CrawlJobs Logo
Amgen Logo Amgen · IT - Administration

Manufacturing Systems Engineer

United States, Holly Springs 118497.00 - 134250.00 USD / Year · Job Posted March 21, 2026
Apply Position
Job Link Share

Job Description

In this vital role, you will be accountable for developing and continuously aligning the site manufacturing data ecosystem with rapidly changing business needs and Amgen Technology technical roadmaps. We are seeking candidates who possess expertise in business, and automation systems, information/data management and technical experience in database and data historian technologies and integration tools. You will support the design, implementation, operation, and continuous improvement of manufacturing automation and information systems across the site. You will partner closely with manufacturing, quality, engineering, cybersecurity, and enterprise platform teams to ensure systems are reliable, compliant, and aligned with Amgen technology roadmaps.

Job Responsibility

  • Support and/or lead the design, deployment, and lifecycle management of manufacturing automation and information systems: Delta V, FactoryTalk / Rockwell platforms, Building Automation Systems (BAS), ThinManager and mobile solutions, and Siemens Location tracking and/or related site services
  • Provide technical support to manufacturing operations, including troubleshooting, system performance improvements, and incident response
  • Participate in capital project execution, including requirements definition, design reviews, testing, validation, and startup support
  • Own or contribute to system roadmaps, lifecycle planning, and technical debt reduction
  • Collaborate with business partners to translate operational needs into functional and technical designs
  • Support manufacturing data integrations, historians, reporting, and analytics solutions
  • Ensure systems meet GMP, data integrity, cybersecurity, and validation requirements
  • Manage vendor relationships and coordinate work with internal platform and service owners
  • Support and/or lead Global Asset Lifecycle Management (GLAM) initiatives, including platform lifecycle planning, implementation, sustainment, and continuous improvement
  • Identify opportunities to simplify processes, eliminate inefficiencies, and automate manual workflows
  • Stay current with industry and technology trends and apply learnings pragmatically to site operations

Requirements

  • Master’s degree
  • OR Bachelor’s degree and 2 years of Information Systems, Engineering and/or Information Technology experience
  • OR Associate’s degree and 6 years of Information Systems, Engineering and/or Information Technology experience
  • OR High school diploma / GED and 8 years of Information Systems, Engineering and/or Information Technology experience

Nice to have

  • Experience supporting manufacturing automation and information systems in a regulated manufacturing environment, preferably within pharmaceutical or biotechnology industries
  • Hands-on experience with one or more automation or site systems platforms, such as DeltaV, Rockwell FactoryTalk, Building Automation Systems (BAS), ThinManager, Siemens location tracking, or related manufacturing platforms
  • Working knowledge of information systems infrastructure fundamentals, including Windows-based systems, virtualization, networking, storage, and Active Directory
  • Experience supporting or implementing manufacturing data integrations, historians, reporting, or analytics solutions (e.g., SQL, web services, data mapping)
  • Familiarity with GMP software development lifecycle, change control, validation practices, and regulated system support
  • Experience working with capital projects or complex system implementations, including design reviews, testing, and deployment
  • Ability to translate business and operational requirements into functional and technical solutions
  • Experience managing multiple priorities and contributing effectively in a fast-paced manufacturing environment
  • Strong communication skills and the ability to collaborate with both technical and non-technical stakeholders
  • Experience working with vendors and cross-functional teams to deliver and sustain technology solutions
  • Exposure to Agile or iterative delivery methodologies is a plus

What we offer

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
Amgen - All Job Offers

Looking for more opportunities?

Search for other job offers that match your skills and interests.

Suggested Tags: Frontend Developer Secretary Talent Manager Salesforce Administrator Data Analyst
Similar Jobs for

Manufacturing Systems Engineer

8 matching positions

Manufacturing Systems Engineer

Manage and support shopfloor applications within a manufacturing environment. Ev...
Location
Location
Singapore
Salary
Salary:
Not provided
amaris.com Logo
Amaris Consulting
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Experience in application management for shopfloor environments (4–6 years)
  • Strong understanding of shopfloor systems and workflows
  • Experience in user experience evaluation and process improvement
  • Hands-on experience in implementation and change management
  • Ability to analyze multiple solutions and provide structured recommendations
  • Exposure to digital transformation initiatives within manufacturing settings is a plus
  • English fluent
  • Other languages are a plus
  • You demonstrate strong stakeholder management and communication skills
Job Responsibility
Job Responsibility
  • Manage and support shopfloor applications within a manufacturing environment
  • Evaluate user experience and identify gaps, inefficiencies, or areas for improvement
  • Drive implementation of enhancements and digital solutions for shopfloor operations
  • Lead and support change management activities related to system or process improvements
  • Assess different technical solutions and provide recommendations based on business needs
  • Collaborate with cross-functional teams to ensure smooth integration across shopfloor systems
  • Continuously improve processes by enhancing system connectivity and digitalization across shopfloor workflows
What we offer
What we offer
  • Global Diversity: Be part of an international team of 110+ nationalities
  • Trust and Growth: 70% of our leaders starting at entry-level
  • Continuous Learning: internal Academy and over 250 training modules
  • Vibrant Culture: afterworks, networking events
  • Meaningful Impact: CSR initiatives, including the WeCare Together program
  • Fulltime
Read More
Arrow Right

Manufacturing Systems Engineer: Automation

Location
Location
United States , Holly Springs
Salary
Salary:
105362.60 - 142549.40 USD / Year
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • High School Diploma / GED and 8 years of Engineering experience OR Associate's Degree and 6 years of Engineering experience OR Bachelor's Degree and 2 years of Engineering experience OR Master's Degree
  • Degree in Electrical Engineering, Computer Science, Chemical Engineering, Biotech Engineering, or related field
  • Direct knowledge of Automation System design, experience in process control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automation such as media, harvest, bioreactors, solution prep, single use mixing vessels, chromatography, TFFL/TFFX, viral filtration, viral inactivation, UF/DF, depth filtration, drug substance fill, CIP/SIP, clean utilities, and integrating various OEM automation software
  • Experience in programming, installation, and lifecycle management of automation and field instrumentation technologies
  • Experience in programming, design, installation and lifecycle management of manufacturing process controls, and automation and field instrumentation technologies
  • Experience with Emerson DeltaV DCS system and ability to perform advanced troubleshooting, and system integration using OPC, Foundation Fieldbus, and Profibus technologies
  • Ability to interpret and apply GAMPs and GMPs, and familiarity with documentation in a highly regulated environment with requirements such as 21 CFR Part 11, ASTM 2500, S88 and S95
  • Self-directed team player able to work cross-functionally
  • Strong technical writing and communication skills
Job Responsibility
Job Responsibility
  • Develop and maintain the process control system on Emerson DeltaV distributed control system (DCS)
  • Collaborate with key stakeholders and end-users to understand and synthesize key process requirements, and to develop solutions using Amgen standard automation platform for process automation systems
  • Provide clear documentation for delivered solutions and processes
  • Support QA partners in performing computerized systems validation in a GxP environment
  • Perform Data Integrity Assessments (DIA) in accordance with the current Amgen and industry standards
  • Support process automation systems to ensure design aligns with Amgen specifications, incorporates the latest technology, and meets safety requirements
  • Support vendor FAT to ensure that control strategy and software code meet Amgen requirements
  • Develop and maintain engineering and maintenance documentation, and associated procedures for delivered solutions and processes
  • Support commissioning and qualification efforts including Automation Installation Verification/Automation Check Out (IV/ACO) in a fast-paced environment
  • Own and drive to completion Change Controls, CAPAs, and Deviations
What we offer
What we offer
  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible
  • Fulltime
Read More
Arrow Right

Manufacturing Systems Engineer: Automation

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part...
Location
Location
United States , Holly Springs
Salary
Salary:
105362.60 - 142549.40 USD / Year
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • High School Diploma / GED and 8 years of Engineering experience OR Associate’s Degree and 6 years of Engineering experience OR Bachelor’s Degree and 2 years of Engineering experience OR Master’s Degree
  • Degree in Electrical Engineering, Computer Science, Chemical Engineering, Biotech Engineering, or related field
  • Direct knowledge of Automation System design, experience in process control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automation such as media, harvest, bioreactors, solution prep, single use mixing vessels, chromatography, TFFL/TFFX, viral filtration, viral inactivation, UF/DF, depth filtration, drug substance fill, CIP/SIP, clean utilities, and integrating various OEM automation software
  • Experience in programming, installation, and lifecycle management of automation and field instrumentation technologies
  • Experience in programming, design, installation and lifecycle management of manufacturing process controls, and automation and field instrumentation technologies
  • Experience with Emerson DeltaV DCS system and ability to perform advanced troubleshooting, and system integration using OPC, Foundation Fieldbus, and Profibus technologies
  • Ability to interpret and apply GAMPs and GMPs, and familiarity with documentation in a highly regulated environment with requirements such as 21 CFR Part 11, ASTM 2500, S88 and S95
  • Self-directed team player able to work cross-functionally
  • Strong technical writing and communication skills
Job Responsibility
Job Responsibility
  • Develop and maintain the process control system on Emerson DeltaV distributed control system (DCS)
  • Collaborate with key stakeholders and end-users to understand and synthesize key process requirements, and to develop solutions using Amgen standard automation platform for process automation systems
  • Provide clear documentation for delivered solutions and processes
  • Support QA partners in performing computerized systems validation in a GxP environment
  • Perform Data Integrity Assessments (DIA) in accordance with the current Amgen and industry standards
  • Support process automation systems to ensure design aligns with Amgen specifications, incorporates the latest technology, and meets safety requirements
  • Support vendor FAT to ensure that control strategy and software code meet Amgen requirements
  • Develop and maintain engineering and maintenance documentation, and associated procedures for delivered solutions and processes
  • Support commissioning and qualification efforts including Automation Installation Verification/Automation Check Out (IV/ACO) in a fast-paced environment
  • Own and drive to completion Change Controls, CAPAs, and Deviations
What we offer
What we offer
  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible
  • Fulltime
Read More
Arrow Right

Senior Manufacturing Systems Engineer: Automation

HOW MIGHT YOU DEFY IMAGINATION? If you feel like you're part of something bigger...
Location
Location
United States , Holly Springs
Salary
Salary:
Not provided
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Basic Qualifications: High School Diploma / GED and 10 years of Engineering experience OR Associate's Degree and 8 years of Engineering experience OR Bachelor's Degree and 4 years of Engineering experience OR Master's Degree and 2 years of Engineering experience OR Doctorate Degree
  • Preferred Qualifications: Degree in Electrical Engineering, Computer Science, Chemical Engineering, Biotech Engineering, or related field
  • Direct knowledge of Automation System design, experience in process control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automation such as media, harvest, bioreactors, solution prep, single use mixing vessels, chromatography, TFFL/TFFX, viral filtration, viral inactivation, UF/DF, depth filtration, drug substance fill, CIP/SIP, clean utilities, and integrating various OEM automation software
  • Extensive understanding and background in programming, design, installation and lifecycle management of manufacturing process controls, automation and field instrumentation technologies
  • Experience with Emerson DeltaV DCS system, Process Control Network design including network segregation, virtual infrastructure design and implementation, and ability to perform advanced troubleshooting activities, system integration using OPC, Foundation Fieldbus, Profibus, and DeviceNet technologies. Experience with DeltaV Live is preferred
  • Ability to interpret and apply GAMPs and GMPs and familiarity with documentation in a highly regulated environment with requirements such as 21 CFR Part 11, ASTM 2500, S88, and S95
  • Experience in Capital Project Lifecycle Management: Conceptual Design, Scope and cost estimate development, business case development, detailed design, engineering and validation documentation and project execution
  • Demonstrated hands-on experience in developing process control strategies for New Product Introduction and New Technology Deployment for Drug Substance Plant Operations
  • Demonstrated experience with continuous improvements resulting in enhanced safety, system reliability, and productivity (e.g. cycle times, and reduced plant utilities usage etc.) related to Drug Substance Plant Operations
  • The ideal individual must be a self-directed team player ready to mentor and develop engineering staff and embrace a team-based culture that relies on collaboration for effective decision-making
Job Responsibility
Job Responsibility
  • Develop and maintain the process control system on Emerson DeltaV distributed control system (DCS)
  • Work with process subject matter experts (SMEs) to understand key process requirements and transform them into digital automated solutions
  • Collaborate with business partners to understand how automation can improve workflow and productivity
  • Synthesize requirements from clients, customers or end-users to develop the best automation solutions
  • Provide clear documentation for delivered solutions and processes
  • work closely with QA partners while supporting computerized systems validation processes in a GxP environment
  • Maintain Data Integrity Assessments with the current Amgen and Industry standards
  • Build the business processes to support the project scope in alignment with project timelines
  • Develop detailed specification and engineering policies and procedures that affect multiple organizational units
  • Support commissioning and qualification efforts including Automation Installation Verification/Automation Check Out (IV/ACO) in a fast-paced environment
What we offer
What we offer
  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible
  • Fulltime
Read More
Arrow Right

Senior Manufacturing Systems Engineer: Automation (Wednesday - Saturday Shift)

Be part of Amgen's newest and most advanced drug substance manufacturing plant. ...
Location
Location
United States , Holly Springs
Salary
Salary:
136906.95 - 185227.05 USD / Year
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • High School Diploma / GED and10years of Engineering experience OR Associate's Degreeand8years of Engineering experience OR Bachelor's Degree and4years of Engineering experience OR Master'sDegree and2years of Engineering experience OR DoctorateDegree
Job Responsibility
Job Responsibility
  • Develop and maintain the process control system on Emerson DeltaV distributed control system (DCS)
  • Work with process subject matter experts (SMEs) to understand key process requirements and transform them into digital automated solutions
  • Collaborate with business partners to understand how automation can improve workflow and productivity
  • Synthesize requirements from clients, customers or end-users to develop the best automation solutions
  • Provide clear documentation for delivered solutions and processes
  • work closely with QA partners while supporting computerized systems validation processes in a GxP environment
  • Maintain Data Integrity Assessments with the current Amgen and Industry standards
  • Build the business processes to support the project scope in alignment with project timelines
  • Develop detailed specification and engineering policies and procedures that affect multiple organizational units
  • Support commissioning and qualification efforts including Automation Installation Verification/Automation Check Out (IV/ACO) in a fast-paced environment
What we offer
What we offer
  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible
  • Fulltime
Read More
Arrow Right

Principal Manufacturing Systems Engineer

At Amgen, if you feel like you’re part of something bigger, it’s because you are...
Location
Location
United States , Thousand Oaks
Salary
Salary:
Not provided
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Doctorate degree and 2 years of Manufacturing automation/Information systems leadership experience
  • OR Master’s degree and 4 years of Manufacturing automation/Information systems leadership experience
  • OR Bachelor’s degree and 6 years of Manufacturing automation/Information systems leadership experience
  • OR Associate’s degree and 10 years of Manufacturing automation/Information systems leadership experience
  • OR High school diploma / GED and 12 years of Manufacturing automation/Information systems leadership experience
Job Responsibility
Job Responsibility
  • Lead large capital project and product teams by fostering Agile delivery while operating within GMP manufacturing environments
  • Partner with site and global stakeholders to prioritize demand, manage backlogs, and balance local needs with global strategy
  • Accountable for financials, resource planning, vendor performance, and delivery against scope, schedule, and quality targets
  • Drive global standards, templates, and best practices for large operations technology project and product design, deployment, lifecycle management, and support
  • Ensure solution delivery meets GMP compliance, data integrity, electronic batch records, and regulatory inspection readiness requirements
  • Lead cross-functional collaboration between site and corporate Operations, Quality, IT, OT, Automation, Platform Owners, and external system integrators
  • Own the global operations technology roadmap, including upgrades, standardization, harmonization, and site deployments
  • Mentor and coach junior project managers or Scrum Masters
  • Present status updates and progress to senior leadership at various governance meetings
What we offer
What we offer
  • Health and welfare plans for staff and eligible dependents
  • Financial plans with opportunities to save towards retirement or other goals
  • Work/life balance
  • Career development opportunities
  • Retirement and Savings Plan with generous company contributions
  • Group medical, dental and vision coverage
  • Life and disability insurance
  • Flexible spending accounts
  • Discretionary annual bonus program
  • Stock-based long-term incentives
  • Fulltime
Read More
Arrow Right

Associate Manufacturing Systems Engineer

In this vital role, you will be part of Amgen's newest and most sophisticated fi...
Location
Location
United States , New Albany
Salary
Salary:
96918.00 - 105697.00 USD / Year
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s degree
  • OR Associate’s degree and 4 years of Information Systems, Business Analysis, or related experience
  • OR High school diploma / GED and 6 years of Information Systems, Business Analysis, or related experience
  • Strong analytical and problem-solving skills
  • Clear verbal and written communication skills
  • Ability to work effectively in cross-functional and virtual teams
  • High level of initiative, curiosity, and eagerness to learn
  • Ability to manage multiple priorities in a fast-paced environment
  • Team-oriented mindset with a focus on collaboration and shared success
Job Responsibility
Job Responsibility
  • Own and support key manufacturing and digital systems within the Amgen Ohio operations and technology portfolio
  • Perform troubleshooting, maintenance, and performance monitoring of manufacturing systems
  • Collaborate with delivery, platform, and architecture teams to ensure solutions align with approved standards and guidelines
  • Support projects and initiatives including system upgrades, enhancements, and new technology introductions
  • Create process flows and diagrams to help visualize current-state and future-state processes and identify improvement opportunities
  • Work with business partners to understand how automation and digital solutions can improve workflow, data visibility, and productivity
  • Assist in gathering, documenting, and validating business and system requirements from end users and stakeholders
  • Support the creation and execution of test cases, test plans, and validation documentation to ensure systems meet business and regulatory requirements
  • Develop and maintain documentation such as SOPs, user guides, process maps, functional/design documents, and operational diagrams
  • Learn and apply Industry 4.0 concepts and manufacturing data integrations under the guidance of senior team members
What we offer
What we offer
  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible
  • Fulltime
Read More
Arrow Right

Senior Manufacturing Systems Engineer: Automation

Be part of Amgen's newest and most advanced drug substance manufacturing plant. ...
Location
Location
United States , Holly Springs
Salary
Salary:
147421.00 - 177467.00 USD / Year
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • High School Diploma / GED and 10 years of Engineering experience
  • Associate’s Degree and 8 years of Engineering experience
  • Bachelor’s Degree and 4 years of Engineering experience
  • Master’s Degree and 2 years of Engineering experience
  • Doctorate Degree
  • Degree in Electrical Engineering, Computer Science, Chemical Engineering, Biotech Engineering, or related field
  • Direct knowledge of Automation System design, experience in process control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automation
  • Extensive understanding and background in programming, design, installation and lifecycle management of manufacturing process controls, automation and field instrumentation technologies
  • Experience with Emerson DeltaV DCS system, Process Control Network design including network segregation, virtual infrastructure design and implementation, and ability to perform sophisticated troubleshooting activities, system integration using OPC, Foundation Fieldbus, Profibus, and DeviceNet technologies
  • Ability to interpret and apply GAMPs and GMPs and familiarity with documentation in a highly regulated environment with requirements such as 21 CFR Part 11, ASTM 2500, S88, and S95
Job Responsibility
Job Responsibility
  • Provide automation technical leadership to a group of automation engineers
  • Work hand in hand with the capital project team to deliver robust process automation systems to operate the new plant
  • Develop and maintain the process control system on Emerson DeltaV distributed control system (DCS)
  • Work with process subject matter experts (SMEs) to understand key process requirements and transform them into digital automated solutions
  • Collaborate with business partners to understand how automation can improve workflow and productivity
  • Synthesize requirements from clients, customers or end-users to develop the best automation solutions
  • Provide clear documentation for delivered solutions and processes
  • work closely with QA partners while supporting computerized systems validation processes in a GxP environment
  • Maintain Data Integrity Assessments with the current Amgen and Industry standards
  • Build the business processes to support the project scope in alignment with project timelines
What we offer
What we offer
  • Competitive and comprehensive Total Rewards Plans that are aligned with local industry standards
  • Fulltime
Read More
Arrow Right