Mechanistic Modeling Specialist Job at Danaher Corporation (Karlsruhe)

Dmpk Modeller

You will join a DMPK drug discovery team in Spain to influence how we translate ...

Location

Spain , Madrid

Salary:

60525.00 - 100875.00 EUR / Year

GSK

Expiration Date

Until further notice

Requirements

Degree in Pharmacology, Pharmaceutics, Pharmacokinetics, Mathematics, Bioengineering, or a related discipline
Practical experience in population PK, PBPK, or mechanistic PK/PD modelling in a biopharma setting
Hands-on experience with modelling software such as, Matlab (symbiology), Monolix, Simcyp, GastroPlus, or equivalent
Experience translating in vitro and preclinical data to humans
Strong written and verbal communication skills in English
ability to explain modelling outcomes to non-specialists
Experience working in cross-functional project teams

Job Responsibility

Lead development and application of pharmacokinetic and pharmacokinetic-pharmacodynamic (PK/PD) models for small molecules and other modalities to inform project decisions
Design and deliver translational modelling strategies, including dose prediction and human exposure projections
Assess and quantify drug-drug interaction (DDI) risk using in vitro-in vivo translation and modelling approaches
Communicate model assumptions, results and uncertainty clearly to cross-functional teams and governance bodies
Mentor and coach colleagues on modelling methods, good practices and scientific interpretation
Contribute to regulatory and internal documents with clear, evidence-based modelling narratives

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

Python Developer

Take Your Career to the Next Level with Amaris Consulting as a Python Developer!...

Location

Spain

Salary:

Not provided

Amaris Consulting

Expiration Date

Until further notice

Requirements

+4 years of experience as a Python Developer
Experience in the pharmaceutical or life sciences industry, particularly in digital transformation or data integration projects
Strong proficiency with Python, FastAPI/Flask, and RESTful APIs for backend development
Experience with one or more frontend frameworks (React.js or Angular)
Solid knowledge of cloud platforms (AWS, Azure, or GCP) and version control tools such as Git
Familiarity with containerization technologies (Docker and Kubernetes) and CI/CD pipelines
Proven experience with microservices architecture and web services
Advanced proficiency in English (written and spoken) – mandatory
Strong problem-solving skills and ability to work both independently and as part of a distributed, cross-functional team

Job Responsibility

Integrate mechanistic and data-driven models on the platform by restructuring and migrating original code to align with SMART PD requirements, functionalities, and user interface
Collaborate closely with domain users (i.e., process experts, subject matter experts, and modelling specialists) to gather requirements and translate them into technical solutions
Develop and extend features of SMART PD to significantly improve user adoption, usability, and satisfaction
Write robust, maintainable, well-documented, and production-ready code following best practices
Execute UX research and feedback loops to understand how features impact and improve the experience of scientific and operational users

What we offer

Fast career growth through a personalized development path and regular salary assessments
Upskill with our Technology Academy, Udemy for Business, language classes (English, Spanish, German), webinars, and technical workshops
Take control of your training with a personal annual learning budget and company-sponsored certifications (e.g., AWS, Kubernetes, Docker)
Fully remote work with flexible hours and digital collaboration tools
Excellent social benefits: private health insurance, meal vouchers, transportation allowance, and childcare support
WeCare programme: dedicated support for employees in personal or professional critical situations
International exposure working on high-impact projects in the pharmaceutical and life sciences sectors

Fulltime

Research Trainee/Research Associate, Biology

Join Enveda as an Research Trainee/ Research Associate, Biology in Hyderabad, In...

Location

India , Hyderabad

Salary:

Not provided

Enveda

Expiration Date

Until further notice

Requirements

M.Pharm/M.S in Pharmacology with 0-2 years of research experience
Experience in small animal handling, dosing, dissections, and tissue processing
Strong interpersonal, problem-solving, and communication skills

Job Responsibility

Conduct in vivo efficacy and mechanistic studies for new chemical entities (NCEs)
Establish and validate new in vivo disease models and biomarkers
Analyze data statistically and deliver results timely for informed decision making
Collaborate with discovery specialists and disease area scientists

What we offer

Culture
Medical
Block Leaves
Work-Life Harmony

Fulltime

Resident Assistant

If you’re looking for a job that goes beyond the basics to deliver purpose and j...

Location

United States of America , Hillsboro

Salary:

18.00 - 20.00 USD / Hour

Leisure Care

Expiration Date

Until further notice

Requirements

Demonstrated experience in a caregiving role
Current CNA a plus!

Job Responsibility

Assists resident with activities of daily living (ADL's) and all personal care skills (bathing, dressing, grooming, toileting)
Makes appropriate observations about the resident’s condition in every interaction
Records and follows-up with changes in resident’s condition in a timely manner
Assists residents with laundry and housekeeping services as needed

What we offer

Medical, Dental and Vision
Early Wage Access (access to earned wages when needed!)
401k
10 days vacation & 1 hour Sick Leave earned for every 30 hours worked
Bereavement & Jury Duty Leave
6 Holidays
2 Float Holidays
Flexible Spending Accounts (Health and Dependent Care)
Meal Discounts
Tuition Assistance

Fulltime

Traffic Management CAD Technician

FM Conway is currently recruiting a Traffic Management CAD Technician to join ou...

Location

United Kingdom , Ipswich

Salary:

Not provided

360 Resourcing Solutions

Expiration Date

July 04, 2026

Requirements

Strong knowledge of Traffic Management operations
experience using CAD, BricsCAD and Cone 11 software
ability to read and translate blueprints and technical drawings
ability to work well under pressure, prioritise tasks effectively and have excellent attention to detail
M7 Lantra qualification is highly desirable, but not essential

Job Responsibility

Working within a team of Traffic Management development designers and Project Engineers to ensure that drawings are to a high and legal standard
Producing clear drawings, signage placement layouts and diversion route strategies
Developing safe and efficient traffic management plans for work sites and road network
Carrying out on site assessments as required
Designing sites in accordance with Chapter 8 TSM
Engaging with Project Teams & Engineers to respond effectively to working methods that require traffic Management designs that conform to a legal standard

What we offer

Career and professional development
23 days holiday plus bank holidays
Life assurance
Opportunities for internal and external training
Access to a wide range of shopping discounts through Rewarding Great People platform
Health and well-being benefits including 24-hour advice lines
Support from in-house mental health first aiders

Fulltime

Registered Nurse, CVOR

Baptist Downtown is hiring a Registered Nurse for our Cardiovascular Operating R...

Location

United States , Jacksonville

Salary:

Not provided

Baptist Health (Florida)

Expiration Date

Until further notice

Requirements

1-2 years Operating Room Nursing Experience Required
Basic Life Support (BLS) Required
Advanced Cardiac Life Support (ACLS) Required
Licensed Registered Nurse Required
Associate of Science, Nursing
Registered Nurse (RN) - State Nursing Boards
Driver's License - DMV
Basic Life Support (BLS) - AHA
Advanced Cardiac Life Support (ACLS) - AHA

Job Responsibility

Providing for patient needs as recognized through use of the nursing process
Supervision of care provided by supportive personnel and coordination of care provided by ancillary services
Including patients and significant others (SO)/families in developing an individualized plan of care
Education of patients/SO/families to their disease process and plan of care
Coordinating and preparing assigned operating room/case
Assessment of patient care needs and the anticipation of needs of the case
Circulating, scrubbing, assisting on Cardiothoracic and vascular procedures

Fulltime

Pediatric Occupational Therapist

Wolfson Children's Hospital Rehab Services is hiring a Pediatric Occupational Th...

Location

United States , Jacksonville

Salary:

Not provided

Baptist Health (Florida)

Expiration Date

Until further notice

Requirements

Bachelor's degree (or higher) in Occupational Therapy Required
Licensed Occupational Therapist from FL Department of Health Required
Basic Life Support (BLS) certification from the American Heart Association Required
Pediatric Occupational Therapy in the outpatient setting is strongly preferred

Job Responsibility

Evaluates and treats patients with developmental, neurological, orthopedic, and medical diagnoses
Extensive patient/family education
Works with multidisciplinary team care

What we offer

$1,000 Sign on Bonus

Nursery Manager

Join the Kindred Family – Lead, Inspire, and Make a Difference. Are you an exper...

Location

United Kingdom , Hauxton

Salary:

34000.00 - 36000.00 GBP / Year

360 Resourcing Solutions

Expiration Date

Until further notice

Requirements

Proven experience in leading and managing a team within early years
Strong written and verbal communication skills
Excellent organisational skills and attention to detail
Outstanding customer service and time management
Full and relevant Early Years Level 3 Childcare Qualification or higher
Sound knowledge of EYFS and OFSTED guidelines

Job Responsibility

Lead the Deputy Manager, Third in Charge, and Room Leaders to ensure high standards of Early Years care and education
Maintain an organised, safe, and stimulating nursery environment
Keep accurate records and ensure procedures are followed across the nursery
Build and maintain a reputation as the nursery of choice for children and staff
Model and monitor best practice in line with regulatory guidelines
Inspire and support your team, overseeing inductions, mentoring, and ongoing development
Ensure the nursery runs efficiently, meets KPIs, budgets, and targets, and is prepared for audits and inspections
Oversee the day-to-day operations of the nursery
Lead by example, modelling good practice and creating a shared vision
Supervise, support, and allocate tasks to your team

What we offer

Birthday Off
6 Fully Paid Sick Days
Cashback Healthcare Plan
Retail Discounts
Recognition & Reward Scheme
50% Childcare Discount
24/7 Virtual GP Access
24/7 Counselling Support
Discounted Gym Membership
Personal Financial Advisor Access

Fulltime

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