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Lead Clinical Laboratory Scientist (CLS), Oncology

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BillionToOne

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Location:
United States , Menlo Park

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Category:
Health and Beauty

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Contract Type:
Not provided

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Salary:

228788.00 USD / Year ▼
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Job Description:

Join a team of brilliant, passionate innovators who wake up every day determined to transform healthcare. At BillionToOne, we've built something extraordinary—a culture where transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: talented scientists, engineers, sales professionals, and visionaries united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion—every innovation you contribute helps remove fear of unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong.

Job Responsibility:

  • Lead clinical laboratory daily supervision in alignment with company values and mission
  • Hold General Supervisor delegation and responsibilities including oversight and support of day-to-day operations, scheduling, and troubleshooting
  • Manage CLIA direct reports including licensed and/or unlicensed staff (CLS, Clinical Laboratory Assistants)
  • Contribute to continuous process improvement projects including tech transfer, troubleshooting, training, and validations
  • Perform clinical laboratory assays to provide data for diagnosis, treatment, and prevention of disease
  • Perform quality control studies to ensure the accuracy of clinical data
  • Verify instrument performance by checking and calibrating specific lab instruments and documents data

Requirements:

  • Bachelor's degree in the chemical, physical or biological sciences
  • Minimum of 4 years of CLS experience in a clinical setting (molecular and/or high-complexity laboratory experience preferred)
  • A current California Clinical Laboratory Scientist License that meets requirements for Testing Personnel under CLIA regulations (42 CFR, part 493) (ASCP, CGMBS or generalist license is required)
  • Hands-on training and experience with manual molecular biology protocols, including DNA extraction, PCR, and automated liquid handlers
  • Advanced knowledge of Google Docs, Word, Excel, basic statistics and familiarity with LIMS systems and Next-Generation Sequencing
  • Strong attention to detail and ability to work flexibly and well under given timeframes.
  • Self-starter and dynamic team player with excellent verbal and written skills.

Nice to have:

  • Previous CLIA General Supervisor experience
  • Start-up experience
  • Knowledge of medical genetics
  • Experience in a cell-free DNA setting
What we offer:
  • Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
  • Open, transparent culture that includes weekly Town Hall meetings
  • The ability to indirectly or directly change the lives of hundreds of thousands patients
  • Multiple medical benefit options
  • employee premiums paid 100% of select plans, dependents covered up to 80%
  • Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
  • Supplemental fertility benefits coverage
  • Retirement savings program including a 4% Company match
  • Increase paid time off with increased tenure
  • Latest and greatest hardware (laptop, lab equipment, facilities)
  • Free daily on-site lunches provided from top eateries
  • A variety of perks on campus (state of the art gym, restaurant)
  • Free on-site EV charging (compatible with all EVs, including Tesla)
  • Generous equity options offering
  • Corporate bonus program

Additional Information:

Job Posted:
December 26, 2025

Employment Type:
Fulltime
Work Type:
On-site work
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