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Manufacturing Manager

United States, Thousand Oaks Employment contract 106148.00 - 143612.00 USD / Year · Job Posted June 09, 2026
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Job Description

The Amgen Thousand Oaks, Building 20 Drug Product Manufacturing facility directly supports Amgen’s pipeline of clinical drug product supply to patients across the globe. The Manager Manufacturing – Drug Product role offers the opportunity to collaborate with multiple functions within the Thousand Oaks site on a routine basis in a dynamic environment (Quality Assurance, Quality Control, Engineering, Facilities, Maintenance, Process Development, Process Engineering, Regulatory Compliance, etc.) while developing a deep understanding of the manufacturing operations and planning activities within the facility. The Manager Manufacturing is responsible for developing a team of expert manufacturing associates and technicians within Drug Product operations, while championing a safe and compliant production environment through structured on-floor presence. In this position, the manager will ensure production areas and procedures remain in compliance with current Good Manufacturing Practices, set and measure team performance/goals, chip in to production scheduling decisions, and work cross-functionally to close nonconformance investigations and introduce new product skus.

Job Responsibility

  • Staff selection, training, oversight, performance, and development
  • Schedule adherence for tasks including, but not limited to manufacturing, qualification, and maintenance activities
  • Participating as a role model in Lean culture and continuous improvement programs with responsibility to translate onto the manufacturing floor
  • Elevating critical and impactful events to senior management and make real time processing decisions
  • Ensuring standard operating procedures are accurate for performing unit operations, batch record review is completed accurately meeting disposition timelines, and non-conformances are initiated & closed with right the first time documentation
  • Using appropriate systems for job duties (SAP, QMTS, and LIMS etc.) and identifies and implements process and safety improvements
  • Communicate production floor and project work at different levels of management
  • Interacting with business partners and internal/external audit teams including regulatory agencies as required
  • Working with business partners to assist with scheduling of maintenance tasks, engineering evaluations, and quality investigations
  • Supporting the introduction of new products and technologies into the facility
  • Troubleshoot and perform initial assessment of events that have the potential to impact area safety and product quality
  • Assessing departmental utilization to complete both near-term schedule and long-term strategy

Requirements

  • Doctorate degree OR Master’s degree and 3 years of drug product manufacturing or operations experience OR Bachelor’s degree and 5 years of drug product manufacturing or operations experience OR Associate’s degree and 10 years of drug product manufacturing or operations experience OR High school diploma / GED and 12 years of drug product manufacturing or operations experience
  • experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources

Nice to have

  • At least 10 years of biopharmaceutical experience, with 3 years of leadership experience directly within drug product manufacturing that includes aseptic and sterile filling environments
  • Bachelor's or Master's degree in Microbiology, Life Sciences, Business or a related field
  • Strong understanding of lean concepts and application within a regulated manufacturing environment
  • Effective at working in fast-paced environments, specifically in a leadership capacity to facilitate objective decision making

What we offer

  • health and welfare plans for staff and eligible dependents
  • financial plans with opportunities to save towards retirement or other goals
  • work/life balance
  • career development opportunities
  • Retirement and Savings Plan with generous company contributions
  • group medical, dental and vision coverage
  • life and disability insurance
  • flexible spending accounts
  • discretionary annual bonus program
  • stock-based long-term incentives
  • award-winning time-off plans
  • flexible work models where possible

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