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Postgrad/postbac in HIV and T cell immunology

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jobRxiv

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Location:
United States , New Haven

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Category:
Research and Development

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Contract Type:
Not provided

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Salary:

Not provided
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Job Description:

The laboratory of Dr. Ya-Chi Ho, MD, PhD at the Department of Microbial Pathogenesis at Yale University is looking for a highly motivated postgraduate student with a strong interest in translational research and immunology. The goal of our lab is to examine mechanisms of HIV persistence and investigate T cell immunobiology involving virology, immunology (including mouse models), molecular biology, single-cell genomics, epigenetics, and bioinformatics. The typical term is 1 year, with extension to the second year if the student makes sufficient progress. The desired start date is June 1, 2026 or earlier.

Job Responsibility:

  • Conduct hypothesis-driven research on important scientific questions
  • Perform scientific interrogations with rigor and responsibility
  • Perform data analysis, interpretation, scientific presentation, and scientific communication
  • Learn literature review, critical thinking, and scientific methods
  • Develop deep and broad knowledge in HIV virology and immunology
  • Develop responsible conduct in wet-lab based research
  • Ask scientific questions and pursue scientific interrogations with strong curiosity, scientific premise, rigor, and reproducibility
  • Process blood and tissue samples from people living with HIV using sterile cell culture techniques in an enhanced biosafety level 2 (BSL2+) setting
  • Examine HIV-host interactions using HIV-1 genomic sequencing, single-cell RNAseq, viral outgrowth cultures, flow cytometry, molecular cloning, CRISPR-mediated gene expression modulation, and bioinformatics analysis
  • Work on mouse models for immunology mechanistic testing
  • Keep lab records, perform careful experimental procedures, follow biosafety procedures, design experiments, perform data analysis, troubleshoot, proactively discuss with lab members and PI, actively search and read relevant literature, present in lab meetings
  • Participate in laboratory maintenance and various collaborative projects with other lab members
  • Follow high standards of rigor, reproducibility, and responsible conduct of research

Requirements:

  • Recent (<2 years) bachelor’s degree in a science discipline (or current undergrad students who will graduate by May 2026)
  • Prior hypothesis-driven wet-lab bench research experience in research labs
  • Experience in sterile cell culture skills and mouse experiments is preferred
  • Individuals who are willing to learn new techniques, lead independent project, read scientific literature autonomously, and who are proficient in multi-tasking are preferred

Nice to have:

  • Experience in sterile cell culture skills and mouse experiments
  • Willingness to learn new techniques, lead independent project, read scientific literature autonomously, and proficiency in multi-tasking

Additional Information:

Job Posted:
January 19, 2026

Employment Type:
Fulltime
Work Type:
On-site work
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