CrawlJobs Logo

PK Scientist

iconplc.com Logo

iconplc

Location Icon

Location:

Category Icon
Category:
Research and Development

Job Type Icon

Contract Type:
Not provided

Salary Icon

Salary:

Not provided
Save Job
Save Icon
Apply Position

Job Description:

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development. We are seeking an experienced Clinical Pharmacology professional to support protocol development and pharmacokinetic/pharmacodynamic (PK/PD) analysis across Phase I–IV clinical trials as PK Scientist. This role involves protocol writing, non-compartmental analysis (NCA), and clinical pharmacology reporting while collaborating with cross-functional teams within a regulated clinical development environment.

Job Responsibility:

  • Author and coordinate development of clinical pharmacology trial protocols and ensure timely review, approval, and issuance
  • Perform preliminary, interim, and final PK, PD, and PK/PD analyses using non-compartmental methods
  • Develop the Clinical Pharmacology Analysis Plan (CPAP) and generate data handling logbooks prior to final NCA
  • Create tables, listings, and figures and contribute to drafting clinical pharmacology sections of Clinical Study Reports (CSRs)
  • Conduct QC review of protocols, analyses, datasets, and all deliverables while ensuring compliance with SOPs, ICH-GCP, and regulatory requirements

Requirements:

  • Bachelor’s degree or higher in a scientific discipline (or equivalent experience) with strong written and verbal communication skills
  • 1+ years of relevant experience in clinical pharmacology, including exposure to clinical study protocols and regulatory requirements
  • Working knowledge of data analyses software packages
  • Hands-on experience with Phoenix WinNonlin and working knowledge of R for PK/PD analysis (Experience with R is an advantage)
  • Basic knowledge of noncompartmental PK analysis and statistical principles
  • Understanding of clinical trial data structures and experience collaborating with Data Management, Biostatistics, and CRO partners
What we offer:
  • Various annual leave entitlements
  • A range of health insurance offerings to suit you and your family’s needs
  • Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead
  • Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being
  • Life assurance
  • Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others

Additional Information:

Job Posted:
March 18, 2026

Work Type:
Remote work
Icon
iconplc - All Job Offers
Job Link Share:
Copy Link Icon
Facebook Icon Twitter Icon LinkedIn Icon

Looking for more opportunities? Search for other job offers that match your skills and interests.

Briefcase Icon

Similar Jobs for PK Scientist

Scientist, LCMS PK Bioanalytical

An exciting opportunity is available for a Scientist to join the PK LCMS group i...
Location
Location
United States , Andover
Salary
Salary:
79400.00 - 128500.00 USD / Year
pfizer.de Logo
Pfizer
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • MS with 4 to 6 years of relevant work experience, ideally mostly in industry (or BS/BA with 6 to 8 years of experience)
  • Expertise in development, characterization, and implementation of bioanalytical LCMS assays
  • Experience in the operation and troubleshooting of LCMS instrumentation and associated operating/data analysis software including Skyline, Analyst, Sciex OS and Xcalibur
  • Hands-on experience of biological sample preparation procedures for quantitative LCMS assays on biotherapeutics
  • Knowledge of writing scripts to set up methods for automated liquid handler system
  • Knowledge of protein biochemistry of therapeutic antibodies, fusion proteins or ADCs
Job Responsibility
Job Responsibility
  • Responsible for the development, qualification and implementation of PK/PD assays using mass spectrometry in support of discovery and preclinical projects
  • Works with group leads or other discovery and regulated bioanalytical team members and project team members to accomplish goals
  • Participates in technology development and implementation by exploring new workflows, including automation, high throughput sample preparation and instrumentation in protein quantitation, to expand the group’s PK LCMS bioanalytical capabilities
  • Participate in all phases of mass spectrometry laboratory operations including technology evaluations, the development of sample preparation and separation methods, data analysis, interpretation, reporting and follow up discussions with the project teams on utilizing the data in appropriate decision making
  • Ensure all tasks and responsibilities are carried out according to scientific and ethical standards e.g. responsible for electronic notebook record keeping
  • QC and peer review of data and reports
What we offer
What we offer
  • 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
  • paid vacation, holiday and personal days
  • paid caregiver/parental and medical leave
  • health benefits to include medical, prescription drug, dental and vision coverage
  • bonus target of 7.5% of the base salary
  • Relocation assistance may be available
  • Fulltime
Read More
Arrow Right

Global Development Product Lead

Leads multiple cross functional oncology product teams from pre-clinical candida...
Location
Location
United States , La Jolla; Cambridge; Bothell; South San Francisco; New York City
Salary
Salary:
295900.00 - 478800.00 USD / Year
pfizer.de Logo
Pfizer
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • MD or MD-PhD with 10+ years of industry experience in oncology drug development is preferred, track record in oncology clinical research including early phase drug development
  • Clinical oncology experience: Board certification in oncology preferred
  • Significant industry leadership experience in clinical, translational or basic research in biomedical sciences or one of the disciplines related to drug development
  • Understanding of related disciplines (e.g., biostatistics, regulatory, pre-clinical pharmacology, pharmaceutical sciences)
  • Demonstrated scientific productivity (publications, abstracts, etc.)
  • Proven scientific writing skills and good communication skills
  • Proven leadership skills with ability to defend the clinical plan at governance meetings is essential
  • Capacity to adapt to a fast-paced and changing environment
  • Demonstrated history of effective leadership
  • including cross functional and matrixed teams, managing direct reports when applicable, and experience in seeking and maintaining alignment with cross-functional leaders
Job Responsibility
Job Responsibility
  • Leads multiple (~2-4) cross functional oncology product teams from pre-clinical candidate nomination (CAN) through Phase 1-2 clinical development and proof of concept (POC) stages
  • In close collaboration with functional experts on the product teams, drives the effective integration of an end-to-end cross functional molecule strategy and risk mitigation plan and ensures delivery of data-driven milestones through successful risk identification and mitigation
  • Support clinical trials and the development strategy for early development assets and lead development programs across multiple functions within Pfizer Oncology, as well as represent the program with the external clinical community
  • Develop clinical development plan from first in human clinical trial to proof-of-concept, including assessment of appropriate combinations, as well as evaluation of potential predictive and pharmacodynamics biomarker plans
  • To ensure the cross-functional components of the product plans including clinical expertise are provided to project teams, including medical monitoring of clinical trials
  • Substantial support of CDP development and diligence for external innovation activities
  • Lead key enterprise level cross-functional workstreams to accelerate R&D decision making
  • Lead, develop and execute strategic development for early development assets
  • Ensure timely execution and delivery of product milestones within budget
  • Communicate with executive management and governance committees to address program needs and provide recommendations
What we offer
What we offer
  • Participation in Pfizer’s Global Performance Plan with a bonus target of 30.0% of the base salary
  • Eligibility to participate in our share based long term incentive program
  • 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
  • Paid vacation, holiday and personal days
  • Paid caregiver/parental and medical leave
  • Health benefits to include medical, prescription drug, dental and vision coverage
  • Relocation assistance may be available based on business needs and/or eligibility
  • Fulltime
Read More
Arrow Right

Scientist / Senior Scientist, DMPK

An exciting opportunity is available for an enthusiastic and highly-skilled Scie...
Location
Location
United States , San Francisco Bay Area; San Diego
Salary
Salary:
132500.00 - 247200.00 USD / Year
altoslabs.com Logo
Altos Labs
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD in Chemistry, Biology, Pharmaceutical Sciences, or a related field and 3+ years of relevant work experience
  • Strong fundamental knowledge of DMPK and ADME
  • Working knowledge of ADME assays and bioanalysis, leveraged to design studies and interpret data
  • Ability to evaluate in vitro-in vivo correlation of drug candidates across preclinical species
  • Ability to generate NCA and compartmental PK models
  • general knowledge of mechanistic modeling concepts (e.g., PBPK)
  • Ability to communicate DMPK results in a timely, clear, and impactful manner to non-DMPK scientists
  • Exceptional organizational skills, attention to detail, time management, and ability to work independently and collaboratively
  • Willingness to gain new knowledge and apply it to support multiple therapeutic modalities
Job Responsibility
Job Responsibility
  • Serve as the DMPK representative on cross-disciplinary preclinical project teams, providing strategic and data-driven DMPK guidance to advance portfolio programs
  • Plan, manage, and oversee ADME and PK studies executed with external CRO partners
  • Partner with Medicinal Chemistry to develop ADME- and PK-driven SAR strategies to optimize candidate properties and progression
  • Collaborate with Pharmacology and the internal DMPK bioanalysis group to design, execute, and interpret preclinical PK/PD, target engagement, and efficacy studies
  • Calculate the projected efficacious human dose to support IND-enabling development and regulatory submissions
  • Provide DMPK support to early-stage, pre-portfolio discovery programs, helping shape strategy and experimental plans
  • Advise and train the DMPK bioanalysis team to support internalization and implementation of select ADME assays
  • Stay current on emerging DMPK science and best practices through literature review and participation in relevant scientific meetings
  • Fulltime
Read More
Arrow Right

Scientific Associate Director - Pharmacokinetics and Drug Metabolism

In this vital and exciting role, you will oversee Pharmacokinetics and Drug Meta...
Location
Location
India , Hyderabad
Salary
Salary:
Not provided
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • PhD in Pharmacokinetics, Pharmaceutical Sciences, Engineering, or related fields with equivalent professional degrees and 12+ years of experience in the Biotechnology/Pharmaceutical Industry
  • Solid technical experience with the application of SM in vitro/in vivo ADME and pharmacokinetics fundamentals to drug discovery projects
  • Ability to drive the progression of SM discovery and development within project teams
  • Expertise with in vitro ADME, in vivo ADME, PK/PD etc
  • Experience in supporting preclinical components of regulatory documentations
  • Excellent interpersonal, technical, and communication skills
  • Past experience as a laboratory scientist in a pharma or biotech environment
  • Excellent written and oral communication skills, attention to detail and accuracy, and interpersonal skills
  • Record of scientific contributions through peer-reviewed articles and external presentations
Job Responsibility
Job Responsibility
  • Lead/mentor a team of scientists involved in ADME characterization of small molecules
  • Directly responsible for leading a team of scientists involved in undertaking mechanistic in vitro ADME assays
  • Develop/implement novel tools to efficiently support mechanistic ADME work
  • Oversee activities/establish workflows for small molecule bioanalytical and ADME screening teams
  • Serving as a subject matter expert of small molecule ADME to support the programs and recommend strategies to PKDM project team representatives to reduce/mitigate risks due to metabolism
  • Collaborate with scientists across our PKDM scientific community
  • Leveraging specialized ADME/PK skills such as in vitro ADME, in vivo ADME, biotransformation, PK/PD, to impact project progression and decision-making
  • Contributing to the analysis of pre-clinical ADME and PK data for IND and NDA filings and documenting these analyses in appropriate reports
  • Building close relationships with partner functions
Read More
Arrow Right
New

Account Executive, Mid-Market Sales

We’re looking for an Account Executive, Mid-Market to help us develop and close ...
Location
Location
Canada , Toronto
Salary
Salary:
57700.00 - 75000.00 CAD / Year
hootsuite.com Logo
Hootsuite
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Intermediate level experience in B2B sales OR 3+ years of lead generation/business development representative experience (experience in software considered an asset)
  • proven ability to achieve or exceed assigned quotas
  • Ability to focus on client business value, return on investment, and customer solutions (not features-focused selling)
  • Experience crafting sales plans for your vertical/territory and building/executing on your account/territory plans
  • Open Communication: clearly conveys thoughts, both written and verbally, listening attentively and asking questions for clarification and understanding
  • Commitment to Results: Consistently achieving results, demonstrating high performance and challenging self and others to deliver results
  • Customer Focus: Demonstrates a desire to proactively help and serve internal/external customers meet their needs
  • Negotiation: Successfully obtains commitment to a solution or idea, while maintaining integrity and relationships
  • Perseverance: Pursues everything with energy, drive, and a need to finish—doesn’t give up
Job Responsibility
Job Responsibility
  • Successfully acquire new mid-market customers within our landmark industries by responding and actioning internal leads in order to achieve individual quota targets
  • Navigate sales cycles from value creation to negotiation and closing, and present the value of our solutions to prospective customers. Forecast and close new business revenue every month
  • Proactively seek out insightful market and industry information in order to effectively develop rapport with mid-market customers. Recommend relevant solutions by offering a unique product mix from the range of Hootsuite products to solve clients business challenges
  • Recommend appropriate third party partner solutions to meet customer needs and build a differentiated pitch for our customers
  • Deliver product presentations and demos to potential customers, showcasing a range of solutions that provide maximum benefit to the customer. Complete RFI/ RFP and other supplier technical requirement documents
  • Partner with our pre & post sales teams to navigate roadblocks and objections, ensuring customer success and long term value for the customer
  • Manage, track and report sales activities and results through Salesforce, Sales Navigator and 6Sense
  • Facilitate a warm handoff to the implementation and customer teams following the close of the initial customer sale to ensure a smooth customer transition and onboarding
  • Engage and educate existing commercial customers on Hootsuite's value proposition
  • maximize the value of each account by aligning customer's unique needs and overall goals on social media
What we offer
What we offer
  • Health insurance including medical, dental, vision, life/disability insurances
  • Employee and Family Assistance Program
  • Group RRSP plan with a company match of up to 4% of base salary (Canada)
  • 401k Plan with a company match (up to 4% of base salary) (US)
  • Global Parental Leave: 26 weeks of full and partially paid leave for permanent employees employed for a minimum of 12 months
  • Fulltime
Read More
Arrow Right
New

Concierge Agent

Join our pre-opening Front Office team as Concierge Agent at Four Seasons Resort...
Location
Location
Saudi Arabia , Amaala
Salary
Salary:
Not provided
fourseasons.com Logo
Four Seasons
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Previous experience in guest services or concierge roles within luxury hospitality, ideally including pre-opening exposure
  • Strong local knowledge and passion for creating memorable guest experiences
  • Excellent communication and interpersonal skills
  • Professional presentation and problem-solving abilities
  • Suitable candidates must be eligible to work in Saudi Arabia
  • Fluency in English is essential
Job Responsibility
Job Responsibility
  • Assist with pre-opening tasks including establishing guest service standards, local vendor partnerships, and concierge systems setup
  • Provide personalized recommendations and assist guests with reservations, transportation, tours, activities, and special requests
  • Coordinate with departments and external partners to fulfill guest needs efficiently
  • Maintain accurate guest profiles and preferences to support personalized experiences
  • Handle VIP requests and ensure all guests receive attentive, thoughtful service throughout their stay
  • Manage guest feedback and respond professionally to any service concerns
  • Maintain up-to-date knowledge of local attractions, dining options, and unique experiences
  • Support in the creation and refinement of concierge procedures and guest service standards
What we offer
What we offer
  • Competitive salary in a tax-free environment
  • Housing and transportation
  • 30 days of vacation plus public holidays
  • Paid home leave tickets
  • Complimentary meals and uniform cleaning
  • Medical and life insurance
  • Employee Assistance Program and worldwide complimentary room nights
  • Opportunities for growth and development
  • Fulltime
Read More
Arrow Right
New

Alloy Wheel Repair Technician

Sytner Jaguar Land Rover Northampton currently has a great opportunity available...
Location
Location
United Kingdom , Northampton
Salary
Salary:
Not provided
sytnerworcesterbmw.co.uk Logo
Sytner BMW Worcester
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Previous experience as an Alloy Wheel Repair Technician is essential
  • Experience in a similar Bodyshop environment is beneficial
  • Ability to operate efficiently in a fast-paced environment
  • Passionate to deliver the highest possible standard of repair with strong attention to detail
  • Strong time management and organisational skills
  • Ability to ensure assigned jobs are completed within estimated times
Job Responsibility
Job Responsibility
  • Carry out repairs on vehicles
  • Carry out repairs to a high level of quality in set timescales
  • Repairs include standard silver wheels, full-colour change, cosmetic diamond-cut repairs and special effect finishes
  • Work a variety of flexible patterns which can typically include weekends
What we offer
What we offer
  • Enhanced Holiday Entitlement – 33 days inc. bank holidays
  • Industry-leading Maternity, Paternity and Adoption Pay
  • Career Development
  • Recognition of Long Service every 5 years
  • Discounted Car Schemes
  • High Street Discounts
  • Discounted Gym memberships
  • Cycle to work scheme
  • One day a year paid voluntary / community work
  • Colleague Discount on Cars
  • Fulltime
Read More
Arrow Right
New

Reservations Agent

The PBX Operator role primarily serves as the communications hub for our restaur...
Location
Location
United States
Salary
Salary:
25.00 - 28.00 USD / Hour
lavalavabeachclub.com Logo
Lava Lava Beach Club
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Contributes to building and maintaining a positive work culture at all times
  • Flexible schedule, especially during busy seasons
  • Ability to communicate effectively and work well with others
  • Ability to remain calm, prioritize and multitask in a fast-paced environment
  • Ability to handle guest requests and needs in a professional and pleasant manner
  • Remains calms /productive in a fast-paced environment
  • Can sit for long periods of time (majority of shift)
  • Can bend, twist, squat, kneel, reach overhead, and walk safely
  • Can safely adhere to sanitation/safety protocol at all times
  • Contributes to building and maintaining a positive work culture at all times
Job Responsibility
Job Responsibility
  • Answer incoming calls on a multi-line phone system promptly and professionally
  • Manage reservations for all five restaurant locations, ensuring accurate booking, confirmations, modifications, and cancellations
  • Use reservation systems (e.g., OpenTable and other internal platforms) to track and optimize table availability
  • Send confirmation messages to guests via phone, text, or email as appropriate
  • Coordinate reservation changes with restaurant hosts and managers in real-time
  • Provide clear, courteous information to guests about menus, hours, locations, special events, and policies
  • Handle guest inquiries and requests, escalating to management when necessary
  • Resolve reservation conflicts and guest concerns with professionalism and efficiency
  • Greet guests who call and interact with warmth and a ‘Hawaiian hospitality’ mindset
  • Collaborate with on-site staff at each location to ensure seamless guest experiences
  • Fulltime
Read More
Arrow Right
Jobs by Category
Art and Entertainment Jobs Banking Jobs Call Center Jobs Construction Jobs Consulting Jobs Customer Service Jobs Education Jobs Energy Jobs Finance Jobs Gastronomy Jobs Health and Beauty Jobs Hospitality and Tourism Jobs Human Resources Jobs Insurance Jobs IT - Administration Jobs IT - Software Development Jobs Legal Jobs Logistics Jobs Manufacturing Jobs Marketing, Digital Marketing, SEO, SEM Jobs Media Jobs Nursing Jobs Office Administration Jobs Pharmacy Jobs Physical Work Jobs Public Relations Jobs Public Sector Jobs Purchasing Jobs Quality Control Jobs Real Estate Jobs Research and Development Jobs Sales Jobs
Job Positions Jobs by Country
United States Jobs United Kingdom Jobs India Jobs Canada Jobs Australia Jobs Germany Jobs Ireland Jobs Poland Jobs
Company
Blog About Us Contact
Follow Us
Facebook
X (Twitter)
LinkedIn
Instagram
CrawlJobs Group
ITFlashcards AllDevBlogs
© 2026 CrawlJobs Ltd. All Rights Reserved
Terms & Conditions Privacy Policy