Manufacturing Systems Engineer Job at Amgen (Holly Springs)

Principal Manufacturing Systems Engineer - Amgen Dun Laoghaire Project Delivery Lead

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part...

Location

Ireland , Dun Laoghaire

Salary:

Not provided

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree in Engineering and 2 years of combined Information Systems and Manufacturing Process Automation experience
Master’s degree in Engineering and 4 years of combined Information Systems and Manufacturing Process Automation experience
Bachelor’s degree in Engineering and 6 years of combined Information Systems and Manufacturing Process Automation experience
Engineering, Information Systems, Computer and/or Software GMP-regulated industry background with experience leading projects and resources
8+ years of experience in manufacturing, including 5+ in Pharma/Biotech industry
5+ years of combined experience with Automation/ Process Control Systems (PCS), Manufacturing Execution System (MES) and/or laboratory systems or IS platforms
5+ years of experience with packaging and/or filling line systems
Strong communication, leadership, and teamwork skills
Innovative, technically minded, and problem-solving abilities
Effective verbal, and written communication, and facilitation skills in the English language

Job Responsibility

Lead the execution and successful delivery of varied portfolio of IS/Automation projects with appropriate portfolio planning, resource and risk management and financial management for the portfolio
Accountable for end-to-end Technology projects delivery from the business case creation up to qualification and go live into manufacturing production
Ability to anticipate, evaluate and resolve multiple, simultaneous project issues, delays, and problems by utilizing technical, project management, and business expertise
Performs cross system analysis, feasibility analysis, scope projects, prioritize deliverables, and recommend optimal solution
Manage multiple initiatives and priorities
Ability to translate strategic opportunities and emerging technology solutions into tangible pragmatic executable plans allied to the ability to apply corporate blueprint and standards using business drivers to local business needs and project requirements
Effectively manage relationships with Peers, IS service owners, business partners, enterprise IS service partners, and vendors
Communicates with multiple levels within the organization, highlighting issues and proposing solutions
Accountable to elicit and analyze needs identified by business stakeholders and convert them into functional design

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible

Fulltime

Manufacturing Systems Integration Engineer

We are seeking a skilled Manufacturing Systems Integration Engineer to design, i...

Location

United States , Santa Clara

Salary:

122040.00 - 135600.00 USD / Year

Archer Aviation

Expiration Date

Until further notice

Requirements

Bachelor's or advanced degree in Engineering, Computer Science, or related field
3 - 5 plus years of experience in manufacturing systems integration
3+ years experience with Ignition platform development and administration
2+ years experience with Siemens Teamcenter configuration and integration
2+ years experience with SAP S/4HANA, particularly PP/MM modules
Strong knowledge of industrial communication protocols (OPC-UA, Modbus, Ethernet/IP)
Experience with databases (SQL Server, Oracle, MySQL)
Programming skills in Python, Java, or ABAP
Experience in automotive, aviation, or discrete manufacturing preferred
Knowledge of MES/MOM systems and manufacturing processes

Job Responsibility

Design and implement integrated manufacturing systems that connect shop-floor operations to enterprise systems
Develop and maintain system architecture documentation, integration plans, and technical roadmaps
Lead cross-functional initiatives to integrate MES with business applications and enterprise data systems
Troubleshoot, optimize, and improve system interfaces, data pipelines, and communication protocols
Develop and maintain SCADA/HMI applications using Inductive Automation’s Ignition platform
Configure and manage Ignition modules, including Vision, Perspective, and SQL Bridge
Build real-time dashboards, reports, and data-visualization solutions for manufacturing operations
Implement OPC-UA connectivity and database integrations within the Ignition environment
Develop custom scripting and automation solutions using Python within Ignition
Configure and customize the Siemens Teamcenter PLM system to support manufacturing and production requirements

Fulltime

MES Application Owner - Systems Engineer

In this vital role you will have the outstanding opportunity to support the star...

Location

United States , Holly Springs

Salary:

147421.00 - 177467.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree
OR Master’s degree and 2 years of Information Systems, Engineering and/or Information technology experience
OR Bachelor’s degree and 4 years of Information Systems, Engineering and/or Information technology experience
OR Associate’s degree and 8 years of Information Systems, Engineering and/or Information technology experience
OR High school diploma/GED and 10 years of Information Systems, Engineering and/or Information technology experience

Job Responsibility

Own the ongoing creation and roadmap for the Business and Automation platform applications, including system administration, configuration, and maintenance (i.e., MES Korber PAS|X, Emerson Delta V, Rockwell, Siemens, OSISoft PI, VeevaVault, iWAREHOUSE, VirTECS, Autodesk BIM 360) preferably biotechnology, pharmaceutical, or related industry
Collaborate with business partners and other technology professionals to develop and deploy the latest, advanced technologies in support of product manufacturing optimization
Collaborate with the rest of the manufacturing network to incorporate lessons learned and share ongoing best practices and with the business partners to understand how automation can improve workflow and productivity
Manage and/or support the execution of a varied portfolio of DTI projects with appropriate portfolio planning, resource and risk management and financial management for the portfolio
Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines
Lead selected efforts to design, build, and develop rapid Proof-of-Concept (POC) automated solutions and services
Quickly and iteratively prove or disprove the concepts being considered
Synthesize requirements from end-users, application architects, and cybersecurity experts to develop the best automation solutions
Work closely with the business and DTI Manufacturing System Engineers to identify opportunities to stop inefficient practices, simplify business processes, and codify into automated solutions and platforms
Ensure all work is completed within GMP regulations

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible

Fulltime

Director of Engineering (Manufacturing)

We are seeking a skilled Director of Engineering (Manufacturing) to join our gro...

Location

United States , Gunnison

Salary:

Not provided

Robert Half

Expiration Date

Until further notice

Requirements

Bachelor’s degree in Engineering (Mechanical, Industrial, or Manufacturing preferred
Master’s preferred)
Over 10 years of experience building and leading engineering teams in a manufacturing environment
Strong Program Management skills in handling complex multi-stakeholder projects
Able to balance leadership with hands-on engineering problem-solving
Expertise in process optimization, lean manufacturing, and advanced manufacturing systems
Proven innovation and efficiency achievements within manufacturing
Exceptional interpersonal and communication skills, with the ability to collaborate effectively
Willingness to relocate to Gunnison, Utah and work onsite

Job Responsibility

Lead, mentor, and manage a Manufacturing Engineering team to foster collaboration and continuous improvement
Develop and implement engineering strategies aligned with business goals for manufacturing process efficiency
Recruit engineering talent and promote professional development to grow the team
Manage cross-functional programs, ensuring they meet timelines and budgets while minimizing risks
Provide hands-on engineering support for critical projects and process optimizations
Implement best practices to enhance production workflows and improve product quality
Integrate cutting-edge manufacturing technologies to boost operational effectiveness
Collaborate with design, operations, supply chain, and quality teams for seamless development
Manage department budgets, resource planning, and capital projects
Ensure engineering compliance with company policies, regulations, and safety standards

What we offer

medical
vision
dental
life and disability insurance
401(k) plan

Fulltime

Manufacturing Engineer

As a Manufacturing Engineer at 1X, you will be a hands‑on technical leader respo...

Location

United States , Hayward

Salary:

90000.00 - 165000.00 USD / Year

1X Technologies

Expiration Date

Until further notice

Requirements

Bachelor’s degree in Mechanical Engineering, Mechatronics, Manufacturing Engineering, or related field
Minimum of 2 years of experience in manufacturing engineering, especially involving precision mechanical or electromechanical assemblies
Experience with CAM programming, fixture/tooling design, precision machining of metals or composites
Strong understanding of design for manufacturability (DFM) and experience integrating electromechanical systems
Familiarity with measurement techniques and standards such as GD&T, tolerance stack analysis, CMM or other high‑precision inspection methods
Solid collaboration skills across engineering disciplines, supply chain, QA, and production teams
Experience producing robotic actuators, joints, or other motion control systems
Exposure to high‑mix, low‑volume environments with frequent design iteration
Knowledge or experience with lean manufacturing, Six Sigma, continuous improvement strategies
Proficiency with CAD tools, PLM/ERP systems, and manufacturing documentation

Job Responsibility

Develop and refine manufacturing processes for robotic mobility and control components such as actuators, drive units, precision components, motor housings, and skeletal structures
Oversee full manufacturing workflows including fixture design, CAM programming, selection of cutting tools, and inspection/validation methods
Deploy automation and lights‑out machining strategies to enable continuous production with minimal human intervention
Drive process improvements to reduce cycle time, increase first‑pass yield, and improve reliability of robot hardware
Collaborate with design engineering on part geometry, materials, and design changes to ensure manufacturability at every stage
Manage change releases and product design revisions into production, focusing on scalability and consistency
Act as technical liaison between design, machining, assembly, and quality teams for owned components
Support build technicians and operators, maintain work instructions and operating procedures in up‑to‑date state
Implement statistical process control (SPC) and quality monitoring practices, take ownership of part or part family quality metrics
Troubleshoot production issues such as tolerance stack‑ups, tool wear, misalignment, and assembly variability

What we offer

Health, dental, and vision insurance
401(k) with company match
Paid time off and holidays

Fulltime

Manufacturing Engineer

The successful candidate will play a crucial role in improving manufacturing pro...

Location

United States , Riverside

Salary:

Not provided

Robert Half

Expiration Date

Until further notice

Requirements

Minimum of 3 years of experience as a Manufacturing Engineer or in a similar role
Proficiency in Mechanical Assembly, Mechanical Design, and Mechanical Components
Experience with Mechanical Drawings and Mechanical Engineering
Familiarity with Mechanical Equipment and Mechanical Systems
Skilled in Welding and Welding Inspection
Knowledge of Semiconductor Fabrication and Lean Manufacturing
Experience in Manufacturing, Manufacturing Assembly, and Manufacturing Engineering
Understanding of Manufacturing Equipment and Manufacturing Practices
Familiarity with ASME Y14.5 and ISO Standards
Proven experience in Quality Control, Equipment Calibration, and Equipment Maintenance

Job Responsibility

Develop, implement and manage a comprehensive facility weld program in line with company standards
Optimize welding operations and drive manufacturing improvements to enhance productivity and safety
Oversee the site weld program, including WPS/PQR, Welder Certifications, and equipment automation programs
Provide technical support and troubleshooting for various welding processes such as MIG, TIG, and others
Collaborate with Quality Control to ensure welding processes adhere to industry standards and customer specifications
Lead the design, implementation, and improvement of manufacturing projects related to welding and fabrication
Train production staff on proper welding techniques, equipment operation, and best practices
Work closely with Sales Administration to understand and meet customer welding requirements
Create and maintain technical documentation, including work instructions, process sheets, and project reports
Recommend, procure, and oversee the maintenance of welding equipment and tools

What we offer

medical, vision, dental, and life and disability insurance
eligibility to enroll in company 401(k) plan

Fulltime

Lead Systems Engineer

Magdrive is developing the next generation of spacecraft propulsion. Our thruste...

Location

United Kingdom

Salary:

65000.00 - 75000.00 GBP / Year

Magdrive

Expiration Date

Until further notice

Requirements

5+ years’ experience in systems engineering and product delivery in aerospace/space (or other complex engineering domains), including 2+ years in a senior capacity
Skilled at defining and managing system requirements and interfaces
Proven ability to plan and manage system integration and testing
Strong problem-solving and trade-off decision-making skills
Effective communicator and collaborator across disciplines
Direct space domain experience (e.g. spacecraft, propulsion, or satellite systems)

Job Responsibility

Define, implement, and maintain the system architecture for flight hardware and ground support systems
Own system-level requirements, interface control documents (ICDs), verification plans, and risk register
Ensure full traceability from customer needs to subsystem specifications and test cases
Plan and oversee system integration across hardware, software, and test environments
Collaborate with technical teams to ensure systems are buildable, testable, and deliverable
Support Product/Program teams with flight-readiness reviews and customer delivery milestones
Design, implement, and maintain systems engineering tools and processes (e.g. MBSE, configuration control, gated reviews)
Codify organisational knowledge into scalable workflows
Work closely with Product, Program, and Engineering teams to align technical decisions with delivery goals
Act as a system-level technical interface with customers and external partners

What we offer

25 days annual leave + bank holidays, plus long-service awards (up to 30 days)
Private medical insurance
Flexible working hours
Remote working where possible
Financial support for home office setup

Fulltime

Senior Engineer, Weld Manufacturing

Being an Engineer at Baxter means you play a critical role in helping us achieve...

Location

United States , Batesville

Salary:

88000.00 - 121000.00 USD / Year

Baxter

Expiration Date

Until further notice

Requirements

Bachelor’s degree in Engineering required
Over 2 years of job-related experience in manufacturing and weld engineering
Experience with Lean Manufacturing disciplines
Ability to work to a high degree of accuracy in a broad range of tasks associated with production welding with limited supervision
Knowledge of design techniques, weld tooling, and weld processes involved in the production of precision technical plans, blueprints, drawings, and models
A strong mechanical and metallurgical background with a thorough knowledge of GMAW, GMAW-P, RSW, GTAW is preferred
Knowledge of welding processes, equipment and robotic applications
Ability to develop, lead and execute multiple projects, simultaneously and still meet desired results
Demonstrated leadership of capital / CI projects focused on meeting departmental goals
Identifying complex problems and reviewing related information to develop and evaluate options and implement solutions

Job Responsibility

Identify opportunities or implement changes to improve products or reduce costs using knowledge of fabrication processes, tooling and production equipment, weld processes, quality control standards, or product design, powder coating, materials and parts
Troubleshoot new or existing product problems involving designs, materials, or processes
Provide technical expertise or support related to manufacturing
Confer with engineers or other personnel to implement operating procedures, resolve system malfunctions, or provide technical information
Determine root causes of failures using statistical methods and recommend changes in designs, tolerances, or processing methods
Perform nonconforming material analysis and create NCM reports
Work with Quality Control on reducing the NCMRs
Plan and establish sequence of operations to fabricate, weld, paint, plate parts or products and to achieve maximum efficiency and utilization
Read and interpret blueprints, technical drawings, schematics, or computer-generated reports
Ability to design and set up weld robot cells for maximum efficiency

What we offer

Support for Parents
Continuing Education/ Professional Development
Employee Heath & Well-Being Benefits
Paid Time Off
2 Days a Year to Volunteer
medical and dental coverage
insurance coverage for basic life, accident, short-term and long-term disability, and business travel accident insurance
Employee Stock Purchase Plan (ESPP)
401(k) Retirement Savings Plan (RSP)
Flexible Spending Accounts

Fulltime

Manufacturing Systems Engineer

Amgen

Location:
United States , Holly Springs

Category:
IT - Administration

Contract Type:
Not provided

Salary:

Job Description:

Job Responsibility:

Requirements:

Nice to have:

Additional Information:

Job Posted:
March 21, 2026

Looking for more opportunities? Search for other job offers that match your skills and interests.

Similar Jobs for Manufacturing Systems Engineer

Principal Manufacturing Systems Engineer - Amgen Dun Laoghaire Project Delivery Lead