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Pfizer Singapore is recruiting permanent employees for manufacturing site expansion of PFIZER ASIA MANUFACTURING PTE LTD (PAMPL) in Singapore. Your expertise in the manufacturing domain will help in analyzing and designing a sequence of operations and workflow to improve the company's production facilities within regulations and Good Manufacturing Practices. You will be involved in activities, such as process monitoring, safety and environmental improvements, process reliability improvements, validation, and technology transfers. You will also conduct studies pertaining to cost control and reduction, inventory control, and production record systems. On the basis of these studies, you will develop and implement plans and programs for facility modifications and revisions to operating methods. As an associate, your focus on the job will contribute in achieving project tasks and goals. Through your domain knowledge and commitment, you will create a collaborative teaming environment for your colleagues.
Job Responsibility:
Support plant operations in the end to end manufacture (inclusive of changeover) of Active Pharmaceutical Ingredients (APIs) in compliance with Good Manufacturing Practices (GMP) and Standard Operating Procedures (SOPs)
Collaborate cross-functionally to ensure safety, quality, and operational investigations are thoroughly conducted and reported in a timely manner
Contribute to continuous improvement initiatives, including IMEX activities and the development, implementation, and periodic review of documentation that enhances operational effectiveness and regulatory compliance
Support all aspects of manufacturing operations while ensuring full compliance with environmental, health, and safety (EHS) regulations
Maintain a state of perpetual safety and GMP compliance on the shop floor, ensuring audit-readiness at all times
Execute production, pre-maintenance, and post-maintenance intervention activities to meet manufacturing targets and reduce equipment downtime
Ensure that pre-manufacturing checks are performed safely, compliantly in order to meet manufacturing plan
Review operational tasks in alignment with Manufacturing Standard Work (MSW) and Operation Standard Work (OSW) to optimize workflow efficiency
Lead/participate in troubleshooting activities for processing issues and deviations, collaborating cross-functionally to drive immediate and preventive actions to meet manufacturing targets and reduce equipment downtime
Lead/contribute to EHS and quality investigations, generate reports, and drive resolution of issues identified during operations, batch record review, cleaning instructions review and associated manufacturing documentation
Drive Continuous Improvement (CI) initiatives using the Plan-Do-Check-Act (PDCA) methodology to enhance safety, quality, and productivity
Lead/support the development of risk assessments and job safety assessments (JSAs)
participate in HAZOP reviews as needed
Author and review Standard Operating Procedures (SOPs)
ensure SOPs remain current and compliant
Assist in commissioning, qualification, and validation (CQV) activities to support new equipment and process readiness
Participate as a member of the emergency response team (ERT) when necessary
Development and review of changeover cleaning documentation and maintaining cleaning validation status
Development of changeover cleaning schedule and communication with cross functional departments for timely release of equipment for production
Support manufacturing campaigns and changeover cleaning on rotating shift basis, as required
Provide technical guidance for management of alarm responses and ensure alarm response is timely, appropriate and assessed as per SOP. Ensure that interlock bypass is performed safely and compliantly as per SOP
Conduct hands on training including Structured On the Job Training (SOJT), Instructor Led Training (ILT), Job Safety Analysis (JSA), SOPs
Perform structured gemba on operational activities for continuous improvement opportunities and active participation in good save initiative
Requirements:
Degree in Engineering, preferably in Chemical Engineering or Degree in Science
Preferably, 2-3 years’ experience in a relevant manufacturing environment. Fresh graduates considered.