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The University of Kansas Health System Logo The University of Kansas Health System · Health and Beauty

Physician - Immune Effector Cell Therapy- Clinician Scientist (BMT)

United States, Westwood · Job Posted February 20, 2026
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Job Description

The University of Kansas Health System, Kansas Cancer Center (an NCI-Designated Comprehensive Cancer Center), is seeking a Clinician Scientist in immune-effector cell therapy to join the Division of Hematologic Malignancies & Cellular Therapeutics. We are the region's largest BMT and Cellular Immunotherapy program in Kansas. The candidate will have access to world- class resources including a new cancer center under construction. This is an opportunity to shape the future of cancer immunotherapy by driving translational research at the interface of discovery, preclinical development, and early-phase clinical trials. The successful candidate will advance next-generation approaches, including CAR-T/NK therapies, engineered macrophages/monocytes, and combination immunotherapies for hematologic and solid tumors.

Job Responsibility

  • Establish an innovative and externally funded research program
  • Design, lead and execute translational studies in immune-effector cell therapy (e.g., CAR constructs, BiTEs, “armored” cells, logic-gated circuits) that enable generation of patentable IEC intellectual property
  • Recruit additional faculty to expand research within the IEC program
  • Design and oversee in vitro functional assays (killing, cytokine profiling, spectral flow, scRNA-seq/CITE-seq) and in vivo preclinical efficacy/toxicity models
  • Collaborate with KUCC’s cGMP manufacturing, the Institute for Advancing Medical Innovation (IAMI), Clinical Trials Office, Pathology, and Biostatistics to advance First-in-Human, enabling investigational new drug submissions to FDA and lead/participate in IEC early phase clinical trials
  • Develop and validate analytical/quality assays (potency, identity, vector copy number, sterility/mycoplasma, off-target/tropism assessments)
  • Contribute to the preparation of regulatory documentation (IACUC/IRB, Biosafety, IND/IDE modules), study protocols, and clinical correlative science plans
  • Mentor trainees (graduate students, residents, postdocs and fellows) as well as junior faculty and coordinate cross-functional project teams
  • Disseminate results via manuscripts, conference abstracts, and grant applications (NIH, LLS, foundations)

Requirements

  • MD or PhD in Immunology, Hematology/Oncology
  • Cancer Biology, Bioengineering, or related field
  • 2–5 years post-degree research experience in immune-effector cell therapy or closely related area
  • Hands-on expertise in cell engineering (viral/non-viral delivery
  • CRISPR or equivalent), primary T/NK cell culture, and functional immunology assays
  • Previous extramural funding: i.e., K award, R21, DOD
  • Demonstrated track record of impactful publications and team-based science

What we offer

  • Recent increase in overall compensation package
  • Generous retirement contribution
  • Relocation assistance
  • Health, dental, vision insurance
  • CME allowance
  • LTD/STD and Life insurance
  • Professional liability insurance
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