PhD Program: Multimodal early response assessment in radiotherapy

In addition to therapy guidance based on objective diagnostic assessment, patient reported outcome measures (PROMs) may also serve as reliable indicators for early response assessment and even an optimal stopping in radiotherapy. The main objective of the project is to develop a framework for multimodal early response assessment in radiotherapy. Within this framework, the usability of clinical data, radiological imaging data, and patient-reported outcome data for the prediction of radiotherapy response and clinical outcome will be assessed for lung cancer. In parallel, the project aims at the establishment of a robust data collection, storage, and management framework. Furthermore, oesophageal sparing in thoracic proton therapy will be clinically validated through early response assessment during a secondment at Massachusetts General Hospital (MGH).