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Pfizer Logo Pfizer · Research and Development

Principal Packaging Engineer- Drug Product Design & Development

United States, St. Louis - Chesterfield 106000.00 - 171500.00 USD / Year · Job Posted February 20, 2026
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Job Description

We are seeking an accomplished and forward-thinking leader to join our Biotherapeutics Pharmaceutical Research & Development – Drug Product Design & Development (DPDD) organization. In this highly visible role, you will shape the future of packaging and laboratory operations for innovative drug-device combination products, while championing quality, compliance, and continuous improvement. You will lead and inspire a team of packaging engineers and laboratory professionals, serving as both a technical authority and people leader. This role offers the opportunity to influence strategy, drive operational excellence, and play a critical part in advancing products from development through commercialization—ultimately impacting patients’ lives worldwide.

Job Responsibility

  • Provide strategic direction and day-to-day leadership for laboratory operations supporting drug product and combination product development
  • Mentor, develop, and empower a high-performing team
  • Contribute to goal setting, performance reviews, and career development for packaging engineers
  • Act as the subject matter expert for laboratory operations, ensuring compliance with ISO 13485, GMP, and internal quality systems
  • Own equipment calibration and qualification activities
  • Ensure laboratory notebooks and electronic lab notebook (eLN) systems meet procedural, regulatory, and best-practice standards
  • Oversee and review testing activities, protocols, work instructions, lab notebooks, and technical reports for medical devices and combination products
  • Lead component and container closure system selection, qualification, and development activities
  • Author and support regulatory submission content and respond to packaging-related regulatory inquiries
  • Partner closely with Quality, Regulatory, EHS, Facilities, Manufacturing, and Global Workplace Solutions
  • Lead cross-functional initiatives to harmonize laboratory and business processes across teams and sites
  • Support the transfer of new drug products to commercial manufacturing and post-launch support teams
  • Drive continuous improvement initiatives to enhance efficiency, quality, and scalability of lab and design control processes
  • Identify and implement best practices, tools, and strategies that strengthen DPDD capabilities and future readiness

Requirements

  • Bachelor’s degree in Engineering or Science (Packaging, Mechanical, Materials, Biomedical, Chemical, Chemistry, Biochemistry, or related) with 12+ years of relevant experience
  • OR Master’s/MBA with 10+ years of experience
  • OR PhD with 8+ years of experience in pharmaceutical packaging development
  • Strong knowledge of parenteral packaging components and testing equipment (e.g., Instron, ZebraSci, Computrac, plunger movement chambers)
  • Experience in GMP and/or ISO 13485 environments
  • In-depth understanding of global regulatory and quality standards (FDA, ICH, ISO 13485, 11040, 10993, USP/EP/JP compendia, combination product regulations)
  • Ability to interface with regulatory agencies and provide sound technical justifications
  • Demonstrated success leading teams and cross-functional initiatives
  • Excellent written, verbal, and presentation skills
  • Strong project management and stakeholder engagement capabilities
  • Combination of laboratory and office-based work
  • Occasional travel (approximately 5–10%) to other sites, vendors, and conferences

What we offer

  • Participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary
  • Eligibility to participate in our share based long term incentive program
  • 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
  • Paid vacation, holiday and personal days
  • Paid caregiver/parental and medical leave
  • Health benefits to include medical, prescription drug, dental and vision coverage
  • Relocation assistance may be available based on business needs and/or eligibility
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