Msat Scientist I - Bioconjugation Job at Proclinical (Bristol)

Job Description

Proclinical is seeking an MSAT Scientist I - Bioconjugation to support the transfer, execution, and ongoing optimization of bioconjugation processes, including ADCs and AOCs, within a cGMP manufacturing environment. Drive the science behind next‑generation bioconjugates-where precision meets transformative medicine.

Job Responsibility

Adhere to cGMP, GDP, GLP, FDA, and ICH requirements and internal procedures
Support technology transfer activities from Process Development or external partners into manufacturing, including document review and execution readiness
Assist in authoring and revising batch records, SOPs, BOMs, and other GMP documentation
Provide on-the-floor manufacturing support during batch execution, including troubleshooting under supervision
Contribute to deviation investigations, root cause analysis, and CAPA implementation with guidance from senior staff
Collect, trend, and analyze data to support process performance and continuous improvement
Participate in process characterization and scale-up activities
Support preparation and execution of PPQ and validation activities as assigned
Maintain knowledge of raw materials, consumables, and single-use assemblies used in manufacturing
Assist in developing training materials and updating process documentation
Collaborate with Manufacturing, Quality, Engineering, and Supply Chain teams
Document activities clearly and accurately in accordance with GDP standards
Present data and findings to internal teams with guidance from senior MSAT staff
Perform other duties as assigned

Requirements

Degree in Biochemistry, Chemical Engineering, Pharmaceutical Sciences, or related field
Basic understanding of cGMP manufacturing environments
Exposure to bioconjugation processes such as ADCs or AOCs preferred but not required
Familiarity with purification techniques like TFF and chromatography (Protein A, IEX, HIC) is a plus
Understanding of aseptic techniques and single-use systems is advantageous
Strong attention to detail and documentation practices
Ability to follow technical instructions and adapt quickly in a fast-paced environment
Basic data analysis skills using Excel or similar tools
Effective communication skills and ability to work in cross-functional teams
Preferred experience with high-potency APIs, process validation, PPQ, and commercial tech transfer
Familiarity with regulatory expectations for complex biologics and bioconjugates is a plus
Ability to stand, sit, and walk for extended periods
Occasionally lift and move objects up to 30 pounds
Perform physical activities such as climbing, stooping, kneeling, and crouching
Visual abilities including near and far sight, color vision, and focus
Ability to gown into ISO 7-8 suites and adhere to gowning policies

Nice to have

Exposure to bioconjugation processes such as ADCs or AOCs
Familiarity with purification techniques like TFF and chromatography (Protein A, IEX, HIC)
Understanding of aseptic techniques and single-use systems
Preferred experience with high-potency APIs, process validation, PPQ, and commercial tech transfer
Familiarity with regulatory expectations for complex biologics and bioconjugates

Proclinical - All Job Offers

Select Country

Msat Scientist I - Bioconjugation

Job Description

Job Responsibility

Requirements

Nice to have

Looking for more opportunities?

Msat Scientist I - Bioconjugation

Software Engineer

Ks2 Teacher

Reservation Agent

Mobile Associate - Retail Sales

Hardware Software Systems Engineer

Staff Pharmacist

Reservation Agent

Secondary SEN Teaching Assistant

Our AI answers in your language