure to database systems and proficiency with SQL
Proficiency building models from big data using modern packages, models and data analysis stacks such as NumPy, SciPy, Pandas, Scikit-learn, PyTorch, Keras, LightGBM, fastText, NLTK, and spaCy. Proficiency fine tuning Hugging Face Transformers required

Job Responsibility

You will be applying NLP including GenAI and other AI/ML techniques to develop model systems and solutions, collaborating across functions to scale and integrate advanced solutions into successful end user experiences in large-scale cloud based SaaS production environments for healthcare
You will be working with product leaders, clinical informaticists, data scientists, UI/UX researchers and designers, other AI and machine learning and domain experts, engineering teams and others, including work with customers and users who are healthcare professionals
Design, build and evaluate solutions that may involve structured or unstructured data including speech or natural language for healthcare use cases, delivering capabilities such as summarization, predictive models, recommenders, semantic search, extraction, classification or other NLP, AI or machine learning based techniques
You will be performing research and experimentation to select appropriate approaches, algorithms, evaluation methods and frameworks and doing the R&D to deliver model systems
You will perform, oversee and assist in data collection, data cleaning, data analysis, algorithm selection or design, prompt tuning, parameter fine tuning, training, development and evaluation of systems that deliver responsible AI solutions at scale, using existing or developing new tools or workflows as needed
As a principal applied researcher, you will bring deep technical expertise and also provide mentorship on advanced AI, NLP, data science, statistical and machine learning methods and technologies, helping the organization develop new capabilities for innovative solutions
You will have substantial independence and responsibility from day one

What we offer

Benefits starting from Day 1
Retirement Plan Matching
Flexible Paid Time Off
Wellness Support Programs and Resources
Parental & Caregiver Leaves
Fertility & Adoption Support
Continuous Development Support Program
Employee Assistance Program
Allyship and Inclusion Communities
Employee Recognition … and more

Fulltime

Senior / Principal Machine Learning Scientist

Our mission is to restore cell health and resilience through cell rejuvenation t...

Location

United States , Redwood City; San Diego

Salary:

260950.00 - 509450.00 USD / Year

Altos Labs

Expiration Date

Until further notice

Requirements

Ph.D. in Machine Learning, Computer Science, Artificial Intelligence, Statistics, or a related quantitative field
6+ years of relevant post-PhD work experience in either an academic or industry setting
Proven experience developing and applying complex machine learning models
A strong track record of leading and publishing innovative, peer-reviewed research in top-tier ML conferences or high-impact scientific journals
Excellent scientific communication skills
Expertise in several of the following: deep learning, reinforcement learning, generative models, language models, computer vision, Bayesian inference, causal reasoning & inference, transfer & multi-task learning, graph neural networks, active learning, hybrid mechanistic/ML models
Proven experience applying sophisticated ML techniques to molecular and cell biological data sets

Job Responsibility

Pioneer novel machine learning methodologies and statistical frameworks
Contribute to setting the long-term technical vision and research strategy for a core domain
Translate your deep understanding of the mathematical and theoretical underpinnings of cutting-edge AI research into high-impact applications
Design, implement, and optimize large-scale machine learning systems
Develop and manage efficient distributed training strategies across multiple GPUs and compute clusters
Develop robust approaches for multi-modal data integration and cross-domain mapping
Apply computational thinking to solve problems in drug target identification, compound assessment, and prediction of cellular perturbation responses
Lead the full ML development lifecycle
Act as a key technical mentor to Machine Learning Scientists and Engineers

Senior / Principal Machine Learning Scientist

Our mission is to restore cell health and resilience through cell rejuvenation t...

Location

United Kingdom , Cambridge

Salary:

136000.00 - 261050.00 GBP / Year

Altos Labs

Expiration Date

Until further notice

Requirements

Ph.D. in Machine Learning, Computer Science, Artificial Intelligence, Statistics, or a related quantitative field
6+ years of relevant post-PhD work experience in either an academic or industry setting
Proven experience developing and applying complex machine learning models
A strong track record of leading and publishing innovative, peer-reviewed research in top-tier ML conferences or high-impact scientific journals
Excellent scientific communication skills
Expertise in several of the following: deep learning, reinforcement learning, generative models, language models, computer vision, Bayesian inference, causal reasoning & inference, transfer & multi-task learning, graph neural networks, active learning, hybrid mechanistic/ML models
Proven experience applying sophisticated ML techniques to molecular and cell biological data sets

Job Responsibility

Pioneer novel machine learning methodologies and statistical frameworks
Contribute to setting the long-term technical vision and research strategy for a core domain within the Institute of Computation
Translate your deep understanding of the mathematical and theoretical underpinnings of cutting-edge AI research into high-impact applications
Design, implement, and optimize large-scale machine learning systems using modern frameworks and agile practices
Develop and manage efficient distributed training strategies across multiple GPUs and compute clusters
Develop robust approaches for multi-modal data integration and cross-domain mapping to extract actionable biological insights
Apply computational thinking to solve problems in drug target identification, compound assessment, and prediction of cellular perturbation responses
Lead the full ML development lifecycle from theoretical conception and data strategy through model development, training, and evaluation
Act as a key technical mentor to Machine Learning Scientists and Engineers

Fulltime

Principal Machine Learning Tech Lead

We are looking for a highly skilled and innovative Principal Machine Learning Te...

Location

United States

Salary:

312000.00 USD / Year

Blue River Technology

Expiration Date

Until further notice

Requirements

8-12 years of experience developing high-performance ML systems
Experience shaping the technical vision for larger projects and providing guidance while contributing to core capabilities
Strong leadership and communication skills, and demonstrated experience in leading and mentoring teams
Hands-on work experience with GPU-based computing on large data sets
Extensive experience with deep learning frameworks (e.g., PyTorch)
Bachelor’s or Master’s Degree in Computer Science or a related field, graduate degree preferred

Job Responsibility

Lead the design, development, and deployment of machine learning and computer vision models that power real-time perception for autonomous agricultural robots
Own the full ML lifecycle—from dataset design and data collection through training, evaluation, model optimization, and deployment on embedded platforms
Collaborate cross-functionally with robotics engineers, software developers, and hardware teams to integrate perception systems into field-ready machines
Lead a team of CVML engineers, fostering technical growth, strong engineering practices, and a culture of experimentation and delivery
Define and execute the ML roadmap, balancing research exploration with production needs to meet performance, safety, and robustness targets in challenging environments
Prototype and validate new approaches quickly, using both real-world and synthetic data to improve detection, segmentation, and scene understanding under variable conditions (lighting, occlusion, dust, etc)
Continuously evaluate model performance in the field and refine approaches to maximize reliability and generalization across crop types, terrains, and climates

What we offer

bonus and benefit programs
inclusive workplace
programs including recruiting, mentorship, career development, and learning & development
reasonable accommodation for individuals with disabilities

Fulltime

Senior Principal Machine Learning Engineer

You’ll form a new team of passionate engineers dedicated to building and scaling...

Location

United States

Salary:

222300.00 - 348975.00 USD / Year

Atlassian

Expiration Date

Until further notice

Requirements

Bachelor’s, Master’s, or PhD in Computer Science, Statistics, Mathematics, or a related field, or equivalent practical experience
12+ years of industry experience in machine learning, data science, or AI, with a proven track record of delivering production-grade ML systems
Deep expertise in Python, Go, or Java, with the ability to write performant, production-quality code
familiarity with SQL, Spark, and cloud data environments (e.g., AWS, GCP, Databricks)
Experience building and scaling ML models for business-critical applications, ideally in security, privacy, anti-abuse, or compliance domains
Strong communication skills, able to explain complex ML concepts to diverse audiences and influence stakeholders
Demonstrated ability to solve ambiguous, complex problems and drive projects from ideation to production
Agile development mindset, with a focus on iterative improvement and business impact

Job Responsibility

Lead AI/ML Strategy for Trust: Drive the development and implementation of advanced machine learning algorithms and AI systems for Trust, Security, Product Abuse, and Compliance use cases (e.g., threat detection, vulnerability management, privacy automation, AI safety)
Architect and Scale ML Platforms: Design and build scalable, secure, and reliable ML infrastructure and pipelines, ensuring compliance with privacy and regulatory requirements
AI Safety and Responsible AI: Develop and champion AI safety practices, including output moderation, explainability, and alignment with evolving regulatory frameworks
Cross-Functional Collaboration: Partner with product, engineering, security, privacy, and analytics teams to deliver transformative AI/ML solutions that enhance Atlassian’s trust posture
Mentorship and Leadership: Mentor and guide ML engineers and data scientists, fostering a culture of technical excellence, innovation, and continuous improvement
Innovation and Research: Stay at the forefront of AI/ML research, evaluating and applying the latest techniques (e.g., LLMs, anomaly detection, privacy-preserving ML) to real-world Trust challenges
Platform Enablement: Build reusable ML services and APIs that empower other teams to integrate AI/ML into their products and workflows
Operational Excellence: Ensure high availability, reliability, and security of all ML-powered Trust platforms and services

What we offer

health and wellbeing resources
paid volunteer days
benefits, bonuses, commissions, and equity

Fulltime

Senior Principal Machine Learning Engineer - LLM Post-Training and Optimization

Atlassian is seeking a highly skilled and experienced Senior Principle Machine L...

Location

United States , Mountain View

Salary:

243100.00 - 407200.00 USD / Year

Atlassian

Expiration Date

Until further notice

Requirements

Ph.D. or Master’s degree in Computer Science, Machine Learning, Artificial Intelligence, or a related field
8+ years of experience in machine learning, with a focus on large-scale model development and optimization
Deep expertise in LLM and transformer architectures (e.g., GPT, BERT, T5)
Strong proficiency in Python and ML frameworks such as PyTorch, JAX, or TensorFlow
Experience with distributed training techniques and large-scale data processing pipelines
Proven track record of deploying machine learning models in production environments
Familiarity with model optimization techniques, including quantization, pruning, and knowledge distillation
Strong problem-solving skills and ability to work in a fast-paced, collaborative environment
Excellent communication skills and ability to translate technical concepts for diverse audiences

Job Responsibility

Lead the fine-tuning and post-training optimization of large language models (LLMs) for diverse applications
Develop and implement techniques for model compression, quantization, pruning, and knowledge distillation to optimize performance and reduce computational costs
Conduct research on advanced techniques in transfer learning, reinforcement learning, and prompt engineering for LLMs
Design and execute rigorous benchmarking and evaluation frameworks to assess model performance across multiple dimensions
Collaborate with infrastructure teams to optimize LLM deployment pipelines, ensuring scalability and efficiency in production environments
Stay at the forefront of advancements in LLM technologies, sharing insights, driving innovation within the team, and leading agile development
Mentoring other team members, facilitating within/across team workshops, fostering a culture of technical excellence and continuous learning

What we offer

health coverage
paid volunteer days
wellness resources

Fulltime

Principal Data Scientist

T-Mobile’s Strategy and Corporate Development (S&CD) team is looking for a Princ...

Location

United States , Bellevue; Overland Park

Salary:

127400.00 - 229800.00 USD / Year

T-Mobile

Expiration Date

Until further notice

Requirements

Bachelor's Degree in Quantitative Discipline (math, statistics, economics, computer science, physics, engineering)
Master's/Advanced Degree Quantitative Discipline (math, statistics, economics, computer science, physics, engineering)
7-10 years of industry experience in predictive modeling, data science, and analysis in an ML engineer or data scientist role building and deploying ML models or hands on experience developing deep learning models
7-10 years of Experience articulating and translating business questions and using statistical techniques to arrive at an answer using available data
7-10 years of Experience with data scripting languages (e.g., SQL, Python, R) and Extended experience working with relational database using SQL
4-7 years of Experience writing and speaking about technical concepts to business, technical, and lay audiences and giving data-driven presentations
4-7 years of Experience with statistical methods and advanced modeling techniques. For example- SVM, Random Forest, graph models, Bayesian inference, NLP, Computer Vision, neural networks
4-7 years of Experience with big data architecture and pipeline, Hadoop, Hive, Spark, Kafka, etc
4-7 years of Experience in data visualization
2-4 years Management consulting, investment banking, or corporate strategy

Job Responsibility

Extract, prepare, and model large, complex data sets using a combination of skills, including machine learning theory, mathematics, statistics, and programming
Identify critical and emerging technologies that will support and extend our consumer data, data integration, and quantitative analytic capabilities
Lead the implementation, assessment and standardization of advanced analytics and modeling toolkits for our data science team
Partner with data engineering teams to shape data management strategies, architecture, governance, pipelines, and infrastructure enabling effective modeling environments for data science teams
Provide senior level guidance to the data science and measurement science teams on approach and methodologies
Communicate important information and insights to business leaders using verbal, written, and data visualization skills

What we offer

competitive base salary and compensation package
annual stock grant
employee stock purchase plan
401(k)
access to free, year-round money coaches
medical, dental and vision insurance
flexible spending account
employee stock grants
paid time off
up to 12 paid holidays

Fulltime

Principal AI/ML & Innovation Engineer

We are seeking Principal AI/ML & Innovation Engineer who will be leading initiat...

Location

Puerto Rico , Aguadilla

Salary:

Not provided

Hewlett Packard Enterprise

Expiration Date

Until further notice

Requirements

Bachelor's or master’s degree in computer science, engineering, data science, machine learning, artificial intelligence, or closely related quantitative discipline
Typically, 10-15 years’ experience
Solid understanding of fundamental AI and machine learning concepts, including supervised and unsupervised learning, deep learning, reinforcement learning, natural language processing, computer vision, and statistical modeling
Proficient in implementing and deploying various machine learning algorithms, such as decision trees, random forests, support vector machines, and neural networks
Knowledge of popular machine learning frameworks and libraries like TensorFlow, PyTorch, or sci-kit
Strong understanding of GitHub CoPilot, Cursor, N8N, vibe coding, Windsurf, and similar technologies
Experience in Cloud Infrastructure (AWS, Azure, etc)
Knowledge of Open Source, Linux, etc
Understanding of Devops, SRE
Expertise in deep learning techniques, architectures, and frameworks (e.g., convolutional neural networks (CNN), recurrent neural networks (RNN), generative adversarial networks (GAN), etc.)

Job Responsibility

Designing, developing, and deploying advanced machine learning models and algorithms
Leading research initiatives to explore novel approaches and technologies
Designing the architecture of AI systems and ensuring scalability, performance, and reliability
Collaborating with other teams, such as data scientists, software engineers, and product managers
Providing technical leadership and mentorship to junior engineers
Overseeing and guiding multiple design review sessions across different projects
Partnering with the engineering manager and team lead to establish long-term design and implementation strategies
Leading efforts to incorporate feedback loops and continuous improvement processes
Leading meetings, ensuring efficient progress tracking, issue resolution, and team coordination
Creating and delivering high-level presentations and reports to executive stakeholders

What we offer

Health & Wellbeing
Personal & Professional Development
Unconditional Inclusion

Fulltime

Principal Researcher - Deep Learning

Microsoft Corporation

Location:
United States , Redmond

Category:
Research and Development

Contract Type:
Not provided

Salary:

Job Description:

Job Responsibility:

Requirements:

Nice to have:

Additional Information:

Job Posted:
March 25, 2026

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Microsoft Corporation

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