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Principal Epidemiologist

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Allen Lane

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Location:
United Kingdom , London

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Category:
Public Sector

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Contract Type:
Not provided

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Salary:

81000.00 - 117800.00 GBP / Year
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Job Description:

This is an SCS1 grade position at the Medicines and Healthcare products Regulatory Agency (MHRA). The role is strategic, focused on delivering high-impact, cross-cutting initiatives that have the potential to shape the Agency’s future capabilities. By harnessing real-world data, you will pioneer innovative approaches that strengthen the UK’s regulatory science framework. Operating with significant scientific autonomy, the Principal Epidemiologist will act as a thought leader and methodological innovator. The role reports to the Deputy Director of Scientific Data & Insight.

Job Responsibility:

  • Lead the development and implementation of advanced epidemiological methods to transform how the MHRA identifies, evaluates, and mitigates risks associated with medicines and medical devices
  • Deliver high-impact, cross-cutting initiatives that have the potential to shape the Agency’s future capabilities
  • Pioneer innovative approaches that strengthen the UK’s regulatory science framework by harnessing real-world data
  • Act as a thought leader and methodological innovator – driving forward high-profile projects, advising senior leadership, and contributing to the MHRA’s standing as a global leader in regulatory epidemiology
  • Build and maintain strategic partnerships with academic institutions, healthcare organisations, regulators and international bodies
  • Represent the MHRA externally in national and international committees, expert working groups, and collaborative initiatives
  • Work collaboratively with team members and colleagues across the Agency to achieve shared objectives and maximise the impact of their work

Requirements:

  • Doctoral qualification (or equivalent advanced experience) in epidemiology, statistics, or a closely related quantitative discipline
  • Extensive expertise in the design, implementation, and critical appraisal of advanced epidemiological and statistical methods
  • Advanced proficiency in programming and computational epidemiology, with expert-level skills in tools such as Python, R, or Stata for handling large, complex, and linked healthcare datasets
  • Demonstrated leadership in solving complex, strategic challenges, using advanced epidemiological methods, with clear impact on regulatory policy, health system strategy, or major public health initiatives
  • A strong track record of methodological innovation in epidemiological science
  • Internationally recognised expertise in at least one of the following domains: Bayesian methods, Causal inference, Dynamic benefit-risk assessment, Genetic and molecular epidemiology, Machine learning and AI, Simulation-based benefit-risk models, Systems epidemiology, Similar advanced and novel methods, Prescription Sequence Symmetry Analysis
  • Recognised thought leadership, evidenced by publications, invited keynotes, advisory roles, or leadership of expert working groups
  • Proven ability to shape organisational culture and strategic direction
  • Extensive experience communicating complex technical and conceptual material with clarity and influence
  • A sustained record of high-impact scientific publication
  • Deep expertise in the use of real-world data assets, including advanced analytics in a regulatory or public health context
  • Demonstrating the behaviours: Seeing the big picture, Changing and improving, Communicating and influencing
What we offer:
  • Eligibility to the Civil Service pension scheme (employer contribution of 28.97%)
  • Flexible working

Additional Information:

Job Posted:
March 05, 2026

Employment Type:
Fulltime
Work Type:
Hybrid work
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