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Amgen Logo Amgen · IT - Administration

Principal IS Business System Analyst – Real World Evidence

Portugal, Lisbon Employment contract · Job Posted June 02, 2026
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Job Description

Amgen is seeking a Principal Business Analyst to join the Real World Evidence (RWE) Product Team. As a Principal IS Business Systems Analyst at Amgen, you will provide strategic leadership and guidance in analyzing business requirements and designing information systems solutions. You will collaborate with stakeholders to understand business needs, identify system enhancements, and drive system implementation projects. Your extensive experience in business analysis, system design, and project management will enable you to deliver innovative and effective solutions that align with the company's strategic goals.

Job Responsibility

  • Collaborate with System Architects and Product Managers to manage business analysis activities, ensuring alignment with engineering and product goals
  • Capture the voice of the customer to define business processes and product needs
  • Work with Product Managers and customers to define scope and value for new developments
  • Collaborate with Engineering and Product Management to prioritize release scopes and refine the Product backlog
  • Ensure non-functional requirements are included and prioritized in the Product and Release Backlogs
  • Facilitate the breakdown of Epics into Features and Sprint-Sized User Stories and participate in backlog reviews with the development team
  • Clearly express features in User Stories/requirements so all team members and stakeholders understand how they fit into the product backlog
  • Translate complex business and technological needs into clear, actionable requirements for development teams
  • Ensure Acceptance Criteria and Definition of Done are well-defined
  • Stay focused on software development to ensure it meets requirements, providing proactive feedback to stakeholders
  • Develop and execute effective product demonstrations for internal and external stakeholders
  • Maintain accurate documentation of configurations, processes, and changes
  • Serve as a liaison between global DTI functional areas and business clients, prioritizing their needs and expectations
  • Manage a suite of custom internal platforms, commercial off-the-shelf (COTS) software, and systems integrations

Requirements

  • Master’s degree with 8 - 10 years of experience in Life Science/Biotechnology/Pharmacology/Information Systems experience OR Bachelor’s degree with 10 - 14 years of experience in Life Science/Biotechnology/Pharmacology/Information Systems experience OR Diploma with 14 - 18 years of experience in Life Science/Biotechnology/Pharmacology/Information Systems experience
  • Excellent problem-solving skills and a passion for tackling complex challenges in drug discovery with technology
  • Experience with Agile software development methodologies (Scrum)
  • Excellent communication skills and the ability to interface with senior leadership with confidence and clarity
  • Has experience with writing user requirements and acceptance criteria in agile project management systems such as JIRA
  • Demonstrated expertise in a clinical development domain and related technology needs

Nice to have

  • Experience in managing product features for PI planning and developing product roadmaps and user journeys
  • Technical thought leadership
  • Able to communicate technical or complex subject matters in business terms
  • Jira Align experience
  • Knowledge of Cloud technologies and GCP validation
  • Experience of DevOps, Continuous Integration, and Continuous Delivery methodology
  • SAFe for Teams certification (preferred)

What we offer

  • Vast opportunities to learn, develop, and move up and across our global organization
  • Diverse and inclusive community of belonging, where colleagues are empowered to bring ideas to the table, take risks, and act
  • Generous AMGEN Total Rewards Plan comprising healthcare, finance, wealth, and career benefits
  • Flexible work arrangements
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