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Postdoctoral Fellowship in Smart Oral Delivery Platforms for Targeted Therapeutics

https://www.csiro.au/ Logo

CSIRO

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Location:
Australia, Brisbane

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Category:
Research and Development

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Contract Type:
Employment contract

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Salary:

99990.00 - 109527.00 AUD / Year

Job Description:

CSIRO Postdoctoral Fellowship focused on developing oral delivery platforms for fragile therapeutics and functional compounds in feed to address antimicrobial resistance and sustainable production systems in animal production

Job Responsibility:

  • Conduct literature reviews to assess current oral delivery technologies and identify key gaps in feed-based delivery of labile therapeutics and bioactives
  • Design, develop and optimise novel oral delivery platforms (e.g. nanoencapsulation, matrix encapsulation and carrier systems) to stabilise and protect labile bioactives during feed processing and digestion
  • Evaluate the potential of low-cost, sustainable materials (e.g., biochar and agricultural by-products) as carrier matrices for oral delivery platforms
  • Conduct in vitro testing of compound stability, release kinetics, and bioavailability using simulated feed manufacturing and digestive models
  • Undertake in vivo validation of delivery technologies in model organisms (e.g. Artemia) and production species (e.g. fish, prawns), assessing therapeutic efficacy, pharmacokinetics, host response, and potential cytotoxicity
  • Apply multi-omics approaches to analyse complex biological datasets and elucidate mechanisms of action at the host–microbe–diet interface
  • Collaborate with cross-disciplinary teams to integrate food technology, feed formulation, processing, and animal health insights into scalable, industry-ready solutions
  • Communicate research findings effectively through peer-reviewed publications, conference presentations, industry forums, and technical reports
  • Deliver innovative and impactful research aligned with CSIRO's vision to reduce antibiotic use, enhance animal health and welfare, and support sustainable high-value protein production

Requirements:

  • A doctorate (or will shortly satisfy the requirements of a PhD) in a relevant discipline area such as animal nutrition, feed science, pharmaceutical sciences, materials science, microbiology, biotechnology, or similar
  • Demonstrated expertise in at least one of the following areas: materials science and biomaterials engineering, pharmaceutical and drug delivery sciences, digestive biology and gut physiology
  • Experience in designing and conducting experiments with scientific rigour, including in vitro simulation models and/or in vivo animal trials relevant to oral delivery and digestive biology
  • Proven ability to analyse complex datasets and apply scientific methodologies effectively

Nice to have:

  • Practical experience or strong understanding of encapsulation technologies and carrier matrix development
  • Experience working with antimicrobial peptides, probiotics, bacteriophages, nanoparticles, or similar bioactive compounds
  • Familiarity with multi-omics approaches and/or data integration methods
What we offer:
  • 15.4% superannuation
  • Flexible work arrangements
  • Range of leave entitlements
  • Career development opportunities

Additional Information:

Job Posted:
September 17, 2025

Expiration:
October 15, 2025

Employment Type:
Fulltime
Work Type:
On-site work
Job Link Share:
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