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Amgen’s Clinical Computation Platform Product Team manages a core set of clinical computation solutions that support global clinical development. This team is responsible for building and maintaining systems for clinical data storage, data auditing and security management, analysis and reporting capabilities. These capabilities are pivotal in Amgen’s goal to serve patients. The Principal IS Architect will define the architecture vision, create roadmaps and support the design and implementation of advanced computational platforms to support clinical development, ensuring that IT strategies align with business goals. The Principal IS Architect will work closely with partners across departments, including CfDA, GDO, CfOR, CfTI, CPMS and IT teams, to design and implement scalable, reliable, and hard-working solutions.
Job Responsibility:
Develop and maintain the enterprise architecture vision and strategy, ensuring alignment with business objectives
Create and maintain architectural roadmaps that guide the evolution of IT systems and capabilities
Establish and enforce architectural standards, policies, and governance frameworks
Evaluate emerging technologies and assess their potential impact on the enterprise/domain/solution architecture
Identify and mitigate architectural risks, ensuring that IT systems are scalable, secure, and resilient
Maintain comprehensive documentation of the architecture, including principles, standards, and models
Drive continuous improvement in the architecture by finding opportunities for innovation and efficiency
Work with partners to gather and analyze requirements, ensuring that solutions meet both business and technical needs
Evaluate and recommend technologies and tools that best fit the solution requirements
Ensure seamless integration between systems and platforms, both within the organization and with external partners
Design systems that can scale to meet growing business needs and performance demands
Develop and maintain logical, physical, and conceptual data models to support business needs
Establish and enforce data standards, governance policies, and best practices
Design and manage metadata structures to enhance information retrieval and usability
Requirements:
Any degree with 13 to 17 years of experience in Computer Science, IT or related field
Proficiency in designing scalable, secure, and cost-effective solutions
Expertise in cloud platforms (AWS, Azure, GCP), data lakes, and data warehouses
Experience in evaluating and selecting technology vendors
Ability to create and demonstrate proof of concept solutions to validate technical feasibility
Strong knowledge of Clinical Research and Development Domain
Experience working in agile methodology, including Product Teams and Product Development models
Nice to have:
Strong solution design and problem-solving skills
Experience in developing differentiated and deliverable solutions
Ability to analyze client requirements and translate them into solutions
Experience with machine learning and artificial intelligence applications in clinical research
Strong programming skills in languages such as Python, R, or Java
Experience of DevOps, Continuous Integration, and Continuous Delivery methodology
Excellent critical-thinking and problem-solving skills
Good communication and collaboration skills
Demonstrated awareness of how to function in a team setting
Demonstrated awareness of presentation skills
What we offer:
Competitive and comprehensive Total Rewards Plans that are aligned with local industry standards