Lead Scientist, Protein Engineering Job at Life Science Talent (Søborg)

New

Director senior director antibody discovery

BigHat is seeking an exceptional and highly experienced individual for a positio...

Location

United States , San Mateo

Salary:

230000.00 - 270000.00 USD / Year

BigHat Biosciences

Expiration Date

Until further notice

Requirements

Ph.D. in molecular biology, biochemistry, protein engineering, or related discipline with 12+ years of experience in antibody discovery and engineering within academia, biotechnology, or pharmaceutical industries
8+ years of managerial experience leading scientific teams
Strong expertise with protein display systems such as yeast, phage, mammalian, or mRNA display
Demonstrated experience with antibody library design, construction, screening, and selection analysis
Deep understanding of antibody structure-function relationships and mechanisms of antigen recognition
Experience integrating antibody discovery workflows with downstream characterization and developability assessment, including functional screening and biophysical evaluation of antibody candidates
Familiarity with computational or ML-enabled approaches to protein design and optimization
Experience advancing biologics from early discovery through lead optimization stages
Knowledge of diverse antibody modalities including multispecific antibodies, antibody fragments, and other advanced formats
Strong leadership skills with experience building and mentoring scientific teams

Job Responsibility

Lead BigHat’s antibody discovery and display functions, setting the scientific, technical, and strategic direction
Oversee the routine execution of display-based selection campaigns to enhance and diversify affinity, developability, and function across diverse antibody formats and antigen types in support of BigHat and BigHat-partnered therapeutic programs
Manage and mentor a team of scientists responsible for antibody library design, generation, screening, selection, and early optimization
Shape and expand BigHat’s antibody discovery technologies and capabilities, including new display and selection methods, library design strategies, and technical approaches that leverage and enhance the company’s integrated experimental and computational platform
Provide scientific leadership across discovery and early optimization efforts, ensuring antibodies emerging from selections possess strong functional and developability characteristics
Work closely with leaders in Protein Sciences, Data Science/Machine Learning, Engineering, and Platform groups to ensure seamless progression from discovery through characterization and optimization
Collaborate with biology and therapeutic research leads to ensure display outputs align with and advance program objectives
Foster a collaborative and high-performance culture within the discovery organization

What we offer

Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
Dental, and vision coverage through Guardian
Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
401(k) with company match
DTO, two weeks of company-wide shutdown, and 12 company holidays
Paid parental leave
bonus
options

Fulltime

Antibody Engineering & Computational Design

We are looking for exceptional antibody engineers and computational protein desi...

Location

United States , San Francisco

Salary:

Not provided

Chai Discovery

Expiration Date

Until further notice

Requirements

PhD or equivalent experience in the field—Antibody Engineering, Computational Biology, Protein Sciences
Hands-on experience with design and characterization of antibody-based biologics
Proficient in molecular-biology workflows, binding and developability assays, inspecting structures in PyMOL or similar tools
Track record of strong communication, collaboration and execution

Job Responsibility

Help evaluate, expand and apply the capabilities of our de novo antibody design models
Probe the design space for novel targets and formats
Validate in silico solutions for function in the lab
Distill empirical rules from the results
Execute experimental programs at scale that guide, train and evaluate next generation models
Partner with scientists from the world's leading pharma companies to push their discovery programs into new territory

What we offer

Highly competitive compensation

Fulltime

Research Scientist

As an AI Research Scientist, you will conduct groundbreaking research on computa...

Location

United States , San Francisco

Salary:

Not provided

Chai Discovery

Expiration Date

Until further notice

Requirements

Ph.D. or equivalent research experience in Machine Learning, Computational Biology, Bioinformatics, Computational Chemistry, or a related field
Strong publication or project record in top ML or life-science venues (NeurIPS, ICML, Nature Methods, PLoS CB, J. Chem. Inf. Model., etc.)
Proficient in Python and deep-learning frameworks
Experience training and evaluating large models on protein, antibody, or small-molecule data, or demonstrably transferable ML expertise
Able to translate open-ended scientific questions into tractable modeling experiments
Skilled at wrangling large biological or chemical datasets, computing meaningful metrics, and visualizing results for diverse audiences
Enjoy working in cross-functional teams, aligning with wet-lab scientists, software engineers, and product leads
Clear communicator who can distill complex findings into next-step recommendations for both technical and non-technical stakeholders
Curious, ambitious, and comfortable iterating quickly on v0 ideas
Motivated by turning breakthrough research into real-world therapeutic impact

Job Responsibility

Conduct groundbreaking research on computational modeling for biological applications
Push the frontier of AI drug design

What we offer

Frontier technology: work on the technologies that promises to fundamentally change how new therapeutics are created
World-class people: work with world-renowned leaders in the AI x Biology ecosystem
Velocity and ownership: we move incredibly fast and liberally distribute ownership, which means continuous learning and career growth opportunities are guaranteed
Strong culture and mission: we foster a supportive culture that is mission-driven and high-energy
Highly competitive compensation: we attract the best talent and compensate them accordingly

Fulltime

New

Senior Director – BioIntelligence

The AI & Data for Engineered Biologics (AIDE) organization at Amgen is seeking a...

Location

United States , Thousand Oaks

Salary:

239775.00 - 295217.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree in Computational Biology, Machine Learning, Bioinformatics, Computer Science, Biophysics, or related field and 5 years of experience applying machine learning or computational modeling to biological systems
OR Master’s degree in Computational Biology, Machine Learning, Bioinformatics, Computer Science, Biophysics, or related field and 9 years of experience applying machine learning or computational modeling to biological systems
OR Bachelor’s degree in Computational Biology, Machine Learning, Bioinformatics, Computer Science, Biophysics, or related field and 11 years of experience applying machine learning or computational modeling to biological systems
At least 5 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources

Job Responsibility

Lead the BioIntelligence Team within our Large Molecule Discovery organization, defining strategy and priorities for AI-driven biologics modeling
Develop and execute a roadmap for machine learning and AI approaches that accelerate engineered biologics discovery
Align BioIntelligence capabilities with broader Research and Large Molecule Discovery priorities
Oversee development of predictive models for key biologics properties, including developability, stability, manufacturability, and immunogenicity
Advance modeling approaches using modern AI techniques such as: protein language models
generative modeling and inverse folding
representation learning
active learning and Bayesian optimization
Guide the use of multimodal biological datasets including sequence, structure, and experimental assay data
Lead development of production-quality research software and deployable ML models used across discovery teams

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible

Fulltime

Principal Scientist/Senior Scientist Nucleic Acid Delivery

We are looking for a passionate and innovative Scientist in the field of Nucleic...

Location

United States , Cambridge

Salary:

Not provided

Evonik Industries

Expiration Date

Until further notice

Requirements

Ph.D. and 4+ or 8+ years (M.Sc.) of relevant industry experience in LNP development and drug delivery with a strong background in nucleic acid therapeutics and education in a related discipline (Pharmaceutical Sciences, Biomedical Engineering, Biochemistry, etc.)
Strong theoretical and practical knowledge of lipid-based and polymer-based delivery systems, manufacturing technologies, and hands-on experience in nanoparticle characterization techniques (e.g., DLS, zeta potential, ribogreen, pKa, chromatography)
Knowledge of formulation downstream purification methods such as ultrafiltration and tangential flow filtration (TFF)
Knowledge of lipid chemistry and bioconjugation techniques
Knowledge of cell-based assays for evaluating the performance and mechanism of action of novel delivery systems
Familiarity with gel electrophoresis for nucleic acid and protein characterization
Ability to work in a biosafety level 2 environment
Experience in setting up and operating high-throughput screening protocols for delivery formulations
Knowledge of formulation or assay automation, including lab automation equipment setup, programming, and the application of machine learning approaches
Proven ability to independently interpret experimental data, troubleshoot technical challenges, and develop innovative solutions

Job Responsibility

Lead the design, development, and characterization of novel non-viral vector platforms for targeted delivery of nucleic acid-based therapeutics, including lipid nanoparticles and alternative gene delivery systems
Establish relevant in vitro assays and conduct high-throughput in vitro experiments to evaluate the efficacy and safety of developed formulations in traditional and advanced cell culture models
Engage with customers to understand their needs and execute feasibility projects
Collaborate with cross-functional teams to define project scopes, timelines, and deliverables based on market needs and internal capabilities, while taking a leadership role in project management
Identify and evaluate emerging technologies in nucleic acid delivery, contributing to the strategic direction of research initiatives and leading efforts to integrate these technologies into ongoing projects
Document research findings and present results to internal stakeholders and at scientific conferences, fostering a culture of innovation within the team and promoting the dissemination of knowledge
Mentor junior scientists, technicians and students, providing guidance and support in their professional development, and leading training sessions to enhance team capabilities
Engage with external partners in academia and industry to enhance collaborative efforts and knowledge exchange, including leading initiatives to establish new partnerships and collaborations
Stay abreast of industry trends and scientific advancements, integrating relevant findings into ongoing research and development efforts

What we offer

performance-based remuneration
occupational health benefits
hybrid and flexible working environments with #SmartWork
attractive career paths
high-quality development programs

Fulltime

New

Senior Analytical Scientist/ Investigator

We are looking to fill a new Senior Analytical Scientist/ Investigator position ...

Location

Singapore , Tuas

Salary:

Not provided

GSK

Expiration Date

Until further notice

Requirements

At least a degree in Pharmacy, Chemistry, Pharmaceutical Sciences, Biochemistry/ Biotechnology, Biomedical Engineering or equivalent
Extensive hands-on experience in an analytical environment, preferably in the pharmaceutical industry with understanding of GMP and GLP requirements or equivalent
Prior experience in analytical technologies for the analysis and characterization of small molecules, biologics or vaccines is preferred
Hands-on experience, skilled in the execution, optimization and trouble-shooting in one or more of the following analytical techniques is preferred: Chromatographic techniques (2D-ULPC, HPLC-CAD, SEC-MALS), real time multi-angle light scattering (RT-MALS), analysis of biomolecular interactions by bio-layer interferometry (BLI), fluorescence-based assays, spectrophotometric techniques and colorimetric assays, dynamic light scattering (DLS), protein content by Lowry assay, nucleic acid content determination by fluorometry
Basic knowledge of drug substance and/ or drug product manufacturing processes for vaccines products is preferred
Enjoy working in a laboratory environment and thrive in activities and tasks related to analytical method development, troubleshooting, optimization, problem solving and root cause analysis under time pressure, to meet business needs and project implementation timelines
Excellent inter-personal communication skills, proactive with leadership skills, data-driven decision making, project management and stakeholder management skills with the experience and ability to work in cross-functional and global teams (across R&D, quality and global analytical hubs)
Possess a continuous improvement mindset and be able to lead improvement initiatives

Job Responsibility

Analytical Leadership and Innovation: Spearhead the full spectrum of analytical activities, including setting up advanced equipment, analytical method technology transfer and optimization, non-routine characterization and comparability assessments of drug substances and intermediates to support development and commercial manufacture of new vaccines products
Data-Driven Insights and Recommendations: Pro-actively generate and interpret comparability data of drug substances/ intermediates as part of material and process changes/ improvements to drive high impact, data-driven recommendations for the development and optimization of manufacturing processes
Problem-Solving and Root Cause Analysis: Lead laboratory investigations and trouble-shooting related to analytical equipment, methods and out-of-trend results, ensuring timely resolution with effective corrective and preventive actions
Development of Robust Analytical Strategies: Review and improve analytical methods, procedures and standards in accordance with pharmacopoeia requirements and in-house analytical technical standards
Analytical Equipment Stewardship: Qualification and lifecycle maintenance (including preventive maintenance/ calibration and performance verification checks) of equipment to appropriate analytical standards
Lifecycle Data Management: Ensure thorough, complete and accurate documentation of all laboratory procedures and data
Champion for Laboratory Safety and Sustainability: Lead/ support environmental health, safety and sustainability activities for the laboratory
Mentorship and Development: Supervise, train and develop interns and junior scientists

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

New

Pharmacy Technician

We’re building a world of health around every individual — shaping a more connec...

Location

United States , Albemarle

Salary:

16.50 - 25.00 USD / Hour

CVS Health

Expiration Date

May 25, 2026

Requirements

Must comply with any state board of pharmacy requirements or laws governing the practice of pharmacy, which includes but is not limited to, age, education, and licensure/certification
If the state board of pharmacy does not address or mandate a minimum age requirement, must be at least 16 years of age
If the state board of pharmacy does not address or mandate a minimum educational requirement, must have a high school diploma or equivalent, or be actively enrolled in high school or high school equivalency program
Regular and predictable attendance, including nights and weekends
Ability to complete required training within designated timeframe
Attention and Focus: Ability to concentrate on a task over a period of time
Ability to pivot quickly from one task to another to meet patient and business needs
Ability to confirm prescription information and label accuracy, ensuring patient safety
Customer Service and Team Orientation: Actively look for ways to help people, and do so in a friendly manner
Notice and understand patients’ reactions, and respond appropriately

Job Responsibility

Living our purpose by following all company SOPs at each workstation to help our Pharmacists manage and improve patient health
Following pharmacy workflow procedures at each pharmacy workstation (i.e., production, pick-up, drive-thru, and drop-off) for safe and accurate prescription fulfillment
Contributing to positive patient experiences by showing empathy and genuine care: creating heartfelt and personalized moments while serving patients at pick-up, drive-thru, and over the phone
keeping patients healthy by offering immunizations and other services at the register and over the phone
and demonstrating compassionate care by solving or escalating patient problems
Completing basic inventory activities, as permitted by law, and as directed by the pharmacy leadership team, such as accurately putting away medication deliveries and completing cycle counts, returns-to-stocks, waiting bin inventories, etc.
Contributing to a high-performing team, embracing a growth mindset, and being receptive to feedback
actively seeking opportunities to expand clinical and technical knowledge needed to better assist patients
Remaining flexible for both scheduling and business needs, while contributing to a safe, inclusive, and engaging team dynamic
voluntarily traveling to stores in the market to work shifts as needed by the business

What we offer

Affordable medical plan options
a 401(k) plan (including matching company contributions)
an employee stock purchase plan
No-cost programs for all colleagues including wellness screenings, tobacco cessation and weight management programs, confidential counseling and financial coaching
Benefit solutions that address the different needs and preferences of our colleagues including paid time off, flexible work schedules, family leave, dependent care resources, colleague assistance programs, tuition assistance, retiree medical access and many other benefits depending on eligibility

Fulltime

New

Senior Lead Accountant

We are looking for a Senior Lead Accountant for our Corporate Accounting team. Y...

Location

United States , Redlands

Salary:

76960.00 - 127920.00 USD / Year

Esri

Expiration Date

Until further notice

Requirements

8+ years of prior experience in public accounting or a similar position
Strong knowledge of Generally Accepted Accounting Principles (GAAP) and financial consolidation
Demonstrated ability to prepare and analyze financial statements
Strong analytical, problem-solving and organizational skills, with the ability to prioritize and manage multiple tasks and deadlines
Excellent verbal and written communication skills, with the ability to communicate complex accounting issues to various levels of the organization
Advanced Microsoft Excel skills, including XLOOKUPS and pivot tables
Visa sponsorship is not available for this posting. Applicants must be authorized to work for any employer in the US
Bachelor's degree in accounting, or in a related field with an Accounting Certificate or qualification, which meets the California CPA eligibility

Job Responsibility

Support the month and year-end close process for all domestic entities, ensuring accuracy and completeness of financial statements and compliance with local GAAP, laws, and regulations
Conduct monthly close functions such as reviewing and posting general ledger entries, reviewing monthly reconciliations, and supporting necessary management reporting analysis
Ensure quality control over financial transactions, financial reporting, and monthly allocations
Develop and maintain accounting policies and procedures and ensure adherence to best practices
Support and implement complex accounting issues and transactions and provide technical guidance and recommendations
Interact closely with FP&A and effectively communicate transactions that will impact results and forecasts including short range outlooks, annual and long-range plan development processes
Support operational areas that have a direct impact on domestic accounting activities such as AP, Assets, and other accounting transactional functions
Manage, mentor, and develop a team of accounting professionals, providing feedback, coaching and career development opportunities
Drive process improvements and automation to enhance efficiency and accuracy of the accounting function

What we offer

medical, dental, vision, basic and supplemental life insurance for employees (and their families), 401(k) and profit-sharing programs, minimum accrual of 80 hours of vacation leave, twelve paid holidays throughout the calendar year, and opportunities for personal and professional growth
Relocation Assistance Program

Fulltime

Lead Scientist, Protein Engineering

Life Science Talent

Location:
Denmark , Søborg

Category:
Research and Development

Contract Type:
Not provided

Salary:

Job Description:

Job Responsibility:

Requirements:

Nice to have:

Additional Information:

Job Posted:
March 24, 2026

Expiration:
April 10, 2026

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