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Seeking an ambitious, curious, and detail-oriented scientist at the Senior Research Associate/Associate Scientist level to join our client's growing team. Working closely with their other R&D scientists, you will help drive drug discovery and development efforts by designing and conducting experiments. This is an exciting opportunity to work with and learn from multidisciplinary teams in a small, fast-paced biotechnology company. The successful candidate should be able to work effectively in a team-oriented environment and be accustomed to delivering robust, high-quality data on a timeline. A key part of this role will be conducting in vivo experiments. In addition to the in-vivo pharmacology role, the successful applicant will have the opportunity to gain experience across all aspects of antibody engineering, including phage and yeast display, immunopeptidomics and mass spectrometry, flow cytometry, and tissue culture.
Job Responsibility:
Animal care and monitoring: Provide daily care and monitoring of mice, including health checks and documentation
Maintain detailed and accurate records of all procedures and animal health status
investigate adverse study events
Tumor implantations: Perform precise implantation or injection of tumor cells into mice to establish models for oncology studies
Monitor and document tumor growth and animal health
Dosing procedures: Administer compounds by all routes (i.v., i.p., s.q., p.o.) accurately and safely
Tissue harvesting: Collect blood, tumor tissue, and organs, including spleen and lymph nodes, for processing and analysis
Compliance and safety: Follow all institutional, local, and federal regulations regarding animal care and use
Adhere to safety protocols and maintain a clean and organized work environment
Meticulous electronic lab notebook documentation
Communicate experimental plans and results to the leadership team
Occasional weekend or holiday work may be necessary depending on study needs
Requirements:
Bachelor's Degree in a relevant discipline (Veterinary Technology, biology, chemistry, animal sciences, or related field) and at least 3-5 years of experience, or a master's degree and at least 2 years of relevant experience
At least 2 years of industry experience in a biotechnology/pharmaceutical company or full-time academic lab experience
Certification as a Veterinary Technician (CVT, LVT, or RVT) preferred
Expertise with oncology studies, including experience with tumor cell implantations and compound dosing, preferred
Knowledge and experience with formulation of small molecules and biologics
Strong verbal and written communication skills to effectively share scientific findings
Passion for working at the bench and in the vivarium to advance programs and solve technical challenges
Self-motivation and adaptability to evolving project priorities and responsibilities
Team-oriented, with a strong work ethic
Ability to learn new techniques for which training will be provided
Nice to have:
Experience culturing cell lines and/or primary immune cells is a plus