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Ophthalmology Bioassay Senior Scientist

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SRG

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Location:
United Kingdom , Nottingham

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Category:
IT - Software Development

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Contract Type:
Not provided

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Salary:

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Job Description:

We are seeking an Ophthalmology Bioassay Senior Scientist to join a growing, innovative CRO environment focused on developing next-generation human-relevant disease models. This role sits at the forefront of moving drug discovery away from traditional animal models, with a strong emphasis on advanced in vitro systems, including iPSC-derived models and 3D organoids for ocular diseases. You will play a key role in building and developing capability in ophthalmology, contributing to both project delivery and the longer-term growth of this area of the business. This is an excellent opportunity for someone who enjoys combining hands-on lab work, scientific innovation, and commercial impact.

Job Responsibility:

  • Ocular Model Development: Develop and optimise human-relevant ocular disease models
  • Design and implement iPSC-derived systems, including retinal and epithelial models
  • Contribute to the development of complex 3D organoid and co-culture systems
  • Assay Development & Delivery: Design and execute bioassays relevant to ocular disease, including: Imaging and fluorescence-based assays, Immunoassays, Functional and translational assays
  • Analyse and interpret experimental data and present findings clearly to stakeholders
  • Molecular & Cell Biology: Apply molecular biology techniques including: Gene knockdown approaches (e.g. siRNA, shRNA)
  • Work with primary cells, cell lines, and stem-cell derived models
  • Support development of increasingly complex and physiologically relevant systems
  • Project Delivery & Growth: Support delivery of CRO projects across drug discovery programmes
  • Troubleshoot experimental challenges and drive continuous improvement
  • Contribute to building and scaling ophthalmology capability, including future team growth
  • Engage with clients and support scientific discussions where required

Requirements:

  • Experience working with iPSC-derived systems and/or 3D organoid models (critical)
  • Strong laboratory experience across bioassays, imaging, and molecular biology techniques
  • Experience working with ocular models or strong transferable cell biology experience
  • A proactive, problem-solving mindset with the ability to work independently

Nice to have:

  • PhD in Ophthalmology, Cell Biology, Stem Cell Biology, or a related discipline
  • Experience in a CRO or fast-paced applied research environment
  • Exposure to replacing or reducing animal models with human-relevant systems
  • Interest in helping build or grow a new scientific capability or team

Additional Information:

Job Posted:
May 15, 2026

Employment Type:
Fulltime
Work Type:
On-site work
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