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Helpcare AI Logo Helpcare AI · IT - Software Development

Lead Software Engineer, Platform

United States · Job Posted January 26, 2026
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Job Description

PostEra is building a modern, 21st-century biopharma. We use Proton, our AI platform for medicinal chemistry, to accelerate the discovery of new medicines for patients. In this role, you will be helping PostEra deliver on its mission of getting therapies to patients by shaping systems design decisions around our drug discovery platform, Proton. Design focus areas include things like data architecture, microservice design, and patterns for running async compute-heavy ML jobs.

Job Responsibility

  • Lead the architectural design and contribute to the development of scalable web applications and microservices
  • Using cloud providers (ideally AWS), container orchestration frameworks, and IaC best practices
  • Working with teams who ship products using web-dev stacks composed of Python, modern frontend frameworks, and relational databases like PostgreSQL
  • Play a pivotal role in mentoring engineers, promoting a culture of cross-team collaboration and continuous learning
  • Be instrumental in facilitating knowledge sharing sessions, code reviews, and defining team-wide technical standards
  • Nurture the technical growth of our team members, while directly managing a small team of direct reports, with the possibility of growing into a larger people leadership role

Requirements

  • 5+ years of experience and a bachelor's degree (or more advanced education) to succeed in this role
  • Experience in systems design and backend web development
  • An interest in technical mentorship and management
  • US citizen/visa only

Nice to have

  • Expertise in a python based backend web framework (we use Django, for example)
  • Experience integrating ML systems into production services/software
  • Familiarity with container orchestration or workflow systems (like: Kubernetes, Kubeflow, Argo, Airflow)
  • Have some familiarity with data pipelines
  • Experience with designing agentic workflows/context engineering
  • Past roles with technical mentorship focus or people management responsibilities
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